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Showing 1–24 of 242 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Suicidal Thoughts and Behaviors Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Trauma-Informed Approach for Positive Youth Development for Montana Students

NCT04664855
View directory record Official record
Conditions
Depression, Anxiety, Suicidal Ideation, Stress, Trauma
Interventions
Trauma-Informed Yoga
Other
Lead sponsor
Montana State University
Other
Eligibility
14 Years to 19 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Nov 14, 2021 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention

NCT04760652
View directory record Official record
Conditions
Depression and Suicide
Interventions
Cognitive Behavioral Therapy CBT, TAU
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Birmingham, Alabama • New Haven, Connecticut • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

Assessment of Emotion Regulation Strategies Used When Suicidal

NCT05722197
View directory record Official record
Conditions
Suicidal Ideation, Treatment Refusal, Emotion Regulation
Interventions
Crisis Response Planning and Lethal Means Safety Counseling
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting Phase 2 Interventional

Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality

NCT06706232
View directory record Official record
Conditions
Bipolar II Disorder, Depression, Bipolar, Suicidality
Interventions
Psilocybin, Therapeutic Support
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
25 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Phase 4 Interventional Results available

Clinical and Imaging Trial of Uridine for Veterans With Suicidal Ideation

NCT03265964
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Uridine, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Sep 17, 2026, 5:15 AM EDT
Terminated Phase 4 Interventional Results available

Fluoxetine and Bupropion to Treat Patients With Depression and Alcoholism

NCT00449007
View directory record Official record
Conditions
Depression, Alcoholism, Suicidal Behavior
Interventions
fluoxetine, bupropion
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Sep 17, 2026, 5:15 AM EDT
Active, not recruiting Not applicable Interventional

Caring for Vets and Service Members: Caring Contacts for Stressed and Distressed Veterans and Service Members

NCT06136234
View directory record Official record
Conditions
Stress, Distress, Emotional
Interventions
Caring Contacts, Best Available Resources Alone
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
521 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Engaging Suicidal Patients in Mental Health Treatment

NCT05021224
View directory record Official record
Conditions
Suicide, Depression, Mental Health Impairment, Suicidal Ideation, Suicidal
Interventions
Caring Contacts, Reminders, Informational Poster, Motivational Interviewing
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 100 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 7, 2025 · Synced Sep 17, 2026, 5:15 AM EDT
Not yet recruiting Not applicable Interventional

Empowerment Self Defense Program for Adult Native Women Survivors of Sexual Violence

NCT07712796
View directory record Official record
Conditions
Depression and Quality of Life, Sexual Violence, PTSD, Suicidal Ideation, Problem Drinking
Interventions
Empowerment self-defense training
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pine Ridge, South Dakota
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Low-Dose Intravenous Ketamine for Adolescents With Depression and Suicidal Ideation in the Emergency Department

NCT05217706
View directory record Official record
Conditions
Depression, Suicidal Ideation
Interventions
Ketamine, normal Saline
Drug
Lead sponsor
Rady Children's Hospital, San Diego
Other
Eligibility
12 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional

Developing and Testing a Brief, Personalized Intervention for Suicidal Thoughts and Behaviors

NCT07749391
View directory record Official record
Conditions
Suicidal Thoughts and Behaviors
Interventions
PRECISE
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 26 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional

Brief Sleep Intervention for Bipolar Disorder

NCT01764074
View directory record Official record
Conditions
Bipolar Disorder, Sleep Problems, Suicidal Thoughts
Interventions
Brief Sleep Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 5, 2019 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention

NCT06809348
View directory record Official record
Conditions
Suicidal Thoughts and Behaviors
Interventions
PRECISE
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Personal Values, Interpersonal Needs, and Suicidal Ideation in a Veteran Population

NCT01118169
View directory record Official record
Conditions
Suicide Prevention
Interventions
Not listed
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 9, 2011 · Synced Sep 17, 2026, 5:15 AM EDT
Suspended Not applicable Interventional

Study to Evaluate the Safety and Efficacy of PEER Interactive Versus Treatment as Usual in Subjects With a Primary Diagnosis of Depression

NCT01794559
View directory record Official record
Conditions
Depressive Disorder
Interventions
PEER Interactive Report
Device
Lead sponsor
MYnd Analytics
Industry
Eligibility
18 Years to 65 Years
Enrollment
1,922 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Safety Planning in Juvenile Justice for Suicidal Youth

NCT03655470
View directory record Official record
Conditions
Suicidal Ideation, Suicide, Attempted, Nonsuicidal Self-injury
Interventions
Safety Planning, Standard care
Behavioral
Lead sponsor
Brown University
Other
Eligibility
12 Years to 18 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS

NCT05977439
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Suicidal Ideation
Interventions
Single-Pulse Transcranial Magnetic Stimulation, EEG-Synchronized Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Behavioral Therapy (CBT), Cognitive Flexibility and Emotion Regulation Tasks
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Zero Suicide Plus KICKS

NCT03924037
View directory record Official record
Conditions
Suicide, Suicidal Ideation, Suicidal Intention, Suicidal and Self-injurious Behavior
Interventions
Intergenerational Knowledge Sharing group, Support group
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
13 Years to 24 Years
Enrollment
222 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

An Adaptive Intervention to Increase Engagement to Community-Based Care After an ED Admission

NCT07092345
View directory record Official record
Conditions
Suicidal and Self-injurious Behavior, Linkage to Care
Interventions
adaptive intervention
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
8 Years to 17 Years
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Terminated Phase 2Phase 3 Interventional

The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal Cognition

NCT03693105
View directory record Official record
Conditions
Major Depressive Disorder, Major Depressive Episode, Suicidal Ideation
Interventions
Active SAINT Stimulation, Sham SAINT Stimulation
Device
Lead sponsor
Magnus Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Iowa City, Iowa • Manhattan, New York • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Sep 17, 2026, 5:15 AM EDT
Enrolling by invitation Not applicable Interventional

Psychotherapy Combined With Intranasal Esketamine for the Treatment of Suicidal Ideation

NCT07396220
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Naturalistic Intranasal Esketamine, Brief Cognitive Behavioral Therapy for Suicide Prevention
Other · Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional

Intensive Outpatient Treatment for Suicidal Veterans

NCT01334372
View directory record Official record
Conditions
Suicidality
Interventions
CAMS
Behavioral
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 89 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 12, 2011 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

TMS for Suicidal Crisis in Active Duty SMs

NCT03014362
View directory record Official record
Conditions
Suicide, Suicidal Ideation, Suicidal Impulses, Suicidal Intention, Suicidal and Self-Injurious Behavior, Suicidal Depression
Interventions
Neuronetics NeuroStar XPLOR magnetic stimulator - Active, Neuronetics NeuroStar XPLOR magnetic stimulator - Sham
Device
Lead sponsor
Eisenhower Army Medical Center
Federal
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced Sep 17, 2026, 5:15 AM EDT
Suspended Phase 4 Interventional

IM Ketamine vs Midazolam for Suicidal ER Patients

NCT04640636
View directory record Official record
Conditions
Depression, Unipolar, Depression, Bipolar, Suicidal Ideation
Interventions
Ketamine hydrochloride injection, Midazolam injection
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 17, 2026, 5:15 AM EDT