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ClinicalTrials.gov public records Last synced Oct 11, 2026, 11:40 PM EDT

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Showing 121–144 of 244 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Suicidal Thoughts and Behaviors Clear all
Suspended Not applicable Interventional

Study to Evaluate the Safety and Efficacy of PEER Interactive Versus Treatment as Usual in Subjects With a Primary Diagnosis of Depression

NCT01794559
View directory record Official record
Conditions
Depressive Disorder
Interventions
PEER Interactive Report
Device
Lead sponsor
MYnd Analytics
Industry
Eligibility
18 Years to 65 Years
Enrollment
1,922 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2020 · Synced Oct 11, 2026, 11:40 PM EDT
Completed Not applicable Interventional

Randomized Controlled Trial of a Single-session Mechanism-focused Intervention for Suicidal Thoughts and Behaviors

NCT05816317
View directory record Official record
Conditions
Suicidal Ideation, Hopelessness, Wish to Live, Wish to Die
Interventions
Single-Session Mechanism-Focused Intervention (SSMFI), Distress Tolerance Skills Review
Behavioral
Lead sponsor
Shannon E. Sauer-Zavala
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 1, 2025 · Synced Oct 11, 2026, 11:40 PM EDT
Completed Phase 3 Interventional

Risperidone and Suicidality in Major Depressive Disorder

NCT00167154
View directory record Official record
Conditions
Depression
Interventions
Risperidone and placebo comparator
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Oct 11, 2026, 11:40 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Primary Care iSBIRT to Reduce Serious Teen Health Risks

NCT00891631
View directory record Official record
Conditions
Substance-related Disorders, Depression, High-risk Sex
Interventions
iSBIRT, iSBIRT/TE
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2016 · Synced Oct 11, 2026, 11:40 PM EDT
Active, not recruiting Not applicable Interventional

The Group Risk Reduction Intervention Therapy (GRRIT) Project

NCT05401838
View directory record Official record
Conditions
Suicidal Ideation, Suicide, Attempted, Coping Skills, Depression, Anxiety, PTSD
Interventions
Group Brief Cognitive-Behavioral Therapy (G-BCBT), Dialectical Behavior Therapy (DBT) Skills Group
Behavioral
Lead sponsor
University of North Carolina, Charlotte
Other
Eligibility
18 Years to 99 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 11, 2026, 11:40 PM EDT
Enrolling by invitation Not applicable Interventional

Intramuscular Ketamine for Suicidal Patients in the Evanston Hospital Emergency Department for Suicidal Distress

NCT07810023
View directory record Official record
Conditions
Suicidal, Suicidal Ideation, Suicidal Ideation and Behavior, Depression / Major Depressive Disorder
Interventions
Ketamine (0.5 mg/kg)
Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 11, 2026, 11:40 PM EDT
Completed Not applicable Interventional

Men and Providers Preventing Suicide (MAPS)

NCT02986113
View directory record Official record
Conditions
Suicidal Intention, Suicidal Ideation, Suicide, Attempted
Interventions
MAPS tailored multimedia patient activation program, Sleep hygiene video, Telephone evidence-based follow-up care, Commitment to Living for Primary Care
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
35 Years to 64 Years · Male only
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Palo Alto, California • Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Oct 11, 2026, 11:40 PM EDT
Recruiting Phase 2Phase 3 Interventional

Ketamine & Crisis Response Plan for Suicidal Ideation in the ED

NCT05696691
View directory record Official record
Conditions
Suicide
Interventions
Ketamine Hydrochloride, Crisis Response Plan
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 11, 2026, 11:40 PM EDT
Recruiting Not applicable Interventional

Integrated Suicide Supports and Safety Planning for Youth

NCT06701006
View directory record Official record
Conditions
Suicidal Ideation, Suicidal Behavior
Interventions
Integrated skills and safety planning app
Other
Lead sponsor
University of Washington
Other
Eligibility
13 Years to 21 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 11, 2026, 11:40 PM EDT
Completed Not applicable Interventional Results available

Drivers of Suicide Mobile App Study

NCT05427734
View directory record Official record
Conditions
Suicide, Suicide, Attempted, Suicidal Ideation, Alcohol Use Disorder, Alcoholism, Alcohol Abuse, Screening and Brief Interventions
Interventions
WisePath for Adults, Active-Control app + electronic wellness resources brochure
Device
Lead sponsor
Evidence-Based Practice Institute, Seattle, WA
Industry
Eligibility
22 Years and older
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 11, 2026, 11:40 PM EDT
Recruiting Not applicable Interventional

Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

NCT05869552
View directory record Official record
Conditions
Suicide, Suicidal Ideation
Interventions
STAT-PC, YST-III
Other
Lead sponsor
Elizabeth Arnold
Other
Eligibility
18 Years to 24 Years
Enrollment
1,485 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Austin, Texas • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 11, 2026, 11:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Conditioning Paradigm to Increase Affinity for Sacredness of Life

NCT05541900
View directory record Official record
Conditions
Suicidal Ideation, Suicide, Attempted, Suicide and Self-harm, Non-suicidal Self-injury
Interventions
TEC-Sacredness, TEC-Control
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Oct 11, 2026, 11:40 PM EDT
Completed Not applicable Interventional Results available

Supplementing Brief Psychotherapy With a Mobile App

NCT05867316
View directory record Official record
Conditions
Suicide and Self-harm, Emotion Regulation
Interventions
Unified Protocol
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 11, 2026, 11:40 PM EDT
Completed Phase 2 Interventional Results available

Sequential Therapy for the Treatment of Severe Bipolar Depression.

NCT02974010
View directory record Official record
Conditions
Bipolar Depression, Suicidal Ideas, Suicidal Ideation, Suicide, Attempted
Interventions
NRX-101 Oral Capsule, Lurasidone Oral Capsule, Ketamine Intravenous Infusion, Saline Solution Intravenous Infusion
Drug
Lead sponsor
NeuroRx, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
4
States / cities
Birmingham, Alabama • Fort Lauderdale, Florida • Charlotte, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Oct 11, 2026, 11:40 PM EDT
Recruiting Not applicable Interventional

Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention

NCT06809348
View directory record Official record
Conditions
Suicidal Thoughts and Behaviors
Interventions
PRECISE
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 11, 2026, 11:40 PM EDT
Recruiting Not applicable Interventional

Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD

NCT06285708
View directory record Official record
Conditions
PTSD, Suicidal Ideation, Suicide, Attempted, Trauma, Psychological
Interventions
Prolonged exposure
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 11, 2026, 11:40 PM EDT
Recruiting Not applicable Interventional

Teen Recovery Through Inspiration, Support, and Empowerment

NCT07170657
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Anxiety, Depression Disorders
Interventions
Peer Support Services Recovery
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
15 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 11, 2026, 11:40 PM EDT
Not listed Phase 3 Interventional

NRX-101 for Maintenance of Remission From Severe Bipolar Depression in Patients With Suicidal Ideation

NCT03396068
View directory record Official record
Conditions
Bipolar Depression, Suicidal Ideation
Interventions
NRX-101, Lurasidone HCl
Drug
Lead sponsor
NeuroRx, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
4
States / cities
Birmingham, Alabama • Hollywood, Florida • Fort Worth, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2024 · Synced Oct 11, 2026, 11:40 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome

NCT02418195
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
ketamine
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
247 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 30, 2022 · Synced Oct 11, 2026, 11:40 PM EDT
Terminated Phase 2 Interventional Results available

Study of Efficacy and Safety of MIJ821 in Addition to Comprehensive Standard of Care on the Rapid Reduction of Symptoms of Major Depressive Disorder in Subjects Who Have Suicidal Ideation With Intent

NCT04722666
View directory record Official record
Conditions
Major Depressive Disorder With Suicidal Ideation With Intent
Interventions
MIJ821 Intravenous Injection, Placebo Intravenous Injection
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
6
States / cities
Birmingham, Alabama • Farmington, Connecticut • Oakland Park, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 11, 2026, 11:40 PM EDT
Recruiting Phase 3 Interventional

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

NCT07227454
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Esketamine, Midazolam, Oral Placebo, Intranasal Placebo
Drug · Other
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
12 Years to 17 Years
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
10
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Atlanta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 11, 2026, 11:40 PM EDT
Recruiting Phase 1 Interventional

Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury

NCT05647044
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Suicidal Ideation, Impulsivity
Interventions
intermittent theta burst stimulation, placebo intermittent theta burst stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
22 Years to 65 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 11, 2026, 11:40 PM EDT
Terminated Phase 4 Interventional Results available

The Effect of Ketamine on the Length of Hospital Stay of Patients Hospitalized With Suicidal Ideation.

NCT02997722
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Ketamine, Normal Saline
Drug
Lead sponsor
Allen Richert
Other
Eligibility
18 Years to 64 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Oct 11, 2026, 11:40 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)

NCT00579267
View directory record Official record
Conditions
Major Depression, Mania, Anxiety Disorders, Psychotic Disorder, Alcohol Dependence, Drug Dependence, Eating Disorders, Suicidality, Dysthymia, ADHD, Tourettes Disorder, Conduct Disorder, Oppositional Defiant Disorder, Pervasive Developmental Disorder
Interventions
MINI-KID
Other
Lead sponsor
University of South Florida
Other
Eligibility
6 Years to 17 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 16, 2009 · Synced Oct 11, 2026, 11:40 PM EDT