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Showing 1–24 of 265 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Suicidal and Self-injurious Behavior Clear all
Completed Not applicable Interventional

Open Pilot Trial Evaluating an Avatar-Guided Intervention for Emerging Adults With Alcohol Use Problems and Suicide Risk

NCT06595862
View directory record Official record
Conditions
Binge Drinking, Suicidal Ideation
Interventions
EA-Avatar
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 29 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Marlborough, Massachusetts • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 25, 2026, 5:05 AM EDT
Completed Not applicable Interventional

An ED-based RCT of Lethal Means Counseling for Parents of At-Risk Youth

NCT03143283
View directory record Official record
Conditions
Suicidal and Self-injurious Behavior
Interventions
Safety Study Lethal Means Counseling
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
10 Years to 17 Years
Enrollment
575 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
8
States / cities
Colorado Springs, Colorado • Fort Collins, Colorado • Loveland, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Sep 25, 2026, 5:05 AM EDT
Recruiting Not applicable Interventional

Assessing Improvements in Mood and Sleep Trial

NCT06639477
View directory record Official record
Conditions
Depression, Suicidality, Sleep
Interventions
Treatment As Usual, Active Condition, Active Comparator
Other · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
55 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
3
States / cities
Los Angeles, California • Augusta, Georgia • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 25, 2026, 5:05 AM EDT
Recruiting Not applicable Interventional

Assessment of Emotion Regulation Strategies Used When Suicidal

NCT05722197
View directory record Official record
Conditions
Suicidal Ideation, Treatment Refusal, Emotion Regulation
Interventions
Crisis Response Planning and Lethal Means Safety Counseling
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 25, 2026, 5:05 AM EDT
Completed Not applicable Interventional

Military Continuity Project

NCT01829620
View directory record Official record
Conditions
Suicidal Ideation Active, Suicidal and Self-injurious Behavior
Interventions
TAU, CCVT+TAU
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
658 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
3
States / cities
Twentynine Palms, California • Fort Bragg, North Carolina • Marine Corps Base Camp Lejeune, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2020 · Synced Sep 25, 2026, 5:05 AM EDT
Completed No phase listed Observational

A Study to Assess the Validation and Mapping of the Suicide Ideation and Behavior Assessment

NCT03085108
View directory record Official record
Conditions
Suicidality
Interventions
No Intervention
Other
Lead sponsor
Janssen Scientific Affairs, LLC
Industry
Eligibility
12 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
4
States / cities
Birmingham, Alabama • Garden Grove, California • Piscataway, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2025 · Synced Sep 25, 2026, 5:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Executive Dysfunction and Suicide in Psychiatric Outpatients and Inpatients

NCT01043432
View directory record Official record
Conditions
Traumatic Brain Injury, Suicidality
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 11, 2015 · Synced Sep 25, 2026, 5:05 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Reducing Self-Dehumanization to Examine Oxytocin and Suicide Risk

NCT06713473
View directory record Official record
Conditions
Rehumanization Intervention, Control Intervention
Interventions
Rehumanized Intervention, Control Intervention, Clinical Interview, Self-Report Measures, Blood Draw
Other · Diagnostic Test
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 25, 2026, 5:05 AM EDT
Recruiting Phase 2 Interventional

Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth

NCT05304065
View directory record Official record
Conditions
Suicide, Suicidal, Self-Harm
Interventions
SAFETY-A within usual ED Care, Combined SAFETY-A within usual ED Care + CLASP Therapeutic Follow-Up Contacts
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
13 Years to 24 Years
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
5
States / cities
Los Angeles, California • Sylmar, California • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Sep 25, 2026, 5:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Classification and Assessment of Mental Health Performance Using Schematics

NCT04275908
View directory record Official record
Conditions
Suicide Ideation, Suicidal Intention, Suicide and Depression
Interventions
MHSAFE app
Device
Lead sponsor
Clarigent Health
Industry
Eligibility
8 Years to 23 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 5, 2024 · Synced Sep 25, 2026, 5:05 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

Lithium for Suicidal Behavior in Mood Disorders

NCT01928446
View directory record Official record
Conditions
Depressive Disorder, Bipolar Disorder, Suicide, Suicide, Attempted
Interventions
Lithium, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
519 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
28
States / cities
Phoenix, Arizona • Tucson, Arizona • North Little Rock, Arkansas + 25 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Sep 25, 2026, 5:05 AM EDT
Terminated Phase 2Phase 3 Interventional

The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal Cognition

NCT03693105
View directory record Official record
Conditions
Major Depressive Disorder, Major Depressive Episode, Suicidal Ideation
Interventions
Active SAINT Stimulation, Sham SAINT Stimulation
Device
Lead sponsor
Magnus Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Iowa City, Iowa • Manhattan, New York • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Sep 25, 2026, 5:05 AM EDT
Recruiting Not applicable Interventional

An Adaptive Intervention to Increase Engagement to Community-Based Care After an ED Admission

NCT07092345
View directory record Official record
Conditions
Suicidal and Self-injurious Behavior, Linkage to Care
Interventions
adaptive intervention
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
8 Years to 17 Years
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 25, 2026, 5:05 AM EDT
Completed Not applicable Interventional

Optimizing Suicide Prevention Strategies for Pediatric Primary Care

NCT06194331
View directory record Official record
Conditions
Suicidal Ideation, Suicidal and Self-injurious Behavior, Depression
Interventions
iCHART/cASAP, Treatment as usual
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Itasca, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 25, 2026, 5:05 AM EDT
Completed Not applicable Interventional

Examining Feasibility, Acceptability, and Sustainability of a Novel Personalized Smartphone Intervention for Suicide - Randomized Trial

NCT05202756
View directory record Official record
Conditions
Suicide and Self-harm, Suicide, Suicide, Attempted, Suicidal Ideation
Interventions
Mobile Application to Prevent Suicide (MAPS), EMA Monitoring Only
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 25, 2026, 5:05 AM EDT
Terminated Phase 2 Interventional

Ketamine for OUD and Suicidal Ideation in the ED

NCT06111339
View directory record Official record
Conditions
Opioid Use Disorder, Suicidal Ideation
Interventions
Ketamine, Saline Solution
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 7, 2025 · Synced Sep 25, 2026, 5:05 AM EDT
Recruiting Not applicable Interventional

Social Threat, Adolescent Relationships, and Suicidality Study

NCT07294079
View directory record Official record
Conditions
Suicidal Thoughts and Behaviors, Social Connectedness, Responses to Social Threat
Interventions
Social threat
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 17 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 25, 2026, 5:05 AM EDT
Completed Phase 4 Interventional Results available

Reducing Suicidal Ideation Through Insomnia Treatment

NCT01689909
View directory record Official record
Conditions
Insomnia, Depression, Suicidal Ideation
Interventions
Zolpidem-CR, Placebo
Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 65 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
4
States / cities
Augusta, Georgia • Durham, North Carolina • Wake Forest, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Sep 25, 2026, 5:05 AM EDT
Enrolling by invitation Not applicable Interventional

Testing the Efficacy of ACT for Life

NCT04829682
View directory record Official record
Conditions
Suicide
Interventions
ACT for Life, Present Centered Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Battle Creek, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 25, 2026, 5:05 AM EDT
Enrolling by invitation Not applicable Interventional

Safety Planning Intervention Telehealth Service Model in Emergency Departments

NCT05307432
View directory record Official record
Conditions
Suicide, Suicidal Ideation
Interventions
SPI+ Delivered by ED Staff, SPI+ Delivered by SPCC Clinicians
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
2,814 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 25, 2026, 5:05 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

MicroRNA Correlates of Childhood Maltreatment and Suicidality

NCT04923685
View directory record Official record
Conditions
Major Depressive Disorder, Suicidal Ideation
Interventions
Trier Social Stress Test
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 60 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Birmingham, Alabama • Huntsville, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 25, 2026, 5:05 AM EDT
Completed Phase 1 Interventional

Mindfulness-Based Cognitive Therapy + Safety Planning For Suicidal Behavior

NCT01826240
View directory record Official record
Conditions
Monopolar Depression, Single Episode or Unspecified, Suicidal and Self-injurious Behaviour
Interventions
MBCT+SPI
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 3, 2015 · Synced Sep 25, 2026, 5:05 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents

NCT05437588
View directory record Official record
Conditions
Major Depressive Disorder, Suicidal Ideas, Suicide, Attempted, MDD, Depression, Depression, Teen, Depression and Suicide, Depression in Adolescence, Suicide
Interventions
Genetic testing
Genetic
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
10 Years to 24 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
2
States / cities
Birmingham, Alabama • Huntsville, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 25, 2026, 5:05 AM EDT
Completed Not applicable Interventional Results available

Examining Feasibility, Acceptability, and Sustainability of a Novel Personalized Smartphone Intervention for Suicide - Open Trial

NCT05180383
View directory record Official record
Conditions
Suicide and Self-harm, Suicide, Suicide, Attempted, Suicidal Ideation
Interventions
Mobile Application to Prevent Suicide (MAPS)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 25, 2026, 5:05 AM EDT