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Showing 1–24 of 370 matching trials from the live ClinicalTrials.gov search.
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Conditions
Suicide Attempt, Suicide Ideation
Interventions
Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Suicide
Interventions
Socio-Cognitive Behavioral Therapy for Suicidal Behavior (SCBT-SB), Treatment as Usual
Behavioral
Lead sponsor
Bradley Hospital
Other
Eligibility
12 Years to 17 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Providence, Rhode Island • Riverside, Rhode Island
Conditions
Nightmare
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
6 Years to 17 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Tulsa, Oklahoma
Conditions
PTSD, Suicidal Thoughts and Behaviors, PTSD Symptoms, Depressive Symptoms
Interventions
1-(2-[+F]fluoroethyl)-L-tryptophan
Drug
Lead sponsor
Wayne State University
Other
Eligibility
19 Years to 69 Years
Enrollment
100 participants
Timeline
2025 – 2030
U.S. locations
1
States / cities
Detroit, Michigan
Completed Phase 2 Interventional Results available

Ketamine for Depression and Suicide Risk

NCT02094898
Conditions
Depression, Suicide
Interventions
Ketamine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional

Culture and Well-Being for Latinos

NCT05244733
Conditions
Social Isolation, Loneliness, Suicidal Ideation
Interventions
Social Engage (S-ENGAGE), The Healthy Lifestyles Education Program
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Rochester, New York
Conditions
Binge Alcohol Consumption, Suicidal Ideation
Interventions
EA-Avatar, Suicide safety planning app
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 29 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Marlborough, Massachusetts • Worcester, Massachusetts
Conditions
Suicide, Suicide and Self-harm, Suicide, Attempted, Suicidal Ideation
Interventions
Mobile Application to Prevent Suicide (MAPS)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 26 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Suicidal Ideation, Treatment-resistant Depression
Interventions
Accelerated Theta Burst Stimulation
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
San Diego, California
Conditions
Suicidal Ideation, Suicide Attempt
Interventions
Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S), Smartphone-delivered inactive Therapeutic Evaluative Conditioning
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Opioid-use Disorder, Addiction, Depression, Post Traumatic Stress Disorder, Suicidal Ideation
Interventions
Collaborative care Plus
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Los Angeles, California • Santa Monica, California • Albuquerque, New Mexico + 3 more
Conditions
Suicide
Interventions
Phone call, Text messaging, Automated interactive smartphone-based tool, Non-interactive pop-up messages
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

Group Depression Treatment for Autistic Youth

NCT05430022
Conditions
Autism Spectrum Disorder, Depression, Suicidal Ideation, Self Esteem
Interventions
Autism-adapted Group Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
11 Years to 17 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Major Depressive Disorder
Interventions
Esketamine, Placebo
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 64 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
14
States / cities
Birmingham, Alabama • San Diego, California • Hartford, Connecticut + 11 more
Conditions
Suicide
Interventions
STAT-ED Intervention
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 17 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
2
States / cities
Cincinnati, Ohio • Columbus, Ohio
Conditions
Suicidal Ideation, Self Harm
Interventions
AMPERE EMA app
Other
Lead sponsor
University of Washington
Other
Eligibility
16 Years to 30 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Suicide
Interventions
Personalized internal and external coping strategies, Personalized internal coping strategies, Personalized external coping strategies, General internal and external coping strategies, General internal coping strategies, General external coping strategies, General internal coping strategies, relaxation, General internal coping strategies, distraction, General internal coping strategies, physical activity
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Belmont, Massachusetts • Boston, Massachusetts
Conditions
Suicidal Ideation
Interventions
Estradiol Transdermal Patch 0.1 mg/24 hrs, Oral Micronized Progesterone, Inactive Clear Patch, Placebo capsule
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Suicidal Ideation
Interventions
Uridine, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Suicidal Ideation
Interventions
Behavior Activation, Usual Community Care
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
50 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Suicidal Behavior, Self-Harm, Deliberate, Suicidal Ideation, Suicide
Interventions
Stepped Care for Suicide Prevention, Zero Suicide Quality Improvement
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 24 Years
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Los Angeles, California • Portland, Oregon
Enrolling by invitation No phase listed Observational

Youth Depression and Suicide Research Network

NCT04572321
Conditions
Depression, Suicide, Suicidal Ideation, Suicide, Attempted, Depressive Disorder, Depressive Symptoms, Depressive Episode, Depression and Suicide, Depression, Teen, Depression, Anxiety
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
8 Years to 20 Years
Enrollment
5,000 participants
Timeline
2020 – 2032
U.S. locations
1
States / cities
Dallas, Texas
Completed Phase 4 Interventional Results available

Reducing Suicidal Ideation Through Insomnia Treatment

NCT01689909
Conditions
Insomnia, Depression, Suicidal Ideation
Interventions
Zolpidem-CR, Placebo
Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 65 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
4
States / cities
Augusta, Georgia • Durham, North Carolina • Wake Forest, North Carolina + 1 more
Conditions
Suicide Ideation, Suicidal Behaviors, Depressive Symptoms
Interventions
Socio-Cognitive Behavioral Therapy for Suicidal Behavior (SCBT-SB), SCBT-SB + CHW
Behavioral
Lead sponsor
Bradley Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island