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Showing 1–24 of 149 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Suicide Attempt Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents

NCT05437588
View directory record Official record
Conditions
Major Depressive Disorder, Suicidal Ideas, Suicide, Attempted, MDD, Depression, Depression, Teen, Depression and Suicide, Depression in Adolescence, Suicide
Interventions
Genetic testing
Genetic
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
10 Years to 24 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
2
States / cities
Birmingham, Alabama • Huntsville, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 22, 2026, 10:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biomarkers as Predictors of Suicidal Risk in Adolescents

NCT03014518
View directory record Official record
Conditions
Suicide, Attempted, Suicidal Ideation, Suicidal Intention, Suicide
Interventions
Clinical assessments and blood samples; follow-up for 12 mos, Clinical assessments and blood samples; no 12mo follow-up
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
12 Years to 18 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 15, 2021 · Synced Jul 22, 2026, 10:43 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Teen Brain Training (TBT)

NCT06183580
View directory record Official record
Conditions
Suicide, Attempted, Suicide, Ideation, Depression
Interventions
neurofeedback training involving dACC, neurofeedback training involving amygdala
Other
Lead sponsor
University of Minnesota
Other
Eligibility
11 Years to 18 Years
Enrollment
157 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Jul 22, 2026, 10:43 AM EDT
Not listed Not applicable Interventional

Strategic Disclosure Intervention for Suicide Attempt Survivors

NCT05018897
View directory record Official record
Conditions
Suicide, Attempted, Mood Disorders
Interventions
To Share or Not to Share, Peer Support
Behavioral
Lead sponsor
Illinois Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced Jul 22, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional

Efficacy of the I-CARE Digital Health Intervention

NCT07150832
View directory record Official record
Conditions
Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
Interventions
Improving Care, Accelerating Recovery & Education (ICARE)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 17 Years
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
New Haven, Connecticut • Hanover, New Hampshire • Lebanon, New Hampshire + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Jul 22, 2026, 10:43 AM EDT
Completed Not applicable Interventional Results available

Mobile Technology for Reducing and Preventing Adolescent Suicide

NCT04896593
View directory record Official record
Conditions
Suicide, Attempted, Suicidal Ideation
Interventions
Smartphone App
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 29, 2023 · Synced Jul 22, 2026, 10:43 AM EDT
Not yet recruiting Not applicable Interventional

Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial

NCT07628192
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Safety Plan, Depression / Major Depressive Disorder, Hopelessness
Interventions
CAMS Brief Intervention, Stanley-Brown Safety Planning Intervention
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
12 Years to 17 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 22, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional

Stepped Approach to Reducing Risk of Suicide in Primary Care

NCT06018285
View directory record Official record
Conditions
Suicidal Ideation, Suicide, Attempted, Suicide Prevention
Interventions
Stepped Approach to Reducing Risk of Suicide in Primary Care
Behavioral
Lead sponsor
Cynthia Fontanella
Other
Eligibility
12 Years to 17 Years
Enrollment
2,572 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
15
States / cities
Akron, Ohio • Ashtabula, Ohio • Athens, Ohio + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Jul 22, 2026, 10:43 AM EDT
Completed Not applicable Interventional

Feasibility Study of a Software Application for Patients Hospitalized After Suicidal Ideation or Suicide Attempts

NCT04295382
View directory record Official record
Conditions
Suicide, Attempted, Suicidal Ideation
Interventions
Software Application
Device
Lead sponsor
Oui Therapeutics, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Jul 22, 2026, 10:43 AM EDT
Completed Phase 4 Interventional Results available

Paroxetine/Bupropion in Depression With Suicide Attempt or Thoughts: fMRI Study

NCT01748955
View directory record Official record
Conditions
Depression, Suicidal Ideation
Interventions
Paroxetine CR for Major Depressive Episode, Bupropion XL for Major Depressive Episode
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2017 · Synced Jul 22, 2026, 10:43 AM EDT
Completed Not applicable Interventional

Suicide Prevention Among Recipients of Care

NCT04893447
View directory record Official record
Conditions
Suicide, Suicide, Attempted, Suicidal Ideation, Social Support, Secondary Prevention, Patient Care Planning, Outpatients, Outpatient Clinics, Hospital, Mental Health Services, Mental Health, Mental Disorder, Loneliness, Emergency Service, Hospital, Depressive Disorder, Depression, Continuity of Patient Care, Ambulatory Care, Adolescent, Adult, Crisis Intervention
Interventions
SPI+, SP+CC (Caring Contacts)
Behavioral
Lead sponsor
St. Luke's Health System, Boise, Idaho
Other
Eligibility
12 Years and older
Enrollment
1,520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Jul 22, 2026, 10:43 AM EDT
Completed Not applicable Interventional

Real-time Intervention for Suicide Risk Reduction

NCT05848089
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt
Interventions
Brief skills sessions plus EMI skills practice prompts, Ecological momentary assessment (EMA), Treatment as usual (TAU)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jul 22, 2026, 10:43 AM EDT
Completed Not applicable Interventional

Safety Planning Intervention to Reduce Short Term Risk

NCT03227991
View directory record Official record
Conditions
Suicide, Attempted
Interventions
Safety Planning Intervention, Risk factors and Warning signs
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years and older
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Worcester, Massachusetts • New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Jul 22, 2026, 10:43 AM EDT
Completed Not applicable Interventional

Electronic Bridge to Mental Health for College Students

NCT03380117
View directory record Official record
Conditions
Suicide, Depression
Interventions
eBridge Online Counseling
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
6,241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
4
States / cities
Stanford, California • Iowa City, Iowa • Ann Arbor, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Jul 22, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional

Text-based Support for Parents of Adolescents Following an Emergency Department Visits

NCT06660199
View directory record Official record
Conditions
Suicide
Interventions
Text-based intervention
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Ann Arbor, Michigan • Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jul 22, 2026, 10:43 AM EDT
Completed Not applicable Interventional

Caring Letters for Military Suicide Prevention

NCT01473771
View directory record Official record
Conditions
Suicide, Suicide, Attempted
Interventions
Caring Letter (email)
Behavioral
Lead sponsor
National Center for Telehealth and Technology
Federal
Eligibility
18 Years and older
Enrollment
1,319 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
5
States / cities
Palo Alto, California • San Diego, California • Honolulu, Hawaii + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 22, 2018 · Synced Jul 22, 2026, 10:43 AM EDT
Active, not recruiting Not applicable Interventional

Caring Contacts: A Strength-based, Suicide Prevention Trial in 4 Native Communities

NCT02825771
View directory record Official record
Conditions
Suicidal Ideation, Suicide, Attempted
Interventions
Caring Contacts Messages, Usual Care
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
711 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Jul 22, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional

Randomized Clinical Trial of Supplementing Brief Psychotherapy With a Mobile App

NCT06555094
View directory record Official record
Conditions
Suicidal Ideation, Suicide, Suicide Attempt
Interventions
Ecological momentary assessment (EMA), Treatment as usual (TAU), Brief skills sessions plus EMI skills practice prompts
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 14, 2024 · Synced Jul 22, 2026, 10:43 AM EDT
Not listed No phase listed Observational

CAMPUS Expanded "Classification and Assessment of Mental Health Performance Using Semantics Expanded"

NCT04493736
View directory record Official record
Conditions
Suicide, Suicidal, Suicide, Attempted, Suicidal Ideation, Depression, Anxiety, Aggression, Trauma, Psychological
Interventions
MHSAFE app recording
Behavioral
Lead sponsor
Clarigent Health
Industry
Eligibility
8 Years to 75 Years
Enrollment
2,000 participants
Timeline
2020 – 2024
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 5, 2024 · Synced Jul 22, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional

Nudging Parental Actions for Youth Suicide Prevention

NCT07383714
View directory record Official record
Conditions
Suicide, Suicide Attempt
Interventions
Text-messaging for safety reminders, Text-messaging with safety reminders and risk framing
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
13 Years to 17 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jul 22, 2026, 10:43 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Neural Correlates of Suicidal Behavior in Youth

NCT07568054
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Suicidal Behavior, Depression / Major Depressive Disorder, Hopelessness, Neurobiological
Interventions
CAMS
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
14 Years to 24 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 22, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional

Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A

NCT06223867
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Self Harm
Interventions
Jaspr App + JAH, ETAU
Device · Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
670 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Jul 22, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional

Improving Coping to Reduce Suicide Risk Following ED Discharge

NCT06614946
View directory record Official record
Conditions
Suicidal, Suicide, Attempted, Suicidal Ideation
Interventions
Electronic Safety Plan (ESP), Text support
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Jul 22, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Firearm Storage in Alaska Native Villages

NCT00643812
View directory record Official record
Conditions
Suicide, Suicide, Attempted, Wounds and Injuries
Interventions
Installation of gun locker in household
Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years and older
Enrollment
266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 25, 2008 · Synced Jul 22, 2026, 10:43 AM EDT