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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:39 AM EDT

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Showing 49–65 of 65 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sun-Damaged Skin Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

Effect of Revival Soy on Weight Loss and Skin, Hair, and Nails in Premenopausal Women

NCT00352157
View directory record Official record
Conditions
Skin Aging, Weight Loss
Interventions
Revival Soy Dietary Supplement
Behavioral
Lead sponsor
Physicians Pharmaceuticals, Inc.
Industry
Eligibility
25 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2009 · Synced Oct 21, 2026, 5:39 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

VELOS for the Treatment of Vascular Lesions and Skin Rejuvenation

NCT02468453
View directory record Official record
Conditions
Vascular Lesions, Photoaging
Interventions
velos
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
4
States / cities
San Diego, California • Wayland, Massachusetts • Edina, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Oct 21, 2026, 5:39 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles

NCT06571721
View directory record Official record
Conditions
Collagen Degeneration, Wrinkle, Pigmentation, Elastic Skin, Sebum Deficiency
Interventions
Topical Product: Almond Oil, Topical Product: Almond oil augmented with 0.5% Vitamin E, Topical Product: 0.025% Tretinoin oil augmented with castor oil
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced Oct 21, 2026, 5:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

AI-Personalized Skincare Regimen for Facial Photoaging in Women

NCT07879833
View directory record Official record
Conditions
Photoaging, Skin Aging
Interventions
AI-personalized skin longevity regimen
Other
Lead sponsor
MDalgorithms Inc.
Industry
Eligibility
35 Years to 65 Years · Female only
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 21, 2026, 5:39 AM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Efficacy Evaluation of Products Against Long Wavelength Ultraviolet A1 and Visible Light Induced Biological Effects

NCT04181476
View directory record Official record
Conditions
Sun Damaged Skin
Interventions
Sunscreening Agents
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 28, 2022 · Synced Oct 21, 2026, 5:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies

NCT06351358
View directory record Official record
Conditions
Photoaging, Weight Loss, Skin Laxity, Photodamaged Skin, Volume Deficiency of the Midface
Interventions
Sculptra treatment, Restylane Treatment
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Washington D.C., District of Columbia • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 21, 2026, 5:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Singlet Oxygen Quantification After Skin Exposure to Ultraviolet A (UVA) Light

NCT05865431
View directory record Official record
Conditions
Sun Damaged Skin
Interventions
Zinc Oxide and Avobenzone
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 21, 2026, 5:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Evaluate the Long-Term Efficacy and Tolerability of a Daily Anti-Aging Daily Serum

NCT05514782
View directory record Official record
Conditions
Photoaging, Wrinkle
Interventions
Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 40+
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
30 Years to 60 Years · Female only
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
West Chester, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 27, 2022 · Synced Oct 21, 2026, 5:39 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

TCA 15% Chemical Peel for Improvement in Hand Lentigines

NCT05471947
View directory record Official record
Conditions
Photoaging, Lentigo
Interventions
15% Trichloroacetic acid + 3% glycolic acid
Drug
Lead sponsor
Main Line Center for Laser Surgery
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Oct 21, 2026, 5:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Hybrid-Fractional Laser for Facial Rejuvenation

NCT06436261
View directory record Official record
Conditions
Photoaging, Wrinkle, Skin Laxity
Interventions
Hybrid Fractional Laser, Facial Cleanser, Facial Moisturizer, Sunscreen
Procedure · Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Atlanta, Georgia • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2024 · Synced Oct 21, 2026, 5:39 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Xeomin, Radiesse, and Belotero Facial/Neck Rejuvenational

NCT05039723
View directory record Official record
Conditions
Photoaging
Interventions
Radiesse, Xeomin, Belotero
Drug
Lead sponsor
Main Line Center for Laser Surgery
Other
Eligibility
22 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Oct 21, 2026, 5:39 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Efficacy of Polypodium Leucotomos Extract Decreasing UVA Premutagenic and Photoaging Markers

NCT00520910
View directory record Official record
Conditions
Aging, Skin Abnormalities
Interventions
Polypodium leucotomos
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 18, 2019 · Synced Oct 21, 2026, 5:39 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Clinical Evaluation of Day and Night Skin Care Creams Supplemented With MediCell Technology (MCT)'s Composition of Defensins and Supportive Molecules

NCT02765763
View directory record Official record
Conditions
Skin Aging, Photoaging of Skin
Interventions
2-Minute Reveal Masque, 24/7 Barrier Repair Cream, 8-in-1 BioSerum, Null Formula 2-Minute Reveal Masque, Null Formula 24/7 Barrier Repair Cream, Null Formula 8-in-1 BioSerum
Drug
Lead sponsor
Advanced Dermatology
Other
Eligibility
40 Years to 75 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lincolnshire, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 11, 2018 · Synced Oct 21, 2026, 5:39 AM EDT
Terminated Phase 2 Interventional Results available

Treatment With Dasatinib in Patients With Acral Lentiginous, Mucosal, or Chronic Sun-damaged Melanoma

NCT01092728
View directory record Official record
Conditions
Melanoma
Interventions
Dasatinib, Surgical Resection
Drug · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 5, 2016 · Synced Oct 21, 2026, 5:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of an LED Face Mask & Neck and Chest Mask On Skin Health

NCT07025837
View directory record Official record
Conditions
Skin Aging, Sun Damaged Skin
Interventions
iRESTORE Illumina LED Face Mask and Neck & Chest Mask
Device
Lead sponsor
Freedom Laser, Inc.
Industry
Eligibility
25 Years to 55 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 21, 2026, 5:39 AM EDT
Completed Phase 2 Interventional Results available

Nilotinib in TKI Resistant or Intolerant Patients With Metastatic Mucosal, Acral, or Chronically Sun Damaged Melanoma

NCT00788775
View directory record Official record
Conditions
Mucosal Lentiginous Melanoma, Acral Melanoma, Melanoma
Interventions
Nilotinib
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
8
States / cities
Santa Monica, California • Aurora, Colorado • Tampa, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 15, 2018 · Synced Oct 21, 2026, 5:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging

NCT04586816
View directory record Official record
Conditions
Photoaging, Hyperpigmentation, Rhytides
Interventions
1% red maple leaf extract in cream base, 5% red maple leaf extract, vehicle
Combination Product
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
30 Years to 70 Years · Female only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 14, 2020 · Synced Oct 21, 2026, 5:39 AM EDT