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ClinicalTrials.gov public records Last synced Oct 22, 2026, 10:23 PM EDT

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Showing 1–24 of 39 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Surgery With General Anesthesia Clear all
Recruiting Not applicable Interventional

Limiting Emergence Phenomena After General Anesthesia With Combined LMA and ETT Airway Management Technique

NCT02708836
View directory record Official record
Conditions
Limit Emergence Phenomena After General Anesthesia
Interventions
Induction of anesthesia, Placement of LMA [Ambu (R) AuraGain (TM) disposable laryngeal mask], Laryngoscopy and placement of ETT, Ventilation via the ETT, Removal of the ETT, Intubation of the trachea through the LMA, Ventilation via the LMA, Emergence from anesthesia
Procedure · Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effect of Povidone-iodine Ophthalmic Surgical Prep Solution on Respiration in Children Undergoing Strabismus Surgery With General Anesthesia.

NCT03349515
View directory record Official record
Conditions
Strabismus
Interventions
Provodine-Iodine Solution, Group B will receive three drops in each eye of ophthalmic balanced salt solution.
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
1 Year to 17 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 16, 2019 · Synced Oct 22, 2026, 10:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study to Determine Incidence of Hypoventilation in Patients Who Have Undergone Gastric Bypass

NCT00316446
View directory record Official record
Conditions
Morbid Obesity, Bariatric Surgery
Interventions
Not listed
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 20, 2012 · Synced Oct 22, 2026, 10:23 PM EDT
Recruiting Phase 4 Interventional

The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

NCT06802224
View directory record Official record
Conditions
Anesthesia, Surgery With General Anesthesia, Noncardiac Surgery, Hypotension During Surgery, Acute Kidney Injury (AKI), Myocardial Injury After Noncardiac Surgery (MINS), Vasopressor
Interventions
Norepinephrine, Phenylephrine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
18,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
9
States / cities
San Francisco, California • College Park, Maryland • Ann Arbor, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 22, 2026, 10:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Investigation of an Eye-Tracking Device as a Predictor of Delirium in the Recovery Room After Surgery With General Anesthesia

NCT05579093
View directory record Official record
Conditions
Delirium
Interventions
Cognitive test + Pupillary measure
Combination Product
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
325 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Phase 4 Interventional Results available

Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery.

NCT02996591
View directory record Official record
Conditions
Nerve Block, General Anesthesia, Spinal Anesthesia, Pain, Postoperative Nausea and Vomiting
Interventions
25 mL of 0.25% bupivacaine plus 2 mg preservative-free (PF) dexamethasone / 30 ml for popliteal nerve block, 10 mL of 0.25% bupivacaine plus 2 mg preservative-free (PF) dexamethasone / 30 ml for adductor canal nerve block, Midazolam, 2-5 mg IV + Glycopyrrolate, 0.1 mg IV + Ketamine, 10-20 mg + propofol as needed, 45-60 mg of 1.5% mepivacaine for spinal anesthesia, LMA insertion + titrated propofol infusion + sevoflurane + ketamine 10 mg/hr for general anesthesia
Procedure · Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 75 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Phase 4 Interventional Results available

Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery

NCT02635542
View directory record Official record
Conditions
Neuromuscular Blockade, Postoperative Complications
Interventions
Succinylcholine, Cisatracurium
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Oct 22, 2026, 10:23 PM EDT
Terminated Phase 2 Interventional

A Study of Danavorexton in People With Obstructive Sleep Apnea After General Anesthesia for Abdominal Surgery

NCT05814016
View directory record Official record
Conditions
Sleep Apnea
Interventions
Danavorexton, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
30 Years to 75 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
19
States / cities
Sheffield, Alabama • Phoenix, Arizona • La Jolla, California + 14 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Phase 4 Interventional Results available

Effect IV Ibuprofen and Inflammatory Responses

NCT01938040
View directory record Official record
Conditions
Gallbladder Disease
Interventions
ibuprofen, sugar water/placebo
Drug · Other
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
4
States / cities
Newark, New Jersey • Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 21, 2016 · Synced Oct 22, 2026, 10:23 PM EDT
Recruiting Not applicable Interventional

Non-inferiority Trial Between Sotair® Device Attached to Manual Resuscitator Versus Mechanical Ventilation

NCT06117683
View directory record Official record
Conditions
Airway Management, Respiration, Artificial
Interventions
ADULT Sotair Device
Device
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 22, 2026, 10:23 PM EDT
Recruiting Phase 4 Interventional

Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia

NCT06757075
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Ibuprofen, Acetominophen
Drug
Lead sponsor
Boston University
Other
Eligibility
4 Years to 6 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Brighton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 22, 2026, 10:23 PM EDT
Terminated Phase 4 Interventional Results available

Effect of Intravenous Ibuprofen on Inflammatory Responses in Patients Undergoing Surgery With General Anesthesia.

NCT01377441
View directory record Official record
Conditions
Inflammatory Response
Interventions
Ibuprofen, Placebo/Saline solution
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2017 · Synced Oct 22, 2026, 10:23 PM EDT
Completed No phase listed Observational

Prognostic Factors Associated With Postoperative Cognitive Dysfunction After Surgery

NCT03443440
View directory record Official record
Conditions
Postoperative Cognitive Dysfunction
Interventions
Neurocognitive Testing
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
50 Years to 99 Years
Enrollment
57 participants
Timeline
2018 – 2020
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 22, 2026, 10:23 PM EDT
Terminated No phase listed Observational

Patients With Positive Urine Cocaine Metabolites Undergoing General Anesthesia

NCT01788202
View directory record Official record
Conditions
Emergent Surgery
Interventions
Not listed
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 60 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced Oct 22, 2026, 10:23 PM EDT
Completed No phase listed Observational

Evaluation of a Respiratory Monitor in Surgical Patients With a BMI>35

NCT01825278
View directory record Official record
Conditions
Obesity, Obstructive Sleep Apnea
Interventions
ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.

NCT02025075
View directory record Official record
Conditions
Intraoperative Complications, Postoperative Complications, Laparoscopy, Surgical Complications From General Anesthesia, Ventilator-Induced Lung Injury
Interventions
Rocuronium
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 22, 2026, 10:23 PM EDT
Completed No phase listed Observational Results available

Post- Surgery Recovery: Nerve Blocks w/ Sedation vs. Nerve Block w/ Either Sedation/Gen. Anesthesia

NCT02602080
View directory record Official record
Conditions
Nausea, Emesis
Interventions
Not listed
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 99 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2019 · Synced Oct 22, 2026, 10:23 PM EDT
Completed No phase listed Observational

POCD in Elderly Patients Following Desflurane or Sevoflurane General Anesthesia

NCT01199913
View directory record Official record
Conditions
1. Postoperative Cognitive Dysfunction
Interventions
The intervention will be Mini-Mental Status Examination (MMSE)
Other
Lead sponsor
Loma Linda University
Other
Eligibility
65 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Sep 9, 2014 · Synced Oct 22, 2026, 10:23 PM EDT
Terminated Phase 4 Interventional Results available

Multi-dose Acetaminophen for Patients Undergoing General Anesthesia

NCT02832687
View directory record Official record
Conditions
Recovery Following Cholecystectomy
Interventions
Acetaminophen, normal saline
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Newark, New Jersey • Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Comparing Desflurane to Sevoflurane for the Effect on Recovery Time in Patients Undergoing Urological Cystoscope Surgery

NCT01219881
View directory record Official record
Conditions
Cystoscopes, Baxter Anaesthesia Brand of Desflurane, Sevoflurane
Interventions
Desflurane, Sevoflurane
Drug
Lead sponsor
Ohio State University
Other
Eligibility
50 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 16, 2021 · Synced Oct 22, 2026, 10:23 PM EDT
Enrolling by invitation Phase 3 Interventional Accepts healthy volunteers

GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries

NCT05444751
View directory record Official record
Conditions
Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
Interventions
General anesthetic, SA + ESP
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Efficacy and Safety of HSK3486 Compared to Propofol for Adults Undergoing Elective Surgery With General Anesthesia

NCT05478174
View directory record Official record
Conditions
General Anesthesia
Interventions
HSK3486, Propofol
Drug
Lead sponsor
Haisco-USA Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 99 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
23
States / cities
Sheffield, Alabama • Phoenix, Arizona • Davis, California + 19 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2025 · Synced Oct 22, 2026, 10:23 PM EDT
Completed Not applicable Interventional Results available

A Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia

NCT02190903
View directory record Official record
Conditions
Postoperative Complications, Hip Fracture, Delirium
Interventions
General endotracheal anesthesia, Regional (spinal) Anesthesia
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 30, 2018 · Synced Oct 22, 2026, 10:23 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Does Spinal Anesthesia for Prolapse Surgery With Lead to Urinary Retention?

NCT02547155
View directory record Official record
Conditions
Urinary Retention, Uterine Prolapse
Interventions
Spinal anesthesia, General anesthesia
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 22, 2026, 10:23 PM EDT