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ClinicalTrials.gov public records Last synced Oct 9, 2026, 5:53 AM EDT

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Showing 25–48 of 50 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Surgery for Congenital Heart Disease Clear all
Recruiting Not applicable Interventional

Autus Valve Continued Access Study (CAS)

NCT07466745
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Pulmonary Valve Replacement Surgery
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
18 Months to 16 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2036
U.S. locations
10
States / cities
Los Angeles, California • Aurora, Colorado • Atlanta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 9, 2026, 5:53 AM EDT
Withdrawn Not applicable Interventional

Iron Prophylaxis for Anemia in Infants With Cyanotic Congenital Heart Disease

NCT00459225
View directory record Official record
Conditions
Anemia
Interventions
Iron (ferrous sulfate)
Drug
Lead sponsor
Emory University
Other
Eligibility
Up to 2 Months
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 9, 2014 · Synced Oct 9, 2026, 5:53 AM EDT
Terminated Phase 1 Interventional

Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery: Proposal for Pilot Investigation

NCT02519335
View directory record Official record
Conditions
Heart Defects, Congenital
Interventions
Dexrazoxane
Drug
Lead sponsor
Medical City Children's Hospital
Other
Eligibility
1 Day to 6 Months
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 26, 2018 · Synced Oct 9, 2026, 5:53 AM EDT
Completed No phase listed Observational

BabySparks Developmental Application Pilot Study

NCT03867903
View directory record Official record
Conditions
Development, Child, Adherence, Patient, Congenital Heart Disease
Interventions
Babysparks Application, pre and post-test Redcap Survey
Device · Other
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
Up to 18 Months
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Oct 9, 2026, 5:53 AM EDT
Completed Phase 1 Interventional

Safety Study of Autologous Umbilical Cord Blood Cells for Treatment of Hypoplastic Left Heart Syndrome

NCT01883076
View directory record Official record
Conditions
Hypoplastic Left Heart Syndrome
Interventions
autologous cell-based delivery
Biological
Lead sponsor
Timothy J Nelson, MD, PhD
Other
Eligibility
Up to 18 Months
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
6
States / cities
Los Angeles, California • Aurora, Colorado • Minneapolis, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2022 · Synced Oct 9, 2026, 5:53 AM EDT
Completed Phase 1Phase 2 Interventional

Citrulline for Children Undergoing Cardiopulmonary Bypass Surgery

NCT00201214
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Heart Defects, Congenital
Interventions
Citrulline
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
Up to 18 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 12, 2013 · Synced Oct 9, 2026, 5:53 AM EDT
Not listed Not applicable Interventional

Nasal vs. Oral Intubation for Neonates Requiring Cardiac Surgery

NCT05378685
View directory record Official record
Conditions
Congenital Heart Disease, Oral Aversion
Interventions
Endotracheal intubation
Procedure
Lead sponsor
University of Virginia
Other
Eligibility
Up to 2 Weeks
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Oct 9, 2026, 5:53 AM EDT
Completed Phase 1 Interventional

Study of Autologous Bone Marrow Derived Mononuclear Cells for Treatment of Ebstein Anomaly

NCT02914171
View directory record Official record
Conditions
Ebstein Anomaly
Interventions
Autologous Bone Marrow-derived Mononuclear Cells, Insertable cardiac monitor
Biological · Device
Lead sponsor
Timothy J. Nelson
Other
Eligibility
6 Months to 30 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Oct 9, 2026, 5:53 AM EDT
Terminated No phase listed Observational

Infection in DiGeorge Following CHD Surgery

NCT00278005
View directory record Official record
Conditions
DiGeorge Syndrome, Congenital Heart Defects
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 15 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2008
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 16, 2012 · Synced Oct 9, 2026, 5:53 AM EDT
Completed No phase listed Observational

Pro-Calcitonin Levels Following Pediatric Cardiac Surgery

NCT00284570
View directory record Official record
Conditions
Congenital Heart Disease, Sepsis, Infection
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
Up to 5 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 27, 2013 · Synced Oct 9, 2026, 5:53 AM EDT
Completed Not applicable Interventional

The Use of Music for Neonates Post-Cardiac Surgery

NCT03925584
View directory record Official record
Conditions
Heart Defects, Congenital
Interventions
Music Therapy
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Days to 30 Days
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Oct 9, 2026, 5:53 AM EDT
Completed No phase listed Observational

Biomarker Study for Heart Failure in Children With Single Ventricle Physiology

NCT00571233
View directory record Official record
Conditions
Tricuspid Atresia, Hypoplastic Left Heart Syndrome, Unbalanced AV Canal
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
1 Month to 6 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 14, 2015 · Synced Oct 9, 2026, 5:53 AM EDT
Active, not recruiting Phase 1 Interventional

Mesenchymal Stromal Cells for Infants With Congenital Heart Disease (MedCaP)

NCT04236479
View directory record Official record
Conditions
Congenital Heart Disease (CHD)
Interventions
BM-MSC
Biological
Lead sponsor
Catherine Bollard
Other
Eligibility
Up to 6 Months
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 9, 2026, 5:53 AM EDT
Terminated Phase 3 Interventional Results available

Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure

NCT00608140
View directory record Official record
Conditions
Mitral Valve Insufficiency, Heart Failure
Interventions
Surgical mitral valvuloplasty with placement of annular ring (SMVR), Optimal medical therapy (OMT)
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
8
States / cities
Atlanta, Georgia • Boston, Massachusetts • Minneapolis, Minnesota + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Oct 9, 2026, 5:53 AM EDT
Terminated No phase listed Observational

Left Ventricular Aneurysms in Children

NCT00268034
View directory record Official record
Conditions
Congenital Disorders
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 21 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 7, 2007 · Synced Oct 9, 2026, 5:53 AM EDT
Completed No phase listed Observational

Biomarkers for Detection of Brain Ischemia

NCT00490295
View directory record Official record
Conditions
Congenital Disorders
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
1 Day to 30 Days
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 27, 2013 · Synced Oct 9, 2026, 5:53 AM EDT
Terminated No phase listed Observational

Hepatitis C in Adults Who Underwent Congenital Heart Surgery Before Screening

NCT00359099
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1980 – 2006
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 27, 2013 · Synced Oct 9, 2026, 5:53 AM EDT
Terminated Phase 1 Interventional

Antithrombin III in Infants With Cardiopulmonary Bypass (CPB)

NCT01698567
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Antithrombin III, Placebo
Drug
Lead sponsor
University of Rochester
Other
Eligibility
1 Day to 180 Days
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2016 · Synced Oct 9, 2026, 5:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Risk Factors, Costs, and Impacts of ED Boarding

NCT07532564
View directory record Official record
Conditions
Stroke (CVA) or TIA, Diabetes, Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease), Sepsis, Hypertension, Heart Failure, Pneumonia, Urinary Tract Infection (Diagnosis), Chest Pain, Psychiatric Disorder, Sickle Cell Disease (SCD)
Interventions
Not listed
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
30,486 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 9, 2026, 5:53 AM EDT
Completed No phase listed Observational

Hypoxemia in Infants After Palliative Surgery

NCT00327977
View directory record Official record
Conditions
Congenital Disorders
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 3 Years
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2011
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Oct 9, 2026, 5:53 AM EDT
Completed No phase listed Observational

NIRS Predict Low Cardiac Output State in Neonates and Infants in Cardiac Surgery

NCT01849120
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
EQUANOX Advance 8004CB sensor
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
Up to 3 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 14, 2017 · Synced Oct 9, 2026, 5:53 AM EDT
Not yet recruiting No phase listed Observational

Observational Data Collection for Blood Hemoglobin Algorithm Validation in Pediatrics

NCT07706140
View directory record Official record
Conditions
Hemoglobin, Cerebral Oxygenation, Congenital Heart Disease
Interventions
Noninvasive hemoglobin monitoring
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Days to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 9, 2026, 5:53 AM EDT
Active, not recruiting Not applicable Interventional

Autus Valve Pivotal Study

NCT05006404
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Pulmonary Valve Replacement Surgery
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
18 Months to 16 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2036
U.S. locations
12
States / cities
Los Angeles, California • Aurora, Colorado • Atlanta, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 9, 2026, 5:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Follow Up on Freestyle Valves in Children

NCT00385112
View directory record Official record
Conditions
Right Ventricle, Pulmonary Valve Stenosis, Pulmonary Valve Atresia
Interventions
Echocardiogram
Procedure
Lead sponsor
Emory University
Other
Eligibility
8 Years to 40 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 26, 2017 · Synced Oct 9, 2026, 5:53 AM EDT