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ClinicalTrials.gov public records Last synced Sep 29, 2026, 4:41 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Surgical Anesthesia Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Prospective Trial of Alerting to Extended Hypotensive Exposures on Long-Term Outcome After Surgery

NCT02217969
View directory record Official record
Conditions
Anesthesia, Hypotension
Interventions
Electronic alert to SLUScore increase
Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 13, 2018 · Synced Sep 29, 2026, 4:41 AM EDT
Completed Not applicable Interventional Results available

Perioperative Intravenous Lidocaine or Epidural Anesthesia on Outcomes in Complex Spine Surgery

NCT00840996
View directory record Official record
Conditions
Spine Surgery
Interventions
Lidocaine, placebo
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 22, 2016 · Synced Sep 29, 2026, 4:41 AM EDT
Completed Not applicable Interventional Results available

A Comparison of Different Ventilation Strategies in Infants Using the PLMA™

NCT03235817
View directory record Official record
Conditions
Ventilation
Interventions
Spontaneous ventilation, Pressure support ventilation, Pressure control ventilation
Other · Device
Lead sponsor
Wake Forest University
Other
Eligibility
1 Month to 11 Months
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 17, 2022 · Synced Sep 29, 2026, 4:41 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Does Spinal Anesthesia for Prolapse Surgery With Lead to Urinary Retention?

NCT02547155
View directory record Official record
Conditions
Urinary Retention, Uterine Prolapse
Interventions
Spinal anesthesia, General anesthesia
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Apr 19, 2017 · Synced Sep 29, 2026, 4:41 AM EDT
Completed No phase listed Observational

POCD in Elderly Patients Following Desflurane or Sevoflurane General Anesthesia

NCT01199913
View directory record Official record
Conditions
1. Postoperative Cognitive Dysfunction
Interventions
The intervention will be Mini-Mental Status Examination (MMSE)
Other
Lead sponsor
Loma Linda University
Other
Eligibility
65 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2014 · Synced Sep 29, 2026, 4:41 AM EDT
Completed Phase 4 Interventional

Opioid Free Anesthesia and Bariatric Surgery

NCT04144153
View directory record Official record
Conditions
Postoperative Quality of Recovery
Interventions
Opioid Free Total Intravenous Anesthesia, Total Intravenous anesthesia with opioid
Combination Product
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 70 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 29, 2026, 4:41 AM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Effect of RECK in Posterior Spinal Fusion

NCT06447194
View directory record Official record
Conditions
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
Interventions
Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail, Placebo
Drug · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Sep 29, 2026, 4:41 AM EDT
Completed Not applicable Interventional

Cohort 2 Efficacy of Nasopharyngeal Ventilation With Endotracheal Tube for Surgery

NCT02018146
View directory record Official record
Conditions
General Anesthesia With Endotracheal Intubation in Surgery
Interventions
Mask then nasopharyngeal, Nasopharyngeal then mask
Other
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Sep 29, 2026, 4:41 AM EDT
Completed Phase 4 Interventional Results available

Serratus Plane Versus Paravertebral Nerve Blocks for Breast Surgery

NCT03860974
View directory record Official record
Conditions
Breast Surgery
Interventions
Serratus Plane block (single injection), Paravertebral block (single injection)
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 20, 2022 · Synced Sep 29, 2026, 4:41 AM EDT
Completed No phase listed Observational

Temperature Measurement in Post-Anesthesia Care Units

NCT00614588
View directory record Official record
Conditions
Surgery, Postoperative, Laparoscopic Surgery, General Anesthesia
Interventions
Body temperature thermometers
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 19, 2016 · Synced Sep 29, 2026, 4:41 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Effect of Methadone and Hydromorphone on the QT Interval After Anesthesia and Surgery

NCT03893734
View directory record Official record
Conditions
EKG-QT Prolongation
Interventions
methadone, Hydromorphone
Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 80 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Sep 29, 2026, 4:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Performance Assessment of the PMD-200 Under General Anesthesia

NCT03467230
View directory record Official record
Conditions
Pain, Opioid Use, Intraoperative Complications
Interventions
NoL Index
Device
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Sep 29, 2026, 4:41 AM EDT
Completed Not applicable Interventional

Protective Ventilation With Higher Versus Lower PEEP During General Anesthesia for Surgery in Obese Patients

NCT02148692
View directory record Official record
Conditions
Morbid Obesity, Surgery, General Anesthesia
Interventions
Higher PEEP, Lower PEEP
Procedure
Lead sponsor
Technische Universität Dresden
Other
Eligibility
18 Years and older
Enrollment
2,013 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 2, 2019 · Synced Sep 29, 2026, 4:41 AM EDT
Terminated No phase listed Interventional Results available

Validation of RPVi as a Parameter to Predict Fluid Responsiveness

NCT03706430
View directory record Official record
Conditions
Surgery, Anesthesia
Interventions
Pulse CO-Oximeter sensor
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 29, 2026, 4:41 AM EDT
Completed No phase listed Observational Results available

DBS Under General Anesthesia: Comparison To The Standard Technique

NCT01997398
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 31, 2015 · Synced Sep 29, 2026, 4:41 AM EDT
Recruiting Not applicable Interventional

Limiting Emergence Phenomena After General Anesthesia With Combined LMA and ETT Airway Management Technique

NCT02708836
View directory record Official record
Conditions
Limit Emergence Phenomena After General Anesthesia
Interventions
Induction of anesthesia, Placement of LMA [Ambu (R) AuraGain (TM) disposable laryngeal mask], Laryngoscopy and placement of ETT, Ventilation via the ETT, Removal of the ETT, Intubation of the trachea through the LMA, Ventilation via the LMA, Emergence from anesthesia
Procedure · Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 29, 2026, 4:41 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Safety and Efficacy of HSK3486 Compared to Propofol for Induction of General Anesthesia in Adults With Elective Surgery

NCT05486416
View directory record Official record
Conditions
General Anesthesia
Interventions
HSK3486, Propofol
Drug
Lead sponsor
Haisco-USA Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 99 Years
Enrollment
465 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
21
States / cities
Florence, Alabama • Sheffield, Alabama • Miami, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Sep 29, 2026, 4:41 AM EDT
Completed Not applicable Interventional

PROVHILO:Protective Ventilation During General Anesthesia for Open Abdominal Surgery

NCT01441791
View directory record Official record
Conditions
Postoperative Respiratory Complications
Interventions
Lung protective strategy ventilation
Procedure
Lead sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Boston, Massachusetts • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 8, 2014 · Synced Sep 29, 2026, 4:41 AM EDT
Terminated Not applicable Interventional Results available

The Effects of Corticosteroids, Glucose Control, and Depth-of-Anesthesia on Perioperative Inflammation and Morbidity From Major Non-cardiac Surgery (Dexamethasone, Light Anesthesia and Tight Glucose Control (DeLiT Trial))

NCT00995501
View directory record Official record
Conditions
Inflammation, Perioperative Morbidity
Interventions
Dexamethasone Sodium Sulfate, Insulin, anesthesia management, Dexamethasone - placebo, Insulin - Placebo, Anesthesia management -Placebo
Drug · Other
Lead sponsor
d sessler
Other
Eligibility
40 Years to 90 Years
Enrollment
381 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Sep 29, 2026, 4:41 AM EDT
Completed Phase 4 Interventional Results available

Effect of Fentanyl on Coughing and Recovery After Anesthesia With an LMA Laryngeal Mask Airway)for Airway Management

NCT01368809
View directory record Official record
Conditions
Ambulatory Surgery, Coughing
Interventions
Saline, Fentanyl
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2016 · Synced Sep 29, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Quadratus Lumborum Versus Transversus Abdominis Plane Nerve Block: A Comparison Study

NCT03490357
View directory record Official record
Conditions
Anesthesia
Interventions
Control - Transversus Abdominus Plane Block, Quadratus Lumborum Block
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Sep 29, 2026, 4:41 AM EDT
Not yet recruiting Not applicable Interventional

The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage

NCT07223866
View directory record Official record
Conditions
Cataract and IOL Surgery, Cataract Surgery Anesthesia, Cataract Surgery Experience, Nuclear Cataract
Interventions
High IOP Setting, Low IOP Setting
Device
Lead sponsor
Matthew Rauen
Other
Eligibility
60 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
West Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 29, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pre-op Use of Incentive Spirometry in Obese Patients

NCT01004146
View directory record Official record
Conditions
Lung Function, Bariatric Surgery
Interventions
Incentive Spirometry
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2014 · Synced Sep 29, 2026, 4:41 AM EDT
Terminated Phase 4 Interventional Results available

Liposomal Bupivacaine vs Peripheral Nerve Block

NCT03922620
View directory record Official record
Conditions
Pain, Acute, Surgery, Anesthesia, Opioid Use
Interventions
Liposomal bupivacaine, Peripheral Nerve Block
Drug
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Sep 29, 2026, 4:41 AM EDT