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ClinicalTrials.gov public records Last synced Oct 22, 2026, 1:35 AM EDT

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Showing 1–24 of 109 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Surgical Scar Clear all
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Surgical Dressing Study Comparing SYLKE vs Other Common Incisional Dressings Following Abdominoplasty/Panniculectomy Patients

NCT07878390
View directory record Official record
Conditions
Hypertrophic Surgical Scar, Medical Adhesive Related Skin Injury
Interventions
SYLKE, Dermabond Prineo, Paper Tape
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional

Pilot Study Investigating a Restorative Wound Care Cream Together With Petrolatum on Surgical Excisions

NCT04169438
View directory record Official record
Conditions
Wound Heal, Scar, Keloid, Surgical Wound
Interventions
Vehicle Cream Base Emulsion Moisturizer + Petrolatum, FS2 Emulsion Moisturizer + Petrolatum
Other
Lead sponsor
The Center for Clinical and Cosmetic Research
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Aventura, Florida
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery

NCT01346969
View directory record Official record
Conditions
Reduction in Hypertrophic Skin Scarring
Interventions
EXC 001
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
12
States / cities
Pasadena, California • Whittier, California • Lake Worth, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2021 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Phase 2 Interventional Results available

A Phase 2a Study to Evaluate the Safety and Efficacy of AZX100 in Trocar Sites of Arthroscopic Shoulder Surgery Patients

NCT00811577
View directory record Official record
Conditions
Scar Prevention, Scar Reduction
Interventions
Placebo, AZX100
Drug
Lead sponsor
Capstone Therapeutics
Industry
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
5
States / cities
Pasadena, California • DeLand, Florida • Orlando, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 11, 2012 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Phase 2 Interventional Results available

Study of GBT009 for Treatment of Incisional Wounds Following Breast Reconstruction Surgery

NCT01053897
View directory record Official record
Conditions
Scar Formation
Interventions
GBT009, Placebo
Biological
Lead sponsor
Garnet BioTherapeutics, Inc.
Industry
Eligibility
18 Years to 70 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Chicago, Illinois • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 24, 2013 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Results available

Pilot Study of a Novel 532nm KTP Laser for the Treatment of Fresh Surgical Scars

NCT01789346
View directory record Official record
Conditions
Scar, Surgical Scar, Cicatrix, Cicatrix, Hypertrophic, Keloid
Interventions
532nm KTP, 595nm PDL
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Safety and Efficacy of SLI-F06 in Wound Healing and Scar Appearance

NCT03880058
View directory record Official record
Conditions
Scars
Interventions
SLI-F06, Formulation buffer
Drug
Lead sponsor
Scarless Laboratories, Inc.
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
3
States / cities
Chicago, Illinois • St Louis, Missouri • Bala-Cynwyd, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dermabrasion in Mohs: Split-Scar Trial

NCT07213921
View directory record Official record
Conditions
Wound Heal
Interventions
Dermabrasion
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional

Mederma to Reduce Appearance of Post Surgical Scars

NCT01504061
View directory record Official record
Conditions
Scars
Interventions
Mederma N&I, Mederma Ultra Gel
Other
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2013 · Synced Oct 22, 2026, 1:35 AM EDT
Not listed Phase 1 Interventional

Study to Evaluate the Safety and Efficacy of Dermal Injections of JVS-100 Given to Adults Receiving Median Sternotomy

NCT01657045
View directory record Official record
Conditions
Median Sternotomy
Interventions
JVS-100 or placebo
Biological
Lead sponsor
SironRX Therapeutics, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
6
States / cities
Tampa, Florida • Chicago, Illinois • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2013 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Phase 4 Interventional

SurgiWrapTM to Reduce Soft Tissue Attachment & Incidence Early Post-Operative Bowel Obstruction in Colorectal Surgery

NCT00531739
View directory record Official record
Conditions
Adhesions, Colectomy
Interventions
Polylactic Acid Sheet
Other
Lead sponsor
Cytori Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2010 · Synced Oct 22, 2026, 1:35 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

Treatment of Breast Pain Using A Medication (Diclofenac) Applied to the Skin

NCT00276419
View directory record Official record
Conditions
Breast Pain, Non-cyclical Mastalgia, Surgical Scar-Related Breast Pain
Interventions
Diclofenac, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 20, 2012 · Synced Oct 22, 2026, 1:35 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparing 1 Week Versus 2 Week Cutaneous Suture Removal

NCT05267002
View directory record Official record
Conditions
Suture; Complications, Mechanical, Scar, Surgery
Interventions
Suture removal timing
Procedure
Lead sponsor
DermSurgery Associates
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2022 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Scar Results and Time for Closures of Scalp Defects Via Pulley Sutures or Layered Repairs

NCT02744950
View directory record Official record
Conditions
Scar
Interventions
Pulley stitches, Intermediate Repair
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 20, 2016 · Synced Oct 22, 2026, 1:35 AM EDT
Active, not recruiting Not applicable Interventional

Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects

NCT05074238
View directory record Official record
Conditions
Surgical Wound, Wound Heal, Wound of Skin, Scar
Interventions
Zinc containing suncreen
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 22, 2026, 1:35 AM EDT
Terminated Phase 4 Interventional Results available

Pregabalin for Abdominal Pain From Adhesions

NCT00310765
View directory record Official record
Conditions
Abdominal Pain, Surgical Adhesions
Interventions
Pregabalin 75 or 150 mg BID for 7 weeks followed by open label pregabalin 150 mg BID for 4 weeks, Placebo first followed by open label pregabalin
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
West Bloomfield, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Oct 22, 2026, 1:35 AM EDT
Completed No phase listed Observational

PMCF Study for COSEAL® in Gynecologic Surgery

NCT05996809
View directory record Official record
Conditions
Adhesion
Interventions
Coseal
Device
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Results available

Continuous Diffusion of Oxygen Treatment for Incision Wounds

NCT04307355
View directory record Official record
Conditions
Surgical Wound, Breast Surgery, Mammoplasty, Incision Wound
Interventions
Transcu O2®, Tegaderm, Silagen
Device · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Results available

Investigation of a Novel Silicone Dressing to Maximize the Outcomes of Scar Revision Procedures (IMPROVE)

NCT01430130
View directory record Official record
Conditions
Hypertrophic
Interventions
embrace device
Device
Lead sponsor
Neodyne Biosciences, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2014 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional

Aesthetic Outcome of Running Cuticular Suture Distance (2mm vs 5mm)

NCT04870008
View directory record Official record
Conditions
Suture, Dermatologic Surgery, Scar, Cosmetic Outcome
Interventions
Suture
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Force Modulating Tissue Bridges for Closure of Vertical Scars in Breast Reduction

NCT05028816
View directory record Official record
Conditions
Surgical Incision
Interventions
Side 1: Final layer closure with force modulating tissue bridges (FMTB), Side 1: Final layer dermal closure with poliglecaprone 25 suture, Side 2: Final layer closure with force modulating tissue bridges (FMTB), Side 2: Final layer dermal closure with poliglecaprone 25 suture
Device · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional

Comparison of Scar Formation in Syndactyly Release Surgery With Full Thickness Skin Graft Versus Skin Graft Substitute

NCT03107546
View directory record Official record
Conditions
Syndactyly
Interventions
Hyalomatrix, Skin graft
Device · Other
Lead sponsor
Gillette Children's Specialty Healthcare
Other
Eligibility
Up to 17 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Lasers in the Treatment of Scars

NCT02988622
View directory record Official record
Conditions
Scar
Interventions
Fraxel Laser, CO2 Laser
Device
Lead sponsor
Marta Hemmingson-Van Beek
Other
Eligibility
18 Years to 120 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 18, 2018 · Synced Oct 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional

Amniotic Membrane in Decompressive Craniectomy to Reduce Scarring

NCT02033824
View directory record Official record
Conditions
Scarring
Interventions
dHACM, Craniectomy
Other · Procedure
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Boulder, Colorado • Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 23, 2018 · Synced Oct 22, 2026, 1:35 AM EDT