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ClinicalTrials.gov public records Last synced Nov 7, 2026, 7:05 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 260 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Surgical Site Infection Clear all

Conditions: Ventral Hernia
Interventions: Group 1; Device
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 3
States / cities: Asheville, North Carolina • Charlotte, North Carolina • Greenville, South Carolina

Conditions: Abdominal Wall Wound
Interventions: Dressing removal at 24 hours, Dressing removal at 48 hours; Other
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 869 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Benign Pancreatic Neoplasm, Malignant Pancreatic Neoplasm
Interventions: Biospecimen Collection, Laboratory Procedure, Nanopore Sequencing; Procedure · Other · Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Appendicitis (Diagnosis)
Interventions: Cefoxitin; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Surgical Site Infection
Interventions: Clindamycin 1% Gel, Benzoyl peroxide 5% gel, BenzaClin 5%-1% Topical Gel; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Surgical Site Infection, Zonulin
Interventions: Zonulin Biomarker; Diagnostic Test
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Chlorhexidine Gluconate Cloths, Infection; Cesarean Section, Infectious Morbidity, Surgical Site Infections, Endometritis
Interventions: 2% chlorhexidine gluconate (CHG) cloth, Placebo cloth; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1,356 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Surgical Wound Infection
Interventions: Negative Pressure Wound Therapy; Device
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 290 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Bacterial Infections
Interventions: ceftaroline, vancomycin plus aztreonam, Placebo; Drug
Lead sponsor: Forest Laboratories; Industry
Eligibility: 18 Years and older
Enrollment: 680 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007
U.S. locations: 17
States / cities: Buena Park, California • Hawaiian Gardens, California • Los Angeles, California + 14 more

Conditions: Anxiety, Pain, Surgical Site Infection
Interventions: cellular device/computers; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Surgical Site Infection, Surgical Wound Infection, Cesarean Section; Infection, Cesarean Section Complications
Interventions: Vicryl-plus, monocryl-plus, PDS-plus (Triclosan-coated Sutures), Vicryl, monocryl, PDS (not coated with triclosan); Drug · Other
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 1,169 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Surgical Site Infection, Surgical Complication, Implant Infection, Implant Complication
Interventions: Xperience™ Advanced Surgical Irrigation, Dilute Povidone-Iodine; Device
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older · Female only
Enrollment: 224 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Hypovitaminosis D
Interventions: Cholecalciferol, Placebo; Dietary Supplement
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 100 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Abscess, Wound Infection, Surgical Site Infection, Cellulitis
Interventions: Dalbavancin, Dalbavancin-matching Placebo; Drug
Lead sponsor: Durata Therapeutics Inc., an affiliate of Allergan plc; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 698 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 25
States / cities: Montgomery, Alabama • Anaheim, California • Long Beach, California + 18 more

Conditions: Surgical Site Infection
Interventions: 3M Skin and Nasal Antiseptic; Drug
Lead sponsor: 3M; Industry
Eligibility: 2 Years and older
Enrollment: 333 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: San Diego, California

Conditions: Surgical Wound Infection, Spinal Deformity, Spinal Degeneration
Interventions: Antibiotic Protocol; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 539 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Post-operative Complications, Surgical Site Infection, Surgical Wound Infection
Interventions: Prevena™ Incision Management System (PIMS), Standard-of-care Dressing; Device
Lead sponsor: KCI USA, Inc; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Surgical Site Infection
Interventions: Chlorhexidine - Isopropyl alcohol, Povidone-Iodine Scrub and Paint; Drug
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 932 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Infection Control, Surgical Site Infection
Interventions: Intervention Cluster; Other
Lead sponsor: Duke University; Other
Eligibility: Not listed
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Late Effects of Surgery, Staphylococcus Aureus, Surgical Site Infection
Interventions: daptomycin; Drug
Lead sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center; Other
Eligibility: 19 Years to 74 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Torrance, California

Conditions: Breast Cancer
Interventions: Chlorhexidine irrigation, triple antibiotic irrigation; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 81 Years · Female only
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Surgical Site Infection
Interventions: Cephalexin, Placebo, Metronidazole; Drug
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 321 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 2
States / cities: Austin, Texas • Galveston, Texas

Conditions: Surgical Wound Infections, Colorectal Surgery
Interventions: standard operating management; Procedure
Lead sponsor: Dallas VA Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 197 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Surgical Site Infection, Surgical Complication, Gynecologic Cancer
Interventions: Diagnosed with Surgical Site Infection; Other
Lead sponsor: WellSpan Health; Other
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 778 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: York, Pennsylvania

Search by objective public record fields.

Microlyte in Prevention of SSI After Open Ventral Hernia Repair

Impact of Timing of Wound Dressing Removal After Cesarean Section

"Answers in Hours" A Randomized Controlled Trial Using Microbiome Metagenomics for Bile Duct Cultures

Precision Antibiotic Dosing for Appendectomy

Topical Treatment and Prevalence of P. Acnes

Zonulin Biomarker for Diagnosis of Hip and Knee Infections

STRIPES Study: Study To Reduce Infection Post cEsarean Section

NPWT in Patients Undergoing Surgical Procedures for Management of GI Malignancies

Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections

Text Message Study

Antibacterial-coated Sutures at Time of Cesarean

A Novel Surgical Irrigation Solution in Post-Mastectomy Reconstruction: Evaluating Xperience™

Vitamin D Status in Lower Extremity Joint Replacement Surgery Patients

Single Dose vs. Two Dose Regimen of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Impact of Pre-surgical Nasal Bacterial Reduction on Postoperative Surgical Site Infections / Standard Care Change

Comparison of Antibiotic Protocols in Spine Patients With Postoperative Drains

The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions

Chlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis

Early Recognition and Response to Increases in Surgical Site Infections Using Optimized Statistical Process Control Charts: The Early 2RIS Study

Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass Surgery

Surgical Site Infection With 0.05% Chlorhexidine (CHG) Compared to Triple Antibiotic Irrigation

Prophylactic Antibiotics After Cesarean

Minimization of Surgical Site Infections for Pts Undergoing Colorectal Surgery

Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery