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ClinicalTrials.gov public records Last synced Oct 3, 2026, 8:52 AM EDT

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Showing 25–48 of 313 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Surgical Wound Infections Clear all
Completed No phase listed Observational

Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys

NCT02032030
View directory record Official record
Conditions
Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation, Angina, Deep Vein Thrombosis, Pulmonary Embolism, Respiratory Arrest, Respiratory Failure, Pneumonia, Gastrointestinal Bleed, Stomach Ulcer, Delirium, Stroke, Nerve Injury, Surgical Wound Infection
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
73,952 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Phase 2 Interventional

Nasal Photodisinfection in All Patients Presenting for Surgery for a Wide Range of Surgical Procedures

NCT05090657
View directory record Official record
Conditions
Surgical Site Infections, Nosocomial Infection, Healthcare Associated Infections
Interventions
methylene blue 0.01%/chlorhexidine gluconate 0.25% + light activation
Combination Product
Lead sponsor
Ondine Biomedical Inc.
Industry
Eligibility
18 Years and older
Enrollment
322 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Savannah, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Phase 3 Interventional Results available

A Study of an Antibiotic Implant in General Surgical Subjects at Higher Risk for Surgical Wound Infection

NCT00600925
View directory record Official record
Conditions
Colorectal Surgery, Surgical Wound Infection
Interventions
gentamicin-collagen sponge dipped in saline
Drug
Lead sponsor
Innocoll
Industry
Eligibility
18 Years and older
Enrollment
602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
39
States / cities
Florence, Alabama • Mobile, Alabama • Laguna Hills, California + 36 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2021 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Phase 1 Interventional

Prophylactic Antibiotics After Cesarean

NCT03187106
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Cephalexin, Placebo, Metronidazole
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Austin, Texas • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 16, 2023 · Synced Oct 3, 2026, 8:52 AM EDT
Terminated Not applicable Interventional Results available

Topical Silver for Prevention of Wound Infection After Cesarean Delivery

NCT01169064
View directory record Official record
Conditions
Wound Infection
Interventions
Silver-containing surgical dressing, Cloth adhesive dressing
Device
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
475 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Not applicable Interventional Results available

Study Looking at the Effect of Silverlon on Post Operative Wound Infections

NCT01143883
View directory record Official record
Conditions
Infections, Surgery
Interventions
Silverlon, Standard of Care Dressing
Other
Lead sponsor
Jorge Marcet
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 13, 2013 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Not applicable Interventional

Interventional Study Exploring the Occurrence of Surgical Site Infections.

NCT06661473
View directory record Official record
Conditions
Total Knee Arthroplasty, Total Hip Arthroplasty Revision, Total Knee Arthroplasty Revision
Interventions
Avance Solo Negative Pressure Wound Therapy
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
8
States / cities
Washington D.C., District of Columbia • Indianapolis, Indiana • Baltimore, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Phase 4 Interventional

Negative Pressure Therapy for Groin Wounds

NCT02954835
View directory record Official record
Conditions
Wound Infection
Interventions
Prevena, Traditional Dressing
Device
Lead sponsor
Englewood Hospital and Medical Center
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Englewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 3, 2026, 8:52 AM EDT
Terminated Phase 4 Interventional Results available

Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage

NCT01673061
View directory record Official record
Conditions
Abscess
Interventions
Lidocaine, Vapocoolant
Drug
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 19, 2020 · Synced Oct 3, 2026, 8:52 AM EDT
Terminated Not applicable Interventional

Chlorhexidine and/or Betadine Prep in Pediatric Arm Surgery Following Trauma

NCT04225065
View directory record Official record
Conditions
Arm Fracture, Surgical Site Infection
Interventions
Chlorhexidine, Betadine
Other
Lead sponsor
Geisinger Clinic
Other
Eligibility
Up to 10 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 27, 2024 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Not applicable Interventional

SUpPress SSI - Single Use Negative Pressure Wound Therapy (NPWT) to Reduce Surgical Site Infections

NCT03816293
View directory record Official record
Conditions
Surgical Site Infection, Obesity, Diabetes, Cesarean Section Complications
Interventions
Negative Pressure Wound Therapy
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
3,680 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
5
States / cities
Atlanta, Georgia • Chicago, Illinois • Iowa City, Iowa + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Not applicable Interventional

Efficacy of Surgical Diathermy in Eradicating Cutibacterium Acnes From Surgical Skin Incision During Shoulder Arthroplasty

NCT04608916
View directory record Official record
Conditions
Infection, Bacterial
Interventions
Using surgical diathermy to make skin incision, Using scalpel blade to make skin incision
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older · Male only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Not applicable Interventional Results available

Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection

NCT02020018
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Prevena Incision Management System, Conventional sterile dry wound dressing
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
1,869 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 6, 2019 · Synced Oct 3, 2026, 8:52 AM EDT
Terminated Not applicable Interventional

Prevention of Infection in Closed Fractures: Cefazolin Versus Vancomycin

NCT02027532
View directory record Official record
Conditions
Infection, Closed Fractures
Interventions
Cefazolin, Vancomycin
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 85 Years
Enrollment
430 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Not applicable Interventional Results available

Continuous Diffusion of Oxygen Treatment for Incision Wounds

NCT04307355
View directory record Official record
Conditions
Surgical Wound, Breast Surgery, Mammoplasty, Incision Wound
Interventions
Transcu O2®, Tegaderm, Silagen
Device · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Primary Plating in Sternotomy Patients for Osteosynthesis and Pain

NCT00819286
View directory record Official record
Conditions
Sternal Wound Infection, Sternal Non-union, Pain, Mediastinitis
Interventions
SternaLock Rigid Fixation Plates, wire (control)
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
5
States / cities
Phoenix, Arizona • Sacramento, California • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Oct 3, 2026, 8:52 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Effect of Forced Air Warming During Cesarean Section on Postoperative Infectious Morbidity

NCT00696462
View directory record Official record
Conditions
Cesarean Section
Interventions
forced-air warming
Device
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 13, 2012 · Synced Oct 3, 2026, 8:52 AM EDT
Terminated Not applicable Interventional

AO Multicenter Intervention Trial for Prevention of Surgical Site Infection

NCT03380273
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Implementation of the AO Trauma SSI Prevention Bundle
Behavioral
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
18 Years to 100 Years
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
8
States / cities
Los Angeles, California • Lexington, Kentucky • Worcester, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Phase 4 Interventional Results available

Povidone-Iodine for Nasal Decolonization

NCT05529173
View directory record Official record
Conditions
Surgical Wound Infection, Preoperative Care, Methicillin-Resistant Staphylococcus Aureus
Interventions
Povidone-Iodine 10%, 0.9% NaCl Solution
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 80 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 13, 2024 · Synced Oct 3, 2026, 8:52 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Zinc Oxide Versus Petrolatum Following Skin Surgery

NCT03561376
View directory record Official record
Conditions
Surgical Incision, Surgery--Complications, Surgical Wound, Surgical Site Infection, Scar, Hypertrophic Scar
Interventions
Topical zinc oxide vs. petrolatum post-surgical scars
Drug
Lead sponsor
Melissa Pugliano-Mauro
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Pittsburgh, PA, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 3, 2026, 8:52 AM EDT
Withdrawn Not applicable Interventional

Prevention of Surgical Site Infection After Cesarean Delivery

NCT02027324
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Chlorhexidine-alcohol group, Povidone-Iodine Group
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 12, 2016 · Synced Oct 3, 2026, 8:52 AM EDT
Recruiting No phase listed Observational

Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients

NCT06378359
View directory record Official record
Conditions
Staphylococcus Aureus Colonization, Surgical Site Infections, Healthcare Associated Infections
Interventions
Screening and decolonization for SA carriers with the 3 drug bundle, No screening for SA, no screening, Nasal povidone-iodine on surgery day plus 2 CHG pre-op showers without screening., Nasal alcohol gel on surgery day plus 2 CHG pre-op showers without screening
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 3, 2026, 8:52 AM EDT
Completed Not applicable Interventional

The Effect of Timing of Removal of Wound Dressing on Surgical Site Infection Rate After Cesarean Delivery

NCT02902419
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Wound dressing removal.
Other
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Albany, New York • Niskayuna, New York
Source: ClinicalTrials.gov public record
Updated Sep 15, 2016 · Synced Oct 3, 2026, 8:52 AM EDT
Completed No phase listed Observational Results available

Topical Antibiotic Treatment for Spine Surgical Site Infection

NCT02776774
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Oct 3, 2026, 8:52 AM EDT