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Showing 1–24 of 734 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Swallowing Clear all
Recruiting Phase 2 Interventional

Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease

NCT06638944
View directory record Official record
Conditions
Dysphagia, Stroke, Parkinson Disease
Interventions
In-person sEMG-biofeedback, Remote sEMG-biofeedback, Standard-of-care treatment
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
50 Years to 90 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Champaign, Illinois • West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 4, 2026, 11:11 PM EDT
Withdrawn Phase 2 Interventional

Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery

NCT03488147
View directory record Official record
Conditions
Dysphagia, GERD, Degenerative Joint Disease
Interventions
Esomeprazole, Placebo Oral Tablet
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 22, 2020 · Synced Sep 4, 2026, 11:11 PM EDT
Not listed No phase listed Observational

Quality of Life Assessment of Cryotherapy in Esophageal or Gastroesophageal Cancer

NCT03285035
View directory record Official record
Conditions
Esophageal Cancer
Interventions
Administration of questionaires to patients receiving an upper endoscopy with cryotherapy in addition to chemotherapy for esophageal cancer palliation.
Device
Lead sponsor
Western Regional Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
50 participants
Timeline
2017 – 2021
U.S. locations
1
States / cities
Goodyear, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 10, 2019 · Synced Sep 4, 2026, 11:11 PM EDT
Completed Not applicable Interventional Results available

A Clinical Trial of Proton Pump Inhibitors to Treat Children With Chronic Otitis Media With Effusion

NCT00546117
View directory record Official record
Conditions
Otitis Media With Effusion
Interventions
lansoprazole, placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
2 Years to 12 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced Sep 4, 2026, 11:11 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects

NCT01557920
View directory record Official record
Conditions
Airway Complication of Anaesthesia, Healthy
Interventions
Propofol, Sevoflurane
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 12, 2016 · Synced Sep 4, 2026, 11:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Measuring Pharyngeal Muscle Improvements Following Behavioral Swallowing Exercises

NCT05080725
View directory record Official record
Conditions
Dysphagia
Interventions
TelePEPP intervention
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
65 Years to 120 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Sep 4, 2026, 11:11 PM EDT
Completed No phase listed Observational

Quality of Life After Esophagectomy for Cancer

NCT00798746
View directory record Official record
Conditions
Esophageal Cancer
Interventions
Telephone Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2012 · Synced Sep 4, 2026, 11:11 PM EDT
Completed Not applicable Interventional

Comparing FEES to VFSS in Diagnosing Laryngeal Penetration and Aspiration in Infants in the NICU

NCT02003287
View directory record Official record
Conditions
Deglutition Disorders
Interventions
VFSS, FEES
Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
37 Weeks and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2015 · Synced Sep 4, 2026, 11:11 PM EDT
Terminated Phase 2 Interventional Results available

Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia

NCT00503776
View directory record Official record
Conditions
Dysphagia, Head and Neck Cancer, Mucositis, Xerostomia
Interventions
exercise intervention, amifostine trihydrate, therapeutic dietary intervention
Behavioral · Drug · Procedure
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
21 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Sep 4, 2026, 11:11 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Autologous Muscle Derived Cells for Treatment of Tongue Dysphagia

NCT05421689
View directory record Official record
Conditions
Oropharyngeal Dysphagia
Interventions
Autologous Muscle Derived Cells for Gastro-Intestinal Repair (AMDC-GIR), Placebo
Biological · Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Sacramento, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Sep 4, 2026, 11:11 PM EDT
Completed Phase 2 Interventional Results available

A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Dysphagia

NCT00376506
View directory record Official record
Conditions
Chronic Dysphagia, Multiple Sclerosis, Parkinson Disease
Interventions
Neurostimulation device for dysphagia, External vibrotactile device
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 25, 2012 · Synced Sep 4, 2026, 11:11 PM EDT
Completed Not applicable Interventional

A Comparison of the Blom Low Profile Voice Inner Cannula and the Passy-Muir One-Way Tracheotomy Tube Speaking Valve on Voice Production, Speech Intelligibility, and Biomechanical Swallowing Behavior

NCT01784224
View directory record Official record
Conditions
Mechanical Complication of Tracheostomy
Interventions
Blom Low Profile Voice Cannula/Passty-Muir Speaking Valves
Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 12, 2014 · Synced Sep 4, 2026, 11:11 PM EDT
Active, not recruiting Phase 1 Interventional

A Trial of a New Type of Photodynamic Therapy (VTP) in the Treatment of Patients With Cancer of the Esophagus Who Have Trouble Swallowing

NCT03133650
View directory record Official record
Conditions
Esophagogastric Cancer, Moderate to Severe Dysphagia
Interventions
WST 11-mediated VTP therapy
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 4, 2026, 11:11 PM EDT
Terminated Phase 3 Interventional

Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects

NCT00000362
View directory record Official record
Conditions
Pneumonia, Aspiration
Interventions
Chin-down position, Thickened liquid administration
Behavioral
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
50 Years to 95 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2006
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 23, 2006 · Synced Sep 4, 2026, 11:11 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

To Determine if Sleep Deprivation Results in Increased Esophageal Acid Exposure

NCT01093339
View directory record Official record
Conditions
Gastroesophageal Disease
Interventions
Not listed
Lead sponsor
Southern Arizona VA Health Care System
Federal
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 18, 2010 · Synced Sep 4, 2026, 11:11 PM EDT
Withdrawn Phase 2 Interventional

Prospective Evaluation of a New Covered Metal Stent for Malignant Lesions of the Esophagus

NCT01301495
View directory record Official record
Conditions
Esophageal Cancer
Interventions
HANAROSTENT TM covered Esophageal Stent
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Sep 4, 2026, 11:11 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Progression of Gastroesophageal Reflux Disease and Barrett's Esophagus and the Creation of a Barrett's Registry

NCT00574327
View directory record Official record
Conditions
Barrett's Esophagus, Gastroesophageal Reflux Disease, Esophageal Adenocarcinoma
Interventions
Not listed
Lead sponsor
Midwest Biomedical Research
Other
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2029
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 15, 2023 · Synced Sep 4, 2026, 11:11 PM EDT
Terminated Phase 2 Interventional

Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma

NCT02225496
View directory record Official record
Conditions
Oropharyngeal Cancer
Interventions
Transoral Robotic Surgery (TORS), Modified Barium Swallow (MBS), Questionnaires
Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 14, 2017 · Synced Sep 4, 2026, 11:11 PM EDT
Suspended No phase listed Observational

Narrow Band Imaging Project on Barrett's Esophagus

NCT01580631
View directory record Official record
Conditions
Barrett's Esophagus, Gastroesophageal Reflux Disease
Interventions
Not listed
Lead sponsor
Midwest Biomedical Research
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2025
U.S. locations
2
States / cities
Chicago, Illinois • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 15, 2023 · Synced Sep 4, 2026, 11:11 PM EDT
Terminated No phase listed Observational

Registry to Compare Two Surgical Treatments for GERD

NCT02211105
View directory record Official record
Conditions
GastroEsophageal Reflux Disease
Interventions
Not listed
Lead sponsor
American Gastroenterological Association
Other
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
10
States / cities
Huntington Beach, California • Englewood, Colorado • Chicago, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2018 · Synced Sep 4, 2026, 11:11 PM EDT
Not yet recruiting No phase listed Observational

REVIVE Prospective Registry Cohort Study

NCT07429890
View directory record Official record
Conditions
Oropharyngeal Dysphagia
Interventions
Other: No Intervention (subjects were previously treated with Iltamiocel). This is a observational study and all participants will be observed with no intervention.
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
2
States / cities
Sacramento, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 4, 2026, 11:11 PM EDT
Completed No phase listed Observational

Post Extubation Dysphagia

NCT01849679
View directory record Official record
Conditions
Severity of Aspiration in Post-extubated Subjects
Interventions
Evaluation of Swallowing
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 31, 2016 · Synced Sep 4, 2026, 11:11 PM EDT
Terminated Phase 3 Interventional Results available

A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)

NCT03561090
View directory record Official record
Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
IW-3718, placebo, Standard-dose PPIs QD
Drug
Lead sponsor
Ironwood Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
495 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
93
States / cities
Anniston, Alabama • Mobile, Alabama • Phoenix, Arizona + 81 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2021 · Synced Sep 4, 2026, 11:11 PM EDT
Completed Not applicable Interventional Results available

Patient Acceptance and Preference Among Screening Modalities for Detection of Barrett's Esophagus

NCT04301986
View directory record Official record
Conditions
Barrett Esophagus, GERD
Interventions
Cytosponge, Transnasal Endoscopy (TNE), Esophagogastroduodenoscopy
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 7, 2023 · Synced Sep 4, 2026, 11:11 PM EDT