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ClinicalTrials.gov public records Last synced Oct 31, 2026, 2:03 PM EDT

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Showing 433–456 of 738 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Swallowing Clear all
Active, not recruiting Phase 1Phase 2 Interventional

Autologous Muscle Derived Cells for Treatment of Tongue Dysphagia

NCT05421689
View directory record Official record
Conditions
Oropharyngeal Dysphagia
Interventions
Autologous Muscle Derived Cells for Gastro-Intestinal Repair (AMDC-GIR), Placebo
Biological · Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Sacramento, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 31, 2026, 2:03 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Dysphagia Following Anterior Cervical Spine Surgery; Single Dose Steroid vs Saline (DysDexVSSal)

NCT03711474
View directory record Official record
Conditions
Dysphagia
Interventions
Dexamethasone, Saline
Drug
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 80 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Oct 31, 2026, 2:03 PM EDT
Completed Not applicable Interventional

Per-Oral Endoscopic Esophagomyotomy (POEM)

NCT01635374
View directory record Official record
Conditions
Achalasia
Interventions
Per-Oral Endoscopic Esophagomyotomy
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 85 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 6, 2015 · Synced Oct 31, 2026, 2:03 PM EDT
Completed No phase listed Observational

Post Extubation Dysphagia

NCT01849679
View directory record Official record
Conditions
Severity of Aspiration in Post-extubated Subjects
Interventions
Evaluation of Swallowing
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 1, 2016 · Synced Oct 31, 2026, 2:03 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Per-Oral Endoscopic Myotomy (POEM) for the Treatment of Achalasia, Database Repository

NCT02770859
View directory record Official record
Conditions
Achalasia
Interventions
POEM (Per Oral Endoscopic Myotomy)
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2040
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 31, 2026, 2:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

No Post Intubation Laryngeal Symptoms

NCT05383417
View directory record Official record
Conditions
Sore-throat, Dysphonia, Dysphagia, Intubation Complication, Anesthesia Intubation Complication, Anesthesia Morbidity, Anesthesia Complication, Anesthesia; Adverse Effect, Anesthesia; Reaction, Throat Disorder, Throat; Wound, Throat Injury
Interventions
EndoClip
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 31, 2026, 2:03 PM EDT
Recruiting No phase listed Observational

The Role of Laryngopharyngeal Reflux in IPF

NCT03418350
View directory record Official record
Conditions
IPF, Reflux
Interventions
Not listed
Lead sponsor
National Jewish Health
Other
Eligibility
40 Years to 95 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 14, 2024 · Synced Oct 31, 2026, 2:03 PM EDT
Completed Not applicable Interventional Results available

Pill Swallow Study

NCT04911296
View directory record Official record
Conditions
Not Determined
Interventions
Mock-RP
Other
Lead sponsor
RANI Therapeutics
Industry
Eligibility
21 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Oct 31, 2026, 2:03 PM EDT
Terminated Not applicable Interventional

Per-Oral Endoscopic Myotomy for Esophageal Swallowing Disorders

NCT02482337
View directory record Official record
Conditions
Achalasia
Interventions
POEM
Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 31, 2026, 2:03 PM EDT
Completed Not applicable Interventional

Randomized Controlled Trial of Endoscopic Dilation: Triamcinolone Injection

NCT01873573
View directory record Official record
Conditions
Dysphagia
Interventions
Dilation, Triamcinolone Injection, Esophagogastroduodenoscopy (EGD)
Procedure · Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 24, 2017 · Synced Oct 31, 2026, 2:03 PM EDT
Completed Phase 1 Interventional

GCC Agonist Signal in the Small Intestine

NCT05107219
View directory record Official record
Conditions
Barrett Esophagus, Gastroesophageal Reflux Disease, Malignant Digestive System Neoplasm
Interventions
Biopsy, Biospecimen Collection, Esophagogastroduodenoscopy, Linaclotide, Plecanatide
Procedure · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Scottsdale, Arizona • Philadelphia, Pennsylvania • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 31, 2026, 2:03 PM EDT
Completed No phase listed Observational Results available

The Passy Muir Swallowing Self Training Device

NCT01765673
View directory record Official record
Conditions
Oropharyngeal Dysphagia
Interventions
Vibrotactile stimulation
Device
Lead sponsor
James Madison University
Other
Eligibility
20 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Harrisonburg, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 14, 2017 · Synced Oct 31, 2026, 2:03 PM EDT
Completed Phase 3 Interventional Results available

Study Evaluating the Efficacy and Safety of Pantoprazole in Infants With Symptomatic Gastroesophageal Reflux Disease (GERD)

NCT00365300
View directory record Official record
Conditions
Gastroesophageal Reflux
Interventions
pantoprazole, Placebo
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
28 Days to 11 Months
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
38
States / cities
Mobile, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 35 more
Source: ClinicalTrials.gov public record
Updated May 4, 2010 · Synced Oct 31, 2026, 2:03 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Effect of PPI Therapy on Weight, Gut Microbiome, and Expression of GPR41 and GPR43

NCT02457104
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Obesity
Interventions
Colonoscopy, Weight and diet questionnaire
Procedure · Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years to 59 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 18, 2021 · Synced Oct 31, 2026, 2:03 PM EDT
Terminated Not applicable Interventional

Rubber Band Ligation and Mucosectomy for Gastroesophageal Reflux Disease (GERD)

NCT01199679
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Heartburn, Regurgitation, Dyspepsia
Interventions
Mucosectomy, Rubber Band Ligation
Procedure
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 19, 2015 · Synced Oct 31, 2026, 2:03 PM EDT
Terminated Not applicable Interventional

Effects of Swallowing Exercises on Patients Undergoing Radiation Treatment for Head and Neck Cancer

NCT01053546
View directory record Official record
Conditions
Head and Neck Cancer, Stage I Hypopharyngeal Cancer, Stage I Laryngeal Cancer, Stage I Oropharyngeal Cancer, Stage II Hypopharyngeal Cancer, Stage II Laryngeal Cancer, Stage II Oropharyngeal Cancer, Stage III Hypopharyngeal Cancer, Stage III Laryngeal Cancer, Stage III Oropharyngeal Cancer, Stage IV Hypopharyngeal Cancer, Stage IV Laryngeal Cancer, Stage IV Oropharyngeal Cancer
Interventions
exercise intervention, questionnaire administration, quality-of-life assessment
Behavioral · Other · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Oct 31, 2026, 2:03 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Exparel as a Nerve Block for Severe Hand Pain

NCT02374320
View directory record Official record
Conditions
CREST Syndrome, Peripheral Vascular Disease, Raynaud Disease, Scleroderma, Diffuse
Interventions
liposomal bupivacaine
Drug
Lead sponsor
Jose Soberon, MD
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 31, 2026, 2:03 PM EDT
Completed Not applicable Interventional

Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease

NCT02890979
View directory record Official record
Conditions
Barrett Esophagus, Dysplasia, Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma, Gastroesophageal Reflux Disease, Metaplasia
Interventions
Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Swallowable Sponge Cell Sampling Device
Other · Device
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 25, 2020 · Synced Oct 31, 2026, 2:03 PM EDT
Completed Phase 2 Interventional Results available

Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia

NCT01085903
View directory record Official record
Conditions
Spatial Neglect, Dysphagia
Interventions
Modafinil, Placebo, Baseline, CPS, Post CPS, Follow up
Drug · Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
19 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
Conway, Arkansas • Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Oct 31, 2026, 2:03 PM EDT
Completed Not applicable Interventional Results available

Patient Acceptance and Preference Among Screening Modalities for Detection of Barrett's Esophagus

NCT04301986
View directory record Official record
Conditions
Barrett Esophagus, GERD
Interventions
Cytosponge, Transnasal Endoscopy (TNE), Esophagogastroduodenoscopy
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Oct 31, 2026, 2:03 PM EDT
Terminated No phase listed Observational

Online Parent-Report Evaluation of the Effects of Processed Music

NCT05249270
View directory record Official record
Conditions
Sensory Disorders, Sensory Processing Disorder, Autism Spectrum Disorder, Eating Disorders, Gastro-Intestinal Disorder, Swallowing Disorder, Anxiety
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
132 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Woodinville, Washington
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Oct 31, 2026, 2:03 PM EDT
Completed Not applicable Interventional

Comparative Anti-Reflux Procedures in Neurologically Impaired Children

NCT01307982
View directory record Official record
Conditions
Gastroesophageal Reflux, Nervous System Diseases, Fundoplication, Enteral Nutrition
Interventions
Fundoplication, Gastrojejunal (GJ) feeding tube
Procedure
Lead sponsor
University of Utah
Other
Eligibility
6 Months to 18 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 21, 2013 · Synced Oct 31, 2026, 2:03 PM EDT
Completed No phase listed Observational

Scleroderma Lung: Role of Gastroesophageal Reflux, Microaspiration and Cough

NCT01667042
View directory record Official record
Conditions
Scleroderma Lung
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 8, 2016 · Synced Oct 31, 2026, 2:03 PM EDT
Terminated Not applicable Interventional Results available

An Investigation of the EndoStim® Lower Esophageal Sphincter (LES) Stimulation System for the Treatment of Reflux

NCT02749071
View directory record Official record
Conditions
Gastroesophageal Reflux Disease (GERD), Reflux, Gastroesophageal, Gastroesophageal Reflux, Acid Reflux
Interventions
Laparoscopic implantation surgery with or without crural repair, EndoStim stimulation for first six months of study, EndoStim stimulation from Month 6 thru end of study, Sham EndoStim stimulation for first six months of study
Procedure · Device
Lead sponsor
EndoStim Inc.
Industry
Eligibility
22 Years to 75 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
18
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Los Angeles, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 31, 2026, 2:03 PM EDT