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Showing 1561–1584 of 8,851 matching trials from the live ClinicalTrials.gov search.
Recruiting Phase 2 Interventional Accepts healthy volunteers

Semaglutide for Post-Smoking Cessation Weight Management

NCT06173778
Conditions
Obesity, Overweight, Cigarette Smoking
Interventions
semaglutide 2.4mg, Placebo, Nicotine Replacement Therapy (NRT, nicotine patch), Brief Smoking Cessation Counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
197 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Austin, Texas • Houston, Texas
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Functional Capacity in Older Adults With Short Session High Intensity Interval Training

NCT03750006
Conditions
Frailty
Interventions
Short session HIIT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 85 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Stress Disorders, Post-Traumatic, Anxiety, Depression
Interventions
Trauma-focused cognitive behavioral therapy (TF-CBT), Child-centered supportive therapy (CCT)
Behavioral
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
7 Years to 14 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Testing a Non-Deceptive Placebo Intervention for Subclinical Depressive Symptoms

NCT07889908
Conditions
Depression - Major Depressive Disorder, Psychological Distress, Depression / Major Depressive Disorder
Interventions
Non-deceptive placebo (NDP)
Other
Lead sponsor
Miami University
Other
Eligibility
18 Years to 30 Years
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Oxford, Ohio
Conditions
Stress, Caregiver Burden, Anxiety, Depressive Symptoms
Interventions
Self-Compassion Based Resilient Caregiving Course
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Depression
Interventions
TIP
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
65 Years and older
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Ann Arbor, Michigan • New York, New York
Suspended Not applicable Interventional

The Milk, Growth and Microbiota Study

NCT03220282
Conditions
Preterm Infant, Growth Delay, Microbial Colonization, Breastfeeding, Breast Milk Substitute Intolerance
Interventions
Donor milk, Preterm infant formula
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
1 Hour to 96 Hours
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
San Francisco, California
Conditions
Problem Behaviors, Attention Deficit Hyperactivity Disorder, Depression
Interventions
Attachment and Biobehavioral Catch-up, Developmental Education for Families
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
20 Months to 36 Months
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2016
U.S. locations
1
States / cities
Newark, Delaware
Conditions
Physical Activity Levels, Cardiovascular Fitness, Body Composition, Situational Motivation, Situational Interest, Mood States, Depressive Symptoms
Interventions
VR-based exercise bike, Usual routine
Device · Other
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 35 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers

Coached or Non-Coached Weight Loss Intervention

NCT04645108
Conditions
Obesity, Behavior, Health, Behavior, Eating, Weight Loss, Overweight and Obesity, Self Efficacy
Interventions
Noom Healthy Weight; mobile behavior change program for weight loss with 1:1 coaching, Noom Healthy Weight; mobile behavior change program for weight loss
Behavioral
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Conditions
Tuberous Sclerosis Complex Associated Neuropsychiatric Disease
Interventions
Cannabidiol Oral Solution [Epidiolex]
Drug
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
1 Year to 65 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
12
States / cities
Aurora, Colorado • New Haven, Connecticut • Gainesville, Florida + 9 more
Withdrawn Not applicable Interventional Accepts healthy volunteers

Dialectical Behavioral Therapy in Juvenile Justice

NCT05583279
Conditions
Non-Suicidal Self Injury, Suicide, Self-harm, Emotion Regulation
Interventions
Dialetical Behavioral Therapy for Adolescents
Behavioral
Lead sponsor
The Catholic University of America
Other
Eligibility
10 Years to 21 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Suicidal Ideation, Suicidal Behaviors
Interventions
Child - Safety Planning Intervention, C-SPI+ecological momentary assessment
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
6 Years to 12 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Negotiation Training for Family Caregivers of People With Alzheimer's Disease

NCT07859540
Conditions
Alzheimer's Disease (AD), Dementia, Cognitive Impairment
Interventions
NegotiAge, PlanYourLifespan
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
21 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Approaches for Improving Long-term Weight Loss

NCT03799289
Conditions
Obesity
Interventions
Behavioral weight loss followed by yoga instruction, Behavioral weight loss followed by cooking/dietary education instruction
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study: Stress Reduction in Caregivers of Children With ASD Using ACT

NCT05944289
Conditions
Caregiver Stress
Interventions
Acceptance and Commitment Therapy, Caregiver Support Group
Behavioral
Lead sponsor
Fielding Graduate University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Santa Barbara, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Problem Solving Intervention for Hospice Caregivers

NCT03712410
Conditions
Anxiety Generalized, Quality of Life, Depression
Interventions
PISCES
Behavioral
Lead sponsor
George Demiris, PhD
Other
Eligibility
18 Years and older
Enrollment
523 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Depression
Interventions
TEAM-Red, Waitlist
Behavioral · Other
Lead sponsor
Jennifer B. Levin
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Major Depression
Interventions
Family-based depression intervention, Usual care plus educational materials
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
50 Years and older · Male only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Stockton, California
Conditions
Fragile X Syndrome, Intellectual Disability
Interventions
Social gaze training
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
8 Years to 18 Years · Male only
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Stanford, California
Conditions
Obesity
Interventions
Morning exercise goal, Evening exercise goal, Time of choice exercise goal
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
35 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Covid19, Stress, Anxiety Depression
Interventions
Simha Kriya, Reading a Book
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
8,519 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Osteoarthritis, Knee, Obesity
Interventions
HFFS
Device
Lead sponsor
University of Southern Mississippi
Other
Eligibility
30 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Hattiesburg, Mississippi
Conditions
Mental Health Issue
Interventions
QActual
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina