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ClinicalTrials.gov public records Last synced Nov 6, 2026, 10:23 PM EST

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Showing 1–24 of 290 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Symptom Improvement. Clear all
Recruiting Not applicable Interventional

A Patient Activation Approach to Implementing Depression Treatment in Cardiac Patients

NCT07390331
View directory record Official record
Conditions
Depression and CVD
Interventions
iHeart Depcare tool
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Nov 6, 2026, 10:23 PM EST
Completed Phase 2Phase 3 Interventional

Effectiveness of a Telephone-Delivered Behavioral Treatment to Improve the Quality of Life of Older Adults With HIV

NCT00365690
View directory record Official record
Conditions
HIV Infections, Depression
Interventions
Telephone-administered coping improvement therapy, Telephone-administered supportive-expressive therapy, Individual therapy
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
50 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 22, 2022 · Synced Nov 6, 2026, 10:23 PM EST
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Local Participatory Systems Dynamics to Increase Reach of Evidence Based Addiction and Mental Health Care

NCT04356274
View directory record Official record
Conditions
PTSD, Depression, Alcohol Use Disorder, Opioid Use Disorder
Interventions
Participatory System Dynamics (PSD), Audit and Feedback (AF)
Other
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years and older
Enrollment
720 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Nov 6, 2026, 10:23 PM EST
Recruiting Phase 1 Interventional

Study of SFA002 in Patients with Mild to Moderate Psoriasis Plaques

NCT05642182
View directory record Official record
Conditions
Psoriasis
Interventions
SFA002
Drug
Lead sponsor
SFA Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
Pompano Beach, Florida • Fargo, North Dakota • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Nov 6, 2026, 10:23 PM EST
Active, not recruiting Not applicable Interventional

Pulmonary Arterial Hypertension Improvement With Nutrition and Exercise (PHINE)

NCT03288025
View directory record Official record
Conditions
Pulmonary Arterial Hypertension, Insulin Resistance
Interventions
Nutrition and Exercise
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Nov 6, 2026, 10:23 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Device for Improving Skin Quality and Texture on the Face and Neck

NCT06645366
View directory record Official record
Conditions
Wrinkle, Pigmentation, Skin Laxity, Skin Scarring
Interventions
Treatment with BTL-785F
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
22 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
Greenwood Village, Colorado • Chevy Chase, Maryland • Birmingham, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Nov 6, 2026, 10:23 PM EST
Completed Phase 3 Interventional

Walkbot Robotic Training for Improvement in Gait

NCT03554642
View directory record Official record
Conditions
Ischemic Stroke, Gait, Hemiplegic
Interventions
Walkbot, Physical Therapy
Device · Behavioral
Lead sponsor
Burke Medical Research Institute
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2020 · Synced Nov 6, 2026, 10:23 PM EST
Active, not recruiting Not applicable Interventional

Remote Game-based Exercise Program for Cognitive and Motor Function Improvement

NCT05235113
View directory record Official record
Conditions
Mild Cognitive Impairment, Dementia, Cognitive Impairment, Memory Loss
Interventions
Tele-Exergame Platform, No Tele-Exergame Platform
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
55 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Los Angeles, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Nov 6, 2026, 10:23 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Training Language and Literacy for Children Who Use CIs

NCT03582566
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
Phonological Awareness, Working Memory, Phonological Awareness + Working Memory, Active Control
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
5 Years to 7 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
2
States / cities
Tallahassee, Florida • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Nov 6, 2026, 10:23 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

A Prospective Trial of an Endoscopic Quality Improvement Project

NCT02325635
View directory record Official record
Conditions
Colon Polyps
Interventions
Educational Training
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 13, 2015 · Synced Nov 6, 2026, 10:23 PM EST
Completed Not applicable Interventional Results available

Design and Testing of a Web-Based Tool for the Improvement of End-of-Life Planning in Patients With Advanced Cancer

NCT05564468
View directory record Official record
Conditions
Hematopoietic and Lymphoid System Neoplasm, Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
Interventions
Best Practice, Internet-Based Intervention, Questionnaire Administration
Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Nov 6, 2026, 10:23 PM EST
Completed Not applicable Interventional Results available

Mandibular Advancement Device and Changes in Nocturia

NCT05562388
View directory record Official record
Conditions
Obstructive Sleep Apnea, Nocturia, OSA
Interventions
Somnodent Classic
Device
Lead sponsor
Isabel Moreno Hay
Other
Eligibility
18 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Nov 6, 2026, 10:23 PM EST
Withdrawn No phase listed Observational

Effects of Bariatric Surgery on Breast Density Improvement and Impact on Breast Cancer Risk in Severe Obese Patients

NCT04170335
View directory record Official record
Conditions
Breast Cancer, Morbid Obesity, Bariatric Surgery Candidate
Interventions
Bariatric surgery
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years to 74 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Nov 6, 2026, 10:23 PM EST
Not listed Not applicable Interventional

The Vitality Project for Fatigued Female Cancer Survivors

NCT03259438
View directory record Official record
Conditions
Fatigue, Cancer Survivorship
Interventions
Qigong, Healthy Living (CHIP + Pre-Train)
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Nov 6, 2026, 10:23 PM EST
Completed No phase listed Observational

Portable Oxygen Concentrator to Improve Quality of Life in Chronic Obstructive Pulmonary Disease

NCT01948544
View directory record Official record
Conditions
COPD
Interventions
Not listed
Lead sponsor
StratiHealth
Industry
Eligibility
65 Years to 85 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Oceanside, California • Vista, California • Westminster, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Nov 6, 2026, 10:23 PM EST
Completed Not applicable Interventional

A System for Preference Assessment in Mental Health

NCT02183844
View directory record Official record
Conditions
Mental Disorders, Schizophrenia, Overweight, Obesity
Interventions
Psychosocial Weight Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Nov 6, 2026, 10:23 PM EST
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Care.Coach Avatars for Improvement of Outcomes in Hospitalized Elders, Including Mitigation of Falls and Delirium: a Multi-Site Clinical Study

NCT03832192
View directory record Official record
Conditions
Delirium, Fall Injury
Interventions
care.coach Avatar (HELP-Protocolized)
Behavioral
Lead sponsor
Victor Wang
Industry
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Nov 6, 2026, 10:23 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Therapeutic Resources for Attention Improvement With Neuroimaging for TBI

NCT02082509
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
8 Years to 16 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2018 · Synced Nov 6, 2026, 10:23 PM EST
Completed Phase 1 Interventional Accepts healthy volunteers

Use of Interactive Gaming for Enhanced Function After Spinal Cord Injury

NCT01537978
View directory record Official record
Conditions
Paraplegia and Tetraplegia
Interventions
Video gaming for enhanced function after spinal cord injury.
Other
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Nov 6, 2026, 10:23 PM EST
Terminated Not applicable Interventional

Rhinogenic Headache Improvement After Nasal Operation

NCT00580307
View directory record Official record
Conditions
Headache
Interventions
Septoplasty, Septoplasty and endoscopic contact point correction
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Nov 6, 2026, 10:23 PM EST
Completed Not applicable Interventional

Impact of Lifestyle Changes on Telomeric Activity in Patients With Chronic Pain

NCT03056417
View directory record Official record
Conditions
Chronic Pain
Interventions
The Complete Health Improvement Program
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
40 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 30, 2020 · Synced Nov 6, 2026, 10:23 PM EST
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Acute Headache Treatment in Pregnancy: Occipital Nerve Block vs PO Acetaminophen With Caffeine

NCT03951649
View directory record Official record
Conditions
Headache, Pregnancy Related, Occipital Nerve Block
Interventions
Occipital Nerve Block
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
16 Years to 60 Years · Female only
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 20, 2023 · Synced Nov 6, 2026, 10:23 PM EST
Active, not recruiting Not applicable Interventional

Evaluating SUI-100™, A Non-Invasive Device for the Treatment of Stress Urinary Incontinence

NCT06862648
View directory record Official record
Conditions
Stress Urinary Incontinence (SUI)
Interventions
Acoustic Stimulation Therapy Device, Sham Acoustic Stimulation Therapy Device
Device
Lead sponsor
Acoustic Wave Cell Therapy, Inc.
Industry
Eligibility
22 Years to 77 Years · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
9
States / cities
Phoenix, Arizona • Lakeland, Florida • Boise, Idaho + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Nov 6, 2026, 10:23 PM EST
Recruiting Phase 1Phase 2 Interventional

High Dose Steroid Therapy (Prednisone or Methylprednisolone) for the Improvement of Symptoms of Late Radiation-Associated Lower Cranial Neuropathy in Oropharyngeal Cancer Survivors

NCT04151082
View directory record Official record
Conditions
Cranial Nerve Disorder, Head and Neck Carcinoma, Oropharyngeal Carcinoma
Interventions
Methylprednisolone, Prednisone, Quality-of-Life Assessment, Questionnaire Administration
Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Nov 6, 2026, 10:23 PM EST