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Showing 1–24 of 985 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Symptoms of Anxiety Clear all
Completed Not applicable Interventional Results available

Pain and Smoking Study

NCT02971137
View directory record Official record
Conditions
Smoking, Pain, Smoking Cessation
Interventions
Smoking Cessation plus CBI, Smoking Cessation Standard
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
371 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
West Haven, Connecticut • Leeds, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Utilization of Different Virtual Reality Experiences

NCT04828980
View directory record Official record
Conditions
Surgery, Pain, Postoperative, Anxiety, Otolaryngological Disease
Interventions
Oculus Quest: TRIPP, Oculus Quest: Angry Birds
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 89 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Vibrating Device Distraction on Mechanical Pain Thresholds Induced by Needle Sham

NCT06271642
View directory record Official record
Conditions
Pain, Anxiety
Interventions
Bluetooth Haptic Device (Experimental Frequency) + Needle Sham only, Bluetooth Haptic Device (Control Frequency) + Needle Sham only
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 99 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Walking Green: The Effects of Walking in Forested and Urban Areas

NCT03950661
View directory record Official record
Conditions
Mood, Stress, Anxiety, Depression, Obesity, Health Behavior, Physical Activity
Interventions
Walking
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 35 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Jul 22, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional

Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans

NCT06162741
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD), Depression, Anxiety
Interventions
Primary Care Brief Mindfulness Training (PCBMT), Moving Forward (MF)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Phoenix, Arizona • San Diego, California • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Developing Mental Health Supports for Autistic Students

NCT04926090
View directory record Official record
Conditions
Autism Spectrum Disorder, Depression, Anxiety
Interventions
Emotional Support Plan - Clinician Guided (ESP-C), Emotional Support Plan - Self Guided (ESP-S)
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
17 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Integrating Solution Focused Interventions in Integrated Care

NCT05838222
View directory record Official record
Conditions
Depression, Diabetes Mellitus, Hypertension, Anxiety Disorders
Interventions
Solution Focused Intervention, Treatment as Usual
Behavioral · Other
Lead sponsor
University of Georgia
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 17, 2023 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optimizing Mental Health in Orthopedic Care

NCT05194722
View directory record Official record
Conditions
Anxiety, Depression, Back Pain, Neck Pain
Interventions
Wysa mobile app
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jul 22, 2026, 5:57 PM EDT
Enrolling by invitation Not applicable Interventional

Psychobiological Interventions in Pregnancy

NCT06430853
View directory record Official record
Conditions
Pregnancy Complications, Mental Health Issue, Depression, Anxiety, Pregnancy, High Risk, Biological Clock Disturbance
Interventions
Step count goal, Actigraph watch
Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jul 22, 2026, 5:57 PM EDT
Completed No phase listed Observational

Patient-Reported Outcomes in Adults With Congenital Heart Disease

NCT02150603
View directory record Official record
Conditions
Heart Defects, Congenital
Interventions
Not listed
Lead sponsor
Philip Moons
Other
Eligibility
18 Years and older
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
6
States / cities
Stanford, California • St Louis, Missouri • Omaha, Nebraska + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2015 · Synced Jul 22, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Confirmatory Efficacy of the Building a Strong Identity and Coping Skills Program

NCT05789446
View directory record Official record
Conditions
Chronic Stress, Anxiety, Depression
Interventions
Building a Strong Identity and Coping Skills
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
11 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
5
States / cities
Harrisburg, Pennsylvania • Hershey, Pennsylvania • Spring Mills, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Phase 1 Interventional

Efficacy of Music Therapy Protocols for Burn Debridement

NCT00822497
View directory record Official record
Conditions
Pain Management
Interventions
Music-Based Imagery (MBI), Music Alternate Engagement (MAE)
Behavioral
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
7 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 22, 2010 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Music and Local Anesthesia During Dermatologic Procedures

NCT04317170
View directory record Official record
Conditions
Pain, Anxiety
Interventions
Music
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 22, 2020 · Synced Jul 22, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors

NCT04479696
View directory record Official record
Conditions
Glioblastoma, WHO Grade II Glioma, WHO Grade III Glioma
Interventions
Educational Intervention, Questionnaire Administration, Survey Administration, Video
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional

A Trial of a Positive Psychology Intervention for Older Adults (RESET)

NCT05451589
View directory record Official record
Conditions
Depressive Symptoms, Anxiety, Chronic Pain, Fatigue, Loneliness, Stress, Psychological
Interventions
RESET, Wellness Check Control
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
457 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jul 22, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional

Personalized Mobile Cognitive Behavioral Therapy Application

NCT05699525
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, Depression, Bipolar Disorder, Symptoms
Interventions
Personalized MAYA Mobile App, General MAYA Mobile App
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 25 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Health Benefits of Gardening

NCT03266120
View directory record Official record
Conditions
Anxiety, Depression, Healthy, Mood Disturbance, Stress, Quality of Life, Physical Activity, Social Interaction
Interventions
Art, Gardening
Other
Lead sponsor
University of Florida
Other
Eligibility
26 Years to 49 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 5, 2018 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional Results available

Presence of a Companion During Performance of Neuraxial Labor Analgesia

NCT02982213
View directory record Official record
Conditions
Anxiety, Pain, Health Knowledge, Attitudes, Practice
Interventions
Companion Present
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 11, 2021 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional

The Impact of Simulated Forest Immersion Therapy on Pain and Anxiety in Patients Axial Spondyloarthritis (axSpA)

NCT06072859
View directory record Official record
Conditions
Axial Spondyloarthritis
Interventions
Humidified Forest Oils, Forest oils and audio-visual forest exposure
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Widowed Elders Lifestyle After Loss

NCT02631291
View directory record Official record
Conditions
Mood Disorders, Depression, Anxiety, Grief, Bereavement, Health Behavior
Interventions
Behavioral self-monitoring, Behavioral self-monitoring + Motivational interviewing
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2020 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Integrating a Suite of Mental Health Apps for Depression in a Healthcare Setting

NCT05274620
View directory record Official record
Conditions
Depression, Anxiety
Interventions
IntelliCare
Behavioral
Lead sponsor
Adaptive Health, Inc
Industry
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • Florence, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Feasibility Trial of an Online Course (eMB) to Reduce Anxiety and Depression for Pregnant Women and Their Partners

NCT05867680
View directory record Official record
Conditions
Anxiety Disorders Generalized, Depression
Interventions
Online Mothers and Babies Course (eMB)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Jul 22, 2026, 5:57 PM EDT
Completed Phase 3 Interventional

Treatment of Panic Disorder: Long Term Strategies

NCT00000368
View directory record Official record
Conditions
Panic Disorder, Agoraphobia
Interventions
Cognitive behavior therapy, Paroxetine or other medication - algorithm used
Behavioral · Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years and older
Enrollment
379 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2004
U.S. locations
4
States / cities
New Haven, Connecticut • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2014 · Synced Jul 22, 2026, 5:57 PM EDT
Active, not recruiting Not applicable Interventional

Effects of Musical Intervention on Patient Pain and Anxiety for Office-based Procedures

NCT06235996
View directory record Official record
Conditions
Chronic Pain
Interventions
Office-based procedure indicated for chronic pain with music, Office-based procedure indicated for chronic pain without music
Procedure
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Wesley Chapel, Florida • Zephyrhills, Florida
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Jul 22, 2026, 5:57 PM EDT