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ClinicalTrials.gov public records Last synced Oct 18, 2026, 2:48 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 1,005 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Symptoms of Anxiety Clear all
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes

NCT04743466
View directory record Official record
Conditions
Anxiety Disorder, Depression, Genetic Disorder, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Interventions
Electronic Health Record Review
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Possible Therapy by Phone for Caregivers

NCT04634396
View directory record Official record
Conditions
Anxiety, Anxiety Disorders and Symptoms, Caregiver Burnout
Interventions
ACT Acceptance and Commitment Therapy
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 29, 2023 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Results available

Stepped-Care Telehealth for Distress in Cancer Survivors

NCT03060096
View directory record Official record
Conditions
Anxiety, Depressive Symptoms, Sleep Disturbance, Recurrent Disease, Fatigue, Quality of Life, Cancer
Interventions
Severe Anxiety/depression: High Intensity Stepped Care, Moderate Anxiety/depression: Low Intensity Stepped care, Enhanced Usual Care Control
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
166
States / cities
Fort Smith, Arkansas • Fresno, California • Modesto, California + 129 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 18, 2026, 2:48 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Mindfulness on Pain After Total Knee Arthroplasty

NCT06118073
View directory record Official record
Conditions
Total Knee Replacement, Post Operative Pain, Opioid Use
Interventions
Headspace, Total Knee Replacement
Other · Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With Dementia

NCT04338750
View directory record Official record
Conditions
Anxiety, Anxiety Generalized, Anxiety Disorders and Symptoms, Caregiver Burnout
Interventions
Telephone Acceptance and Commitment Therapy Intervention for Caregivers, minimally-Enhanced Usual Care
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating a Digital Peer Mentoring Platform With College Student Populations

NCT05764785
View directory record Official record
Conditions
Well-Being, Psychological, Anxiety, Depression, Mentoring to Support the Transition to College
Interventions
MentorPRO
Behavioral
Lead sponsor
Academic Web Pages
Industry
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Oct 18, 2026, 2:48 AM EDT
Completed No phase listed Observational

Evaluation of the Genetics of Bipolar Disorder

NCT00001174
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 100 Years
Enrollment
4,210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1994
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 18, 2026, 2:48 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Network Study: Soldiers Connecting for Work and Health

NCT04463225
View directory record Official record
Conditions
Alcohol Use Disorder, Depression
Interventions
Internet-Delivered Brief Intervention
Other
Lead sponsor
Cornell University
Other
Eligibility
18 Years to 62 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated May 26, 2023 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Drumming Groups for Parents of Autistic Children

NCT07375043
View directory record Official record
Conditions
Anxiety Acute, Stress, Depression and Quality of Life, Stress in Parents of Autistic Children
Interventions
Group Drumming
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Randomized Clinical Trial of a Multi-Modal Palliative Care Intervention

NCT04773639
View directory record Official record
Conditions
Depression, Anxiety, Metastatic Cancer
Interventions
Multi-Modal Palliative Care Intervention, Usual Care Control Condition
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Results available

Evaluation of a Crowd-Powered Web Platform for Depression and Anxiety

NCT04226742
View directory record Official record
Conditions
Depression, Anxiety
Interventions
ADAPT Platform (Treatment), ADAPT Comparison (Control)
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2023 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Integrating Solution Focused Interventions in Integrated Care

NCT05838222
View directory record Official record
Conditions
Depression, Diabetes Mellitus, Hypertension, Anxiety Disorders
Interventions
Solution Focused Intervention, Treatment as Usual
Behavioral · Other
Lead sponsor
University of Georgia
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Skin Picking Approach Avoidance Task

NCT04099537
View directory record Official record
Conditions
Skin-Picking
Interventions
Computerized cognitive training
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 28, 2022 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RCT of Automated Conversational Agent vs. Treatment as Usual for the Management of Perinatal Mood

NCT03646539
View directory record Official record
Conditions
Cognitive Therapy, Depression, Postpartum, Mental Health, Depression, Depressive Disorder, Anxiety, Telemedicine
Interventions
Use of smartphone application (app), Treatment as usual
Behavioral · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Oct 18, 2026, 2:48 AM EDT
Recruiting Not applicable Interventional

Fear of Recurrence and Stopping Immunotherapy

NCT04761328
View directory record Official record
Conditions
Cognitive Behavioral Therapy
Interventions
cognitive behavioral therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Psychological Intervention For Brain Tumor Caregivers

NCT04109209
View directory record Official record
Conditions
Malignant Glioma, Anxiety, Caregiver Burden, Malignant Brain Tumor
Interventions
Psychosocial Intervention Group, Usual Care Group
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Impact of Pre-Sedation Virtual Reality Game on Post-Discharge Negative Behaviors in the Pediatric Emergency Department

NCT03980067
View directory record Official record
Conditions
Behavior, Child, Anxiety
Interventions
Virtual Reality Game
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
6 Years to 17 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Effectiveness of a Unified Transdiagnostic Treatment in Routine Care

NCT02944994
View directory record Official record
Conditions
Anxiety, Traumatic Stress Disorders, Depression
Interventions
Unified protocol, Routine Care
Other
Lead sponsor
Boston University
Other
Eligibility
18 Years to 100 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Results available

Community Study of Outcome Monitoring for Emotional Disorders in Teens

NCT02567266
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Unified Protocol for Adolescents (UP-A), Youth Outcomes Questionnaire, Treatment as Usual
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 18 Years
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
West Hartford, Connecticut • Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Aug 18, 2021 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Ketamine for Depression: An MRI Study

NCT02544607
View directory record Official record
Conditions
Depression, Anxious Depression, Major Depressive Disorder
Interventions
Ketamine, Magnetic Resonance Imaging (MRI)
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional

LoveYourBrain Yoga for Multiple Sclerosis

NCT03827928
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Yoga/meditation
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional

The Effects of Probiotic Supplementation on State and Trait Stress, Anxiety, and Depression Symptoms in Stressed Adults

NCT07216729
View directory record Official record
Conditions
Anxiety Symptoms, Perceived Stress, Depressive Symptoms
Interventions
Lactobacillus reuteri DSM 17938, Placebo
Dietary Supplement · Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 45 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Web-based Management of Pediatric Functional Abdominal Pain

NCT02327377
View directory record Official record
Conditions
Gastrointestinal Disorders, Functional
Interventions
Online Cognitive Behavior Therapy, Online Education
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
11 Years to 17 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 28, 2019 · Synced Oct 18, 2026, 2:48 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Neural Mechanisms of Clinically Designed Improvisatory Music for Alzheimer's Disease

NCT05477862
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Clinically Designed Improvisatory Music
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
55 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 18, 2026, 2:48 AM EDT