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ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:43 PM EDT

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Showing 385–408 of 600 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Symptoms of Depression and Anxiety Clear all
Recruiting No phase listed Observational

Evaluation of the PACE/PACENET BHL Clinical Program

NCT02463266
View directory record Official record
Conditions
Depression, Anxiety, Pain, Chronic
Interventions
SUSTAIN Monitoring and Care Management
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
65 Years and older
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 23, 2026, 1:43 PM EDT
Completed Phase 2 Interventional Results available

Hormonal Factors in the Treatment of Anorexia Nervosa

NCT01121211
View directory record Official record
Conditions
Anorexia Nervosa, Eating Disorder, Anxiety, Depression
Interventions
Testosterone, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 23, 2026, 1:43 PM EDT
Completed Not applicable Interventional

Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life Outcomes

NCT03925168
View directory record Official record
Conditions
End Stage Renal Disease, Depression, Anxiety, Major Depressive Disorder, Generalized Anxiety Disorder, Compliance, Patient, Compliance, Medication, Mood, Pain, Energy Supply; Deficiency, Quality of Life, Blood Pressure, Heart Rate Fast
Interventions
Music therapy
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
New Orleans, Louisiana • Terrytown, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Oct 23, 2026, 1:43 PM EDT
Completed Not applicable Interventional

Affect Treatment for Depression and Anxiety

NCT05203861
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Positive Affect Treatment, Negative Affect Treatment
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Los Angeles, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2025 · Synced Oct 23, 2026, 1:43 PM EDT
Withdrawn No phase listed Observational

A Prospective Study of Body Image, Social Avoidance and Distress and Psychological Functioning in Burn Patients

NCT01136070
View directory record Official record
Conditions
Depression, Anxiety, Body Image
Interventions
Not listed
Lead sponsor
Saint Elizabeth Regional Medical Center
Other
Eligibility
19 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 13, 2016 · Synced Oct 23, 2026, 1:43 PM EDT
Completed Not applicable Interventional

Self-Management Program for Persons With Limb Loss

NCT00198692
View directory record Official record
Conditions
Amputation, Depression, Pain, Anxiety
Interventions
self-management
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 28, 2008 · Synced Oct 23, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Patient and Family Centered Care in Advanced Critical Illness

NCT01844492
View directory record Official record
Conditions
Anxiety, Depression
Interventions
The PARTNER Intervention, ICU Usual Care Control
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced Oct 23, 2026, 1:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing Adapted Self-Help Plus (SH+) for Stress and Well-Being in International Students at a U.S. University

NCT07188467
View directory record Official record
Conditions
Stress, Psychological, Depression and/or Anxiety in the Mild-to-moderate Range, Loneliness, Adjustment, Psychological
Interventions
Digitized SH+
Behavioral
Lead sponsor
The New School
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 23, 2026, 1:43 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Radical Openness for Adolescents Pilot

NCT05913557
View directory record Official record
Conditions
Anorexia Nervosa, Obsessive-Compulsive Disorder, Social Phobia, Depression, Anxiety
Interventions
Radically Open Dialectical Behavior Therapy (RO DBT)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
13 Years to 21 Years · Female only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 23, 2026, 1:43 PM EDT
Active, not recruiting Not applicable Interventional

The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity

NCT04953806
View directory record Official record
Conditions
COPD, Depression, Anxiety
Interventions
Step-CBT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 23, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating a Digital Peer Mentoring Platform With College Student Populations

NCT05764785
View directory record Official record
Conditions
Well-Being, Psychological, Anxiety, Depression, Mentoring to Support the Transition to College
Interventions
MentorPRO
Behavioral
Lead sponsor
Academic Web Pages
Industry
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Oct 23, 2026, 1:43 PM EDT
Completed No phase listed Observational

Epigenetics and Psychoneurologic Symptoms in Women With Breast Cancer

NCT01411943
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years to 81 Years · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Newport News, Virginia • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 8, 2015 · Synced Oct 23, 2026, 1:43 PM EDT
Recruiting Not applicable Interventional

My Wellbeing Guide: A Novel Tool for Managing Stress and Improving Quality of Life

NCT05369429
View directory record Official record
Conditions
Cancer, Anxiety, Depressive Symptoms
Interventions
My Wellbeing Guide
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
6,516 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 23, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness, Yoga, and Cardiovascular Disease

NCT00696852
View directory record Official record
Conditions
Cardiovascular Disease, Stress, Anxiety, Depression
Interventions
Mindfulness Meditation, Yoga, Exercise, Relaxation, and Health Education
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years to 75 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2012 · Synced Oct 23, 2026, 1:43 PM EDT
Active, not recruiting Not applicable Interventional

Virtual Reality Intervention for Patients Undergoing BMT

NCT05629676
View directory record Official record
Conditions
Bone Marrow Transplant Complications
Interventions
BMT-VR
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 23, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of a Yoga- and Mindfulness-Based Intervention for Resident Physicians

NCT03687450
View directory record Official record
Conditions
Burnout, Professional, Anxiety, Depression, Stress
Interventions
RISE yoga-based program
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 23, 2020 · Synced Oct 23, 2026, 1:43 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Cardiovascular Biomarkers and Quetiapine in Depression and Anxiety Patients

NCT00951483
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Quetiapine-XR
Drug
Lead sponsor
Loyola University
Other
Eligibility
20 Years to 65 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 24, 2016 · Synced Oct 23, 2026, 1:43 PM EDT
Recruiting Phase 2Phase 3 Interventional

Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)

NCT06273527
View directory record Official record
Conditions
Anxiety Disorders, Depression, Post Traumatic Stress Disorder
Interventions
COGENT, Sham Program
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 55 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Oct 23, 2026, 1:43 PM EDT
Completed Not applicable Interventional

Impact of Massage Therapy and Music Therapy on the Quality of Life of Hospice Patients

NCT03217682
View directory record Official record
Conditions
Pain, Anxiety, Depression, Quality of Life
Interventions
Music Therapy, Massage Therapy
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Oct 23, 2026, 1:43 PM EDT
Terminated Phase 2 Interventional Results available

Buspirone Therapy for Localized Epilepsy

NCT01496612
View directory record Official record
Conditions
Anxiety Disorder, Seizures, Epilepsy, Partial Epilepsy, Depression
Interventions
Buspirone, Placebo
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Oct 23, 2026, 1:43 PM EDT
Not listed No phase listed Observational

CAMPUS Expanded "Classification and Assessment of Mental Health Performance Using Semantics Expanded"

NCT04493736
View directory record Official record
Conditions
Suicide, Suicidal, Suicide, Attempted, Suicidal Ideation, Depression, Anxiety, Aggression, Trauma, Psychological
Interventions
MHSAFE app recording
Behavioral
Lead sponsor
Clarigent Health
Industry
Eligibility
8 Years to 75 Years
Enrollment
2,000 participants
Timeline
2020 – 2024
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Oct 23, 2026, 1:43 PM EDT
Terminated Not applicable Interventional Results available

Feasibility - Beta Adrenergic Blockade (BB) in Cervical Cancer (CX)

NCT01902966
View directory record Official record
Conditions
Cervical Cancer
Interventions
Propranolol, Diary, Relaxation Audio Recording, Questionnaires
Drug · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Oct 23, 2026, 1:43 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Investigation of Neuro-hormonal Mechanisms of Hunger, Fullness and Obesity.

NCT01008371
View directory record Official record
Conditions
Obesity, Gastric Emptying, Anxiety, Depression, Panic Disorder
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2013 · Synced Oct 23, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Community Resilience Learning Collaborative and Research Network

NCT03977844
View directory record Official record
Conditions
Depression, Social Stress, Anxiety, Quality of Life, Disaster
Interventions
Technical Assistance, Community Engagement and Planning, Community Resources (CR), Community Resources + eBT
Other
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
258 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated May 24, 2021 · Synced Oct 23, 2026, 1:43 PM EDT