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ClinicalTrials.gov public records Last synced Oct 24, 2026, 2:48 AM EDT

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Showing 433–456 of 600 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Symptoms of Depression and Anxiety Clear all
Completed Not applicable Interventional Results available

Self-Defense Training in Women With Trauma

NCT01380379
View directory record Official record
Conditions
Depression, Anxiety, Stress Disorders, Post-Traumatic
Interventions
Life skills and self-defense training
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 24, 2026, 2:48 AM EDT
Completed Not applicable Interventional Results available

Behavioral Activation and Medication Optimization for Perioperative Mental Health Feasibility Study

NCT05110690
View directory record Official record
Conditions
Older Adults, Anxiety, Depression, Cardiac Surgery, Orthopedic Surgery, Major Surgical Resection of a Thoracic Malignancy, Major Surgical Resection of an Abdominal Malignancy
Interventions
Behavioral Activation, Medication Optimization
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Oct 24, 2026, 2:48 AM EDT
Completed Phase 2 Interventional

Symptom-specific TMS Targets for Depression and Anxiety

NCT04604210
View directory record Official record
Conditions
Depression, Anxiety, Major Depressive Disorder
Interventions
Transcranial magnetic stimulation
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Oct 24, 2026, 2:48 AM EDT
Completed Not applicable Interventional

The Treatment of Depression With Yoga and Walking

NCT02907476
View directory record Official record
Conditions
Depression, Major Depressive Disorder, PTSD, Anxiety
Interventions
Iyengar Yoga, Walking
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Oct 24, 2026, 2:48 AM EDT
Recruiting Phase 3 Interventional

Nebulized Ketamine for the Treatment of Major Depressive Disorder

NCT06752759
View directory record Official record
Conditions
Severe Depression, Moderate Depression, Ketamine, Midazolam, Peripheral Nervous System Agents, Central Nervous System Agents, Neurotransmitter Agents, Physiologic Effects of Drugs, Sensory System Agents, Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-Steroidal, Depressive Symptom, Hypnotics and Sedatives, Anti-anxiety Agents, Tranquilizing Agents, Psychotropic Drugs, Anesthetics Agent
Interventions
nebulized ketamine, nebulized midazolam
Drug
Lead sponsor
Theresa Jacob, PhD, MPH
Other
Eligibility
18 Years to 88 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 24, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Multimodal Investigation of Post COVID-19 in Females

NCT05225220
View directory record Official record
Conditions
Post COVID-19, Cognitive Dysfunction
Interventions
Parasym Device (of Parasym Ltd, UK) using Transcutaneous Vagus Nerve Stimulation (t-VNS)
Device
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2023 · Synced Oct 24, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Walking Green: The Effects of Walking in Forested and Urban Areas

NCT03950661
View directory record Official record
Conditions
Mood, Stress, Anxiety, Depression, Obesity, Health Behavior, Physical Activity
Interventions
Walking
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 35 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Oct 24, 2026, 2:48 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Evaluating the Effects of a Fermented Diet on Microbiome Diversity in Individuals With Long COVID

NCT06560554
View directory record Official record
Conditions
Long COVID
Interventions
Fermented foods, Control
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 24, 2026, 2:48 AM EDT
Not listed Not applicable Interventional

The Use of Transcranial Focused Ultrasound for the Treatment of Depression and Anxiety

NCT04250441
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Focused Transcranial Ultrasound
Device
Lead sponsor
Neurological Associates of West Los Angeles
Other
Eligibility
18 Years to 93 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2023 · Synced Oct 24, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial of Two On-Line Interventions for Child Brain Injury

NCT00178022
View directory record Official record
Conditions
Traumatic Brain Injury, Depression, Anxiety Disorders
Interventions
Case management and problem solving therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
5 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2008 · Synced Oct 24, 2026, 2:48 AM EDT
Suspended No phase listed Observational

An Examination of the Performance of QbMobile in Differential Diagnosis Associated With ADHD Symptoms

NCT07329673
View directory record Official record
Conditions
Bi-Polar Disorder, Autism Spectrum Disorder (ASD), Major Depression Disorders, Separation Anxiety Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder (GAD)
Interventions
Digital software application for cognitive performance and activity measurement (QbMobile, investigational device)
Device
Lead sponsor
Qbtech AB
Industry
Eligibility
6 Years to 60 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 24, 2026, 2:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Confirmatory Efficacy of the Building a Strong Identity and Coping Skills Program

NCT05789446
View directory record Official record
Conditions
Chronic Stress, Anxiety, Depression
Interventions
Building a Strong Identity and Coping Skills
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
11 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
5
States / cities
Harrisburg, Pennsylvania • Hershey, Pennsylvania • Spring Mills, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 24, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Activity Changes in Irritable Bowel Syndrome (IBS), Anxiety, and Depression Following the Use of Viome Precision Nutrition Program (VPNP)

NCT04905524
View directory record Official record
Conditions
Depression, Anxiety, IBS - Irritable Bowel Syndrome
Interventions
VIOME Precision Nutrition Program
Dietary Supplement
Lead sponsor
Viome
Industry
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Bothell, Washington
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Oct 24, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Health and Energy Through Active Living Every Day After Cancer Intervention for Cancer Survivors

NCT05356988
View directory record Official record
Conditions
Quality of Life, Cognitive Decline, Fatigue, Sleep, Anxiety, Depression
Interventions
Physical activity experiment, Balance and flexibility control
Behavioral
Lead sponsor
American Cancer Society, Inc.
Other
Eligibility
55 Years to 77 Years
Enrollment
415 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Kennesaw, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Oct 24, 2026, 2:48 AM EDT
Withdrawn Not applicable Interventional

Bridging the Gap to Improve Mental Health Treatment Utilization

NCT04558489
View directory record Official record
Conditions
Depression, Anxiety, Adolescent Behavior, Suicidal Ideation
Interventions
IPR + GMI
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
10 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Kittanning, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Oct 24, 2026, 2:48 AM EDT
Not listed Phase 3 Interventional

A Head-to-head Comparison of Virtual Reality Treatment for Post Traumatic Stress Disorder

NCT00978484
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Virtual Reality Exposure Therapy - Dynamic, Augmented Exposure Therapy
Behavioral
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
Camp Pendlton, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2014 · Synced Oct 24, 2026, 2:48 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Whole Selves User Testing and Feasibility Study

NCT06392542
View directory record Official record
Conditions
Alcohol Use, Unspecified, Relationship, Social, Depression, Anxiety
Interventions
Whole Selves
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 30 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 24, 2026, 2:48 AM EDT
Recruiting Phase 2 Interventional

A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety

NCT06820723
View directory record Official record
Conditions
Depression, Anxiety, Major Depressive Disorder
Interventions
CYB003, Placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 24, 2026, 2:48 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating the Effects of Stress in Pregnancy

NCT00525226
View directory record Official record
Conditions
Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, Obsessive Compulsive Disorder (OCD)
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,431 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 20, 2013 · Synced Oct 24, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Kind Minds Program for Youth With Anxiety and Depression

NCT05353751
View directory record Official record
Conditions
Child Anxiety, Depression
Interventions
Kind Minds Program
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 17 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Imperial, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 24, 2026, 2:48 AM EDT
Completed Phase 2 Interventional

New Drugs in the Treatment of Mood Disorders

NCT00001482
View directory record Official record
Conditions
Anxiety Disorder, Mood Disorder, Psychotic Disorder
Interventions
Lamotrigine (Lamictal® (Registered Trademark), Gabapentin (Neurontin® (Registered Trademark))
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 24, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Reducing Isolation and Feeling of Loneliness During Critical Illness

NCT05537311
View directory record Official record
Conditions
Critical Illness, Social Isolation, Anxiety, Depression, Post Intensive Care Unit Syndrome
Interventions
Social Engagement
Behavioral
Lead sponsor
Kirby Mayer
Other
Eligibility
18 Years to 99 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 14, 2023 · Synced Oct 24, 2026, 2:48 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes

NCT04743466
View directory record Official record
Conditions
Anxiety Disorder, Depression, Genetic Disorder, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Interventions
Electronic Health Record Review
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Oct 24, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Student Outcomes of Integrative Mental Health Services

NCT02877875
View directory record Official record
Conditions
Anxiety, Depression, Trauma, Behavior Problems
Interventions
Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems, Monitoring and Feedback System, Treatment as usual
Behavioral · Other
Lead sponsor
Harvard University
Other
Eligibility
7 Years to 14 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 24, 2026, 2:48 AM EDT