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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:06 PM EDT

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Showing 169–192 of 600 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Symptoms of Depression and Anxiety Clear all
Completed Not applicable Interventional

Clinical Study Evaluating Effects of Pharmacogenetic-guided vs Standard-of-Care Treatment on Depression and/or Anxiety

NCT02878928
View directory record Official record
Conditions
Depression, Anxiety
Interventions
IDgenetix Neuropsychiatric Test Panel
Genetic
Lead sponsor
AltheaDx
Industry
Eligibility
18 Years and older
Enrollment
579 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
17
States / cities
Rolling Hills, California • San Diego, California • Torrance, California + 13 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2016 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa

NCT02615119
View directory record Official record
Conditions
Anorexia Nervosa, Major Depressive Disorder, Generalized Anxiety Disorder, Panic Disorder, Brain Injury
Interventions
Isoproterenol, Normal saline
Drug
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional Results available

Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts

NCT04225624
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
Emotion Regulation Therapy - Attention Regulation (AR-ERT), Supportive Psychotherapy (SPT)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional

Feasibility Trial of an Online Course (eMB) to Reduce Anxiety and Depression for Pregnant Women and Their Partners

NCT05867680
View directory record Official record
Conditions
Anxiety Disorders Generalized, Depression
Interventions
Online Mothers and Babies Course (eMB)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Oct 21, 2026, 4:06 PM EDT
Active, not recruiting Not applicable Interventional

Neurotechnology Following Traumatic Brain Injury

NCT03649958
View directory record Official record
Conditions
Post-Concussion Symptoms, Insomnia, Pain, Chronic, Depressive Symptoms
Interventions
HIRREM-SOP or Cereset, Cereset 2x
Device
Lead sponsor
Brain State Technologies, LLC
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional

Testing the Right Question Project (RQP) Health Education Strategy in a Mental Health Setting

NCT00134615
View directory record Official record
Conditions
Diagnosis, Psychiatric
Interventions
RQP patient health education module
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
2
States / cities
Cambridge, Massachusetts • Chelsea, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2016 · Synced Oct 21, 2026, 4:06 PM EDT
Terminated Not applicable Interventional

Cognitive-Behavioral Stress Management Device for the Treatment of Anxiety and Depressive Symptoms in Patients With Stage I-III Breast or Lung Cancer

NCT04705025
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8, Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8, Stage IA2 Lung Cancer AJCC v8, Stage IA3 Lung Cancer AJCC v8, Stage IB Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8
Interventions
Cognitive Behavior Therapy, Interview, Quality-of-Life Assessment, Questionnaire Administration
Behavioral · Other
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 25, 2023 · Synced Oct 21, 2026, 4:06 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional Results available

The Effects of Ginseng on Cancer-Related Fatigue

NCT01375114
View directory record Official record
Conditions
Advanced Cancers, Solid Tumors
Interventions
Panax Ginseng, Placebo, Questionnaires
Drug · Dietary Supplement · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 21, 2026, 4:06 PM EDT
Recruiting Phase 1Phase 2 Interventional

Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

NCT05685368
View directory record Official record
Conditions
Race-related Stress, Depression, Anxiety, Quality of Life, Stress Reaction
Interventions
ACT for SCD
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
14 Years to 21 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional Results available

Brain Stimulation and Enhancing Cognition in Older Adults

NCT03653351
View directory record Official record
Conditions
Cognitive Impairment, Mild, Depressive Symptoms, Anxiety
Interventions
Active Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Oct 21, 2026, 4:06 PM EDT
Not yet recruiting Not applicable Interventional

The Effect of the Safe and Sound Protocol on Depression and Anxiety Symptoms

NCT06701578
View directory record Official record
Conditions
Anxiety, Depression
Interventions
Safe and Sound Protocol, Control
Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness, Yoga, and Cardiovascular Disease

NCT00696852
View directory record Official record
Conditions
Cardiovascular Disease, Stress, Anxiety, Depression
Interventions
Mindfulness Meditation, Yoga, Exercise, Relaxation, and Health Education
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years to 75 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2012 · Synced Oct 21, 2026, 4:06 PM EDT
Terminated Not applicable Interventional

Mobile Cognitive Behavioral Therapy for Medical and Graduate Students

NCT05823922
View directory record Official record
Conditions
Anxiety Disorders, Depression
Interventions
Clinician Delivered CBT, Supplemental MAYA App
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 40 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Challenge! Adolescent Obesity Prevention

NCT03103269
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Challenge! Small Group Intervention, Challenge! Environmental Intervention
Behavioral · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
10 Years and older
Enrollment
789 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 16, 2019 · Synced Oct 21, 2026, 4:06 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Two Sessions of Coach-Delivered Core Transformation for Distress and Well-Being

NCT07879196
View directory record Official record
Conditions
Psychological Distress, Psychological Well-being
Interventions
Core Transformation Process
Behavioral
Lead sponsor
Andreas NLP (Legal Entity - Real People Press)
Other
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 21, 2026, 4:06 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Addressing Mental Health of Cancer Patients and Caregivers Using a Mobile App Suite

NCT03488745
View directory record Official record
Conditions
Mental Health Wellness 1, Depression, Anxiety
Interventions
IntelliCare + Phone Coaching
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional Results available

The PRISM Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults With Advanced Cancer

NCT03668223
View directory record Official record
Conditions
Cancer, Quality of Life, Anxiety, Depression, Hope, Coping Skills, Communication
Interventions
Promoting Resilience in Stress Management (PRISM)
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
12 Years to 24 Years
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
5
States / cities
Los Angeles, California • Boston, Massachusetts • Pittsburgh, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional

Effect of Whole Blueberry Powder Consumption on Depression in a Central Louisiana Population

NCT04398784
View directory record Official record
Conditions
Depression, Depression, Anxiety, Inflammation
Interventions
Freeze Dried Blueberry Powder - 71717, USHBC Blueberry Placebo Formula #114
Dietary Supplement
Lead sponsor
Louisiana State University, Baton Rouge
Other
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Cottonport, Louisiana • Marksville, Louisiana
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sensation Awareness Focused Training for Spouses

NCT03129204
View directory record Official record
Conditions
Post Intensive Care Syndrome, Anxiety, Depression, Posttraumatic Stress Disorder, Sleep Deprivation
Interventions
SAF-T
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Oct 21, 2026, 4:06 PM EDT
Recruiting Not applicable Interventional

Telehealth Collaborative Care Model (CoCM) in Lung Cancer

NCT07102147
View directory record Official record
Conditions
Lung Cancer (Diagnosis), Anxiety, Depression in Adults
Interventions
High Touch Outreach
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional

Integrative Coping Group for Children

NCT01813669
View directory record Official record
Conditions
Childhood Depression, Childhood Anxiety, Pediatric Pain, Migraines, ADHD, Pediatric Stomach Pain, Musculoskeletal Pain
Interventions
Integrative Coping Group
Behavioral
Lead sponsor
Duke University
Other
Eligibility
10 Years to 12 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2014 · Synced Oct 21, 2026, 4:06 PM EDT
Not yet recruiting Not applicable Interventional

A Pre-post Pilot of a Smartphone Intervention

NCT07665346
View directory record Official record
Conditions
Mental Health Issue, Breast Cancer
Interventions
Digital Micro-Interventions
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 21, 2026, 4:06 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Whole Selves User Testing and Feasibility Study

NCT06392542
View directory record Official record
Conditions
Alcohol Use, Unspecified, Relationship, Social, Depression, Anxiety
Interventions
Whole Selves
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 30 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional

An Attachment Based Approach for Anxiety and Depression

NCT04719780
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Emotionally Focused Therapy for Individuals, Self-Help CBT Training
Behavioral
Lead sponsor
Saint Paul University
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 9, 2024 · Synced Oct 21, 2026, 4:06 PM EDT