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ClinicalTrials.gov public records Last synced Sep 26, 2026, 4:49 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Syndrome, Obstructive Sleep Apnea Clear all
Completed Not applicable Interventional Results available

Upper Airway Physical Therapy for the Treatment of Obstructive Sleep Apnea

NCT02109731
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
Negative airway pressure delivery
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Sep 26, 2026, 4:49 PM EDT
Not listed Not applicable Interventional

Peer-Driven Intervention for Sleep Apnea

NCT02056002
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Usual Care, Peer-Buddy System
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 85 Years
Enrollment
362 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 4, 2017 · Synced Sep 26, 2026, 4:49 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Safety and Tolerability of Gefapixant (MK-7264) in Participants With Obstructive Sleep Apnea (MK-7264-039)

NCT03882801
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Gefapixant, Placebo
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
4
States / cities
Hallandale, Florida • Hollywood, Florida • Atlanta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2024 · Synced Sep 26, 2026, 4:49 PM EDT
Completed Not applicable Interventional Results available

Efficacy of the OrthoApnea NOA® Mandibular Advancement Device in the Management of Obstructive Sleep Apnea.

NCT05139303
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Orthoapnea NOA®
Device
Lead sponsor
Isabel Moreno Hay
Other
Eligibility
18 Years to 79 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 26, 2026, 4:49 PM EDT
Active, not recruiting Phase 2 Interventional

Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome

NCT05933603
View directory record Official record
Conditions
Obstructive Sleep Apnea, Down Syndrome
Interventions
Atomoxetine and Oxybutynin (ato-oxy)
Drug
Lead sponsor
University of Arizona
Other
Eligibility
6 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 26, 2026, 4:49 PM EDT
Completed Not applicable Interventional

Dental Device for Treatment of Sleep Apnea

NCT01005940
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
Mandibular advancement device
Device
Lead sponsor
Ulysses Magalang MD
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Sep 26, 2026, 4:49 PM EDT
Recruiting Not applicable Interventional

Combination Tonsillectomy and Hypoglossal Nerve Stimulation for OSA Patients With Lateral Pharyngeal Collapse

NCT07724938
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep Disordered Breathing
Interventions
Tonsillectomy, HGNS
Procedure · Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 26, 2026, 4:49 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable

NCT06763549
View directory record Official record
Conditions
Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure, HFrEF - Heart Failure with Reduced Ejection Fraction, HFpEF - Heart Failure with Preserved Ejection Fraction, Syncopation, Syncope, Ischemic Cardiovascular Disease, STEMI, STEMI (ST Elevation MI), Atrial Fibrillation (AF), Atrial Enlargement, LVF, Conduction Defect, Conduction Abnormalities, Heart Block, Valvular Diseases, Cardiac Output, Low, Stroke Volume, Stroke Volume Variation, Hyperkalemia, Hypercalcemia, Hypocalcemia, LV Dysfunction, QT Prolongation, Sudden Cardiac Death Due to Cardiac Arrhythmia, Ventricular Arrhythmia, Pacing, Pacing Induced Dyssynchrony, Silent Ischemia, Pericarditis, Sleep Related Breathing Disorder, RSA, Apnea, Obstructive, Cardiac Output Measurement, Respiratory Impedance, CRT And/or ICD, Infarction, Cardiomyopathies, Primary, Hypertrophy
Interventions
SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C, SUBPROTOCOL D, SUBPROTOCOL E, SUBPROTOCOL F, SUBPROTOCOL G, SUBPROTOCOL H
Device
Lead sponsor
Peerbridge Health, Inc
Industry
Eligibility
18 Years and older
Enrollment
15,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 26, 2026, 4:49 PM EDT
Withdrawn Not applicable Interventional

Ultrasound Against Obstructive Sleep Apnea

NCT02788149
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Ultrasound Exam, Polysomnography
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 4, 2023 · Synced Sep 26, 2026, 4:49 PM EDT
Enrolling by invitation No phase listed Observational

Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index

NCT03062748
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 26, 2026, 4:49 PM EDT
Recruiting Not applicable Interventional

Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation

NCT07220525
View directory record Official record
Conditions
Obstructive Sleep Apnea, Premature Ventricular Contraction (PVC), Atrial Fibrillation (AF), Premature Atrial Contraction
Interventions
HGNS Use Randomized Instructions
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 26, 2026, 4:49 PM EDT
Completed Phase 1 Interventional

New Pharmacological Treatment for Obstructive Sleep Apnea

NCT00108498
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
mirtazapine
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
20 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Sep 26, 2026, 4:49 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Adherence to Health Coaching with Wearable Devices: Enhancing Patient Engagement and Outcomes

NCT06525337
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
STANDARDCARE (STAND) group, CONTROL (CON) group
Behavioral · Other
Lead sponsor
Coastal Carolina University
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Conway, South Carolina • Cordova, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 8, 2024 · Synced Sep 26, 2026, 4:49 PM EDT
Recruiting Phase 1Phase 2 Interventional

Intermittent Hypoxia-initiated Plasticity in Humans: A Multi-pronged Therapeutic Approach to Treat Sleep Apnea and Overlapping Co-morbidities

NCT05558501
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Mild Intermittent Hypoxia, Sham MIH
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
30 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Sep 26, 2026, 4:49 PM EDT
Withdrawn Not applicable Interventional

Optimizing Treatment Effects on OSA-related Clinical and Patient-centered Outcomes Among Blacks

NCT03354520
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Tailored Videos, OSA Treatment, Standard Videos
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2022 · Synced Sep 26, 2026, 4:49 PM EDT
Completed Not applicable Interventional Results available

Early Warning System

NCT01741480
View directory record Official record
Conditions
Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Cancer, Diabetes Mellitus, Obstructive Sleep Apnea
Interventions
Early warning system monitoring., routine care
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 100 Years
Enrollment
571 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Sep 26, 2026, 4:49 PM EDT
Recruiting Not applicable Interventional

Home-based Under Mattress Monitor for OSA

NCT07186725
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSAS), Obstructive Sleep Apnea (SAOS)
Interventions
Under-mattress monitor, level 3 Home Sleep Apnea Test, Mandibular Advancement Device (MAD)
Device
Lead sponsor
Isabel Moreno Hay
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 26, 2026, 4:49 PM EDT
Completed Not applicable Interventional Results available

Comparison Study Using APAP With and Without SensAwake in Patients With OSA and PTSD

NCT02549508
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA), Post-Traumatic Stress Disorder (PTSD)
Interventions
AutoCPAP with SensAwake On, AutoCPAP with SensAwake Off
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Sep 26, 2026, 4:49 PM EDT
Completed Phase 4 Interventional Results available

Dexmedetomidine and Propofol in Children With History of Obstructive Sleep Apnea

NCT01344759
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Dexmedetomidine, Propofol
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Months to 25 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Sep 26, 2026, 4:49 PM EDT
Completed No phase listed Observational

A Study to Examine the Relationship Between Sleep Apnea and Cleft Lip/Palate

NCT00156442
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome, Cleft Lip/Palate
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
1 Year to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 11, 2010 · Synced Sep 26, 2026, 4:49 PM EDT
Not listed Phase 2 Interventional

Ketogenic Diet Treatment of Obesity With Co-morbid Type 2 Diabetes Mellitus and/or Obstructive Sleep Apnea

NCT02069197
View directory record Official record
Conditions
Obesity, Diabetes, Obstructive Sleep Apnea
Interventions
Ketogenic diet, Orlistat, Standardized diet
Other · Drug
Lead sponsor
Mid-Atlantic Epilepsy and Sleep Center, LLC
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 16, 2018 · Synced Sep 26, 2026, 4:49 PM EDT
Terminated Not applicable Interventional Results available

Effect of Upper Airway Stimulation on Vascular Function in Obstructive Sleep Apnea

NCT03051165
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Hypoglossal Nerve Stimulation Treatment Withdrawal
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Sep 26, 2026, 4:49 PM EDT
Withdrawn Not applicable Interventional

Evaluating the Efficacy of CPAP Therapy for the Treatment of Fatty Liver

NCT01849081
View directory record Official record
Conditions
Non-alcoholic Fatty Liver Disease
Interventions
CPAP, LIfestyle
Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Sep 26, 2026, 4:49 PM EDT
Not listed Not applicable Interventional

The Impact of Daily Sinus Irrigation on Nasal Symptoms in Continuous Positive Airway Pressure (CPAP) Users - A Pilot Study

NCT01121445
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
NeilMed nose and sinus irrigation
Device
Lead sponsor
Bridgeport Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Bridgeport, Connecticut
Source: ClinicalTrials.gov public record
Updated May 11, 2010 · Synced Sep 26, 2026, 4:49 PM EDT