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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:02 AM EDT

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Showing 265–288 of 1,491 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: TBI Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Physiology of Interregional Connectivity in the Human Brain

NCT03723434
View directory record Official record
Conditions
Healthy, Stroke, Traumatic Brain Injury, Multiple Sclerosis
Interventions
Single-pulse transcranial magnetic stimulation (spTMS), Paired associative stimulation (PAS), Repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 29, 2018 · Synced Oct 21, 2026, 4:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Therapeutic Resources for Attention Improvement With Neuroimaging for TBI

NCT02082509
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
8 Years to 16 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2018 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Overcoming Membrane Transporters to Improve CNS Drug Delivery - Improving Brain Antioxidants After Traumatic Brain Injury

NCT01322009
View directory record Official record
Conditions
Pediatric Traumatic Brain Injury
Interventions
Probenecid and N-acetyl cysteine, Placebo
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
2 Years to 18 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 15, 2016 · Synced Oct 21, 2026, 4:02 AM EDT
Not yet recruiting Not applicable Interventional

Feasibility and Acceptability of an LLM-based Chatbot for Family Caregivers: Evaluation Study

NCT07280650
View directory record Official record
Conditions
Caregivers
Interventions
LLM-based Chatbot
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional

HITT Device Pilot Testing for Traumatic Brain Injury

NCT03249818
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
HITT device
Device
Lead sponsor
Rebiscan, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 29, 2018 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional

Sleep Study Among Inpatients With TBI in an Acute Rehabilitation Hospital

NCT02236676
View directory record Official record
Conditions
Motor Learning in TBI
Interventions
Nap after rehearsal trials
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional

Stem Cell Transplant From Matched Unrelated or Partially Matched Related Donors

NCT00186225
View directory record Official record
Conditions
Blood Cancer, Blood and Marrow Transplant (BMT)
Interventions
ablative allogeneic hematopoietic cell transplantation
Procedure
Lead sponsor
Stanford University
Other
Eligibility
4 Weeks to 50 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1989 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2020 · Synced Oct 21, 2026, 4:02 AM EDT
Not listed Phase 2 Interventional

IRB-HSR# 14299: The Use of the Intrathoracic Pressure Regulator (ITPR) to Improve Cerebral Perfusion Pressure in Patients With Altered Intracranial Elastance

NCT01205607
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
ITPR -5 mm Hg then -9 mm Hg, ITPR -9 & then -5mm Hg
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 20, 2010 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Phase 2 Interventional Results available

Tau Imaging of Chronic Traumatic Encephalopathy

NCT02191267
View directory record Official record
Conditions
Chronic Traumatic Encephalopathy
Interventions
[F18]-T807, [F18]-Florbetapir, MRI/MRS, Genetic Analysis for Genetic Risk Score for Tau.
Radiation · Device · Genetic
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years to 69 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 17, 2018 · Synced Oct 21, 2026, 4:02 AM EDT
Completed No phase listed Observational

EYE-SYNC Concussion Classification Study

NCT04381767
View directory record Official record
Conditions
Concussion, Mild, Concussion; Eye, Concussion, Brain, Concussion, Severe, Brain Injuries, Concussion, Cerebral
Interventions
EYE-SYNC
Device
Lead sponsor
Sync-Think, Inc.
Industry
Eligibility
17 Years and older
Enrollment
1,303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Oct 21, 2026, 4:02 AM EDT
Not listed Not applicable Interventional

Online Intervention for Traumatic Brain Injury Wellbeing

NCT05115656
View directory record Official record
Conditions
Traumatic Brain Injury, Attention Impaired, Emotional Regulation
Interventions
Online group 1, Online group 2
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 6, 2023 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional

Improving Outcomes After Traumatic Injury: A Goal Management Approach

NCT01714531
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Telephone-Based Goal Management Training, Telephone-Based Attention-Control
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional

Brain Injury Inpatient Educational Intervention for Families and Caregivers

NCT01062243
View directory record Official record
Conditions
Traumatic Brain Injury, Acquired Brain Injury
Interventions
Brain Injury Education
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2013 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Results available

Non-Myeloablative Allogeneic Stem Cell Transplantation

NCT00525876
View directory record Official record
Conditions
Lymphoma
Interventions
Cyclophosphamide, Fludarabine, Rituximab, Alemtuzumab, Allogeneic Stem Cell Infusion
Drug · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Up to 70 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 7, 2011 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Phase 1 Interventional

Traumatic Brain Injury Peripheral Nerve Study

NCT01588691
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Eon-mini IPG (implantable pulse generator)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Poway, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 21, 2026, 4:02 AM EDT
Completed No phase listed Observational Results available

INTRuST Structured Assessment For Evaluation of TBI (SAFE-TBI)

NCT01554891
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
Not listed
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years to 60 Years
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Augusta, Maine • Manchester, New Hampshire + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Oct 21, 2026, 4:02 AM EDT
Active, not recruiting Phase 2 Interventional

Fludarabine and Total Body Irradiation 800 Centigray (cGy) or 1125 cGy For Allogeneic Stem Cell Transplant Using Graft Versus Host Disease Prophylaxis With Post-Transplant Cyclophosphamide and Tacrolimus, Without Mycophenolate Mofetil

NCT05256537
View directory record Official record
Conditions
Hematologic Neoplasms
Interventions
Omission of the drug mycophenolate mofetil
Other
Lead sponsor
Ronald Paquette
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Completed No phase listed Observational

The Impact of Community-based Wellness Programs on The Triple Aim

NCT02938130
View directory record Official record
Conditions
Spina Bifida, Cerebral Palsy, Spinal Cord Injury, Traumatic Brain Injury
Interventions
Wellness Programs
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
7 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Suspended Not applicable Interventional

Virtual Reality Treadmill Training in Individuals With Traumatic Brain Injury

NCT05721209
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
C-Mill with AR/VR Guidance, C-Mill without AR/VR Guidance, Zeno 3-Layer Walkway, Hunova
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Recruiting Phase 2 Interventional

Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History

NCT05446584
View directory record Official record
Conditions
Mild Cognitive Impairment, Amnestic Mild Cognitive Disorder, Amnestic Mild Cognitive Impairment, Mild Traumatic Brain Injury, Concussion, Brain
Interventions
High Definition Transcranial Direct Current Stimulation
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
55 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional

Evaluating the Effectiveness of Treatment for Metacognition in Moderate and Severe Traumatic Brain Injury

NCT03169647
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
Listening-based intervention
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 59 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 23, 2019 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Prevention of Traumatic Brain Injury in Youth and Adolescents

NCT01629121
View directory record Official record
Conditions
Focus of Study: Bicycle Helmet Wearing Compliance
Interventions
education intervention
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
5 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2013 · Synced Oct 21, 2026, 4:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

An Investigator Initiated Study to Evaluate the Effectiveness of Brain Network Activation (BNA™) Technology in the Management of Sport Related Concussion

NCT01963247
View directory record Official record
Conditions
Healthy, Minor Traumatic Brain Injury (TBI)
Interventions
Not listed
Lead sponsor
ElMindA Ltd
Industry
Eligibility
11 Years to 15 Years · Male only
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 9, 2015 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Results available

Using the Xbox Kinect for Chronic TBI

NCT02889289
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Xbox One Kinect Gaming
Other
Lead sponsor
Washington D.C. Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2017 · Synced Oct 21, 2026, 4:02 AM EDT