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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:55 PM EDT

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Showing 505–528 of 1,493 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: TBI Clear all
Completed No phase listed Observational Accepts healthy volunteers

Quantification of Balance in Acutely Concussed Athletes

NCT01661075
View directory record Official record
Conditions
mTBI, Concussion, Mild Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 30 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 9, 2017 · Synced Oct 22, 2026, 4:55 PM EDT
Completed Not applicable Interventional

Narrative Discourse Treatment Development

NCT05008419
View directory record Official record
Conditions
Traumatic Brain Injury, Neurogenic Communication Disorders
Interventions
Narrative discourse treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 22, 2026, 4:55 PM EDT
Completed No phase listed Observational

Wellness and Quality of Life Perceptions of People With Traumatic Brain Injury

NCT04794894
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
outpatient rehabilitation
Behavioral
Lead sponsor
Quality Living, Inc.
Other
Eligibility
19 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 22, 2026, 4:55 PM EDT
Recruiting No phase listed Observational

Recovery Among Older Adults Following Mild TBI

NCT07569354
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
65 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 22, 2026, 4:55 PM EDT
Recruiting Phase 4 Interventional

Buspirone and Melatonin for Depression Following Traumatic Brain Injury

NCT04400266
View directory record Official record
Conditions
Depression, Brain Injuries, Traumatic
Interventions
Buspirone, Mealatonin
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 22, 2026, 4:55 PM EDT
Not listed Phase 1 Interventional

ATCell™ Expanded Autologous, Adipose-Derived Mesenchymal Stem Cells Deployed Via Intravenous Infusion

NCT04744051
View directory record Official record
Conditions
Post-Concussion Syndrome
Interventions
50 Adipose Derived Stem Cell Infusion, 150 Adipose Derived Stem Cell Infusion, 300 Adipose Derived Stem Cell Infusion, Placebo Infusion
Drug
Lead sponsor
American CryoStem Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
La Mesa, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2023 · Synced Oct 22, 2026, 4:55 PM EDT
Completed Not applicable Interventional

Medical and Resource Facilitation Intervention After Traumatic Brain Injury

NCT03429322
View directory record Official record
Conditions
Brain Injuries, Traumatic, Family, Physician's Role
Interventions
Medical Care and Resource Facilitation, Usual Care
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
415 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Oct 22, 2026, 4:55 PM EDT
Not yet recruiting No phase listed Observational

Deployment of a Novel National Institute of Neurological Disorders and Stroke Clinical, Biomarker, Imaging, and Modifiers (CBI-M) Classification Framework for Emergency Department Patients With Glasgow Coma Scale 15 Traumatic Brain Injury (PIONEER-Prognosis)

NCT07858266
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
5
States / cities
Torrance, California • Ann Arbor, Michigan • Clinton Township, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 22, 2026, 4:55 PM EDT
Completed Phase 1 Interventional Results available

Delayed Versus Early Enoxaparin Prophylaxis After Traumatic Brain Injury (TBI)

NCT01014403
View directory record Official record
Conditions
Venous Thromboembolism, Traumatic Brain Injury
Interventions
enoxaparin, placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
2
States / cities
Dallas, Texas • Tyler, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2021 · Synced Oct 22, 2026, 4:55 PM EDT
Completed Not applicable Interventional

Cognitive-Communication Screening and Early Therapy for Adults With Mild TBI

NCT03230656
View directory record Official record
Conditions
Concussion, Mild Traumatic Brain Injury, Cognitive Communication Disorder
Interventions
Early cognitive-communication therapy
Other
Lead sponsor
Northern Arizona University
Other
Eligibility
18 Years to 65 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Flagstaff, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Oct 22, 2026, 4:55 PM EDT
Completed Phase 2 Interventional Results available

Propylene Glycol-Free Melphalan HCl (EVOMELA®) in Combination With Fludarabine and Total Body Irradiation Based Reduced Intensity Conditioning for Haploidentical Transplantation

NCT03159702
View directory record Official record
Conditions
Hematological Malignancy, Multiple Myeloma
Interventions
Evomela, Fludarabine, Total Body Irradiation, Haploidentical Hematopoietic Cell Transplantation
Drug · Radiation · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 22, 2026, 4:55 PM EDT
Completed No phase listed Observational

Epigenetic Effects on Traumatic Brain Injury Recovery

NCT04186429
View directory record Official record
Conditions
Traumatic Brain Injury, Orthopedic Injury
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
3 Years to 18 Years
Enrollment
401 participants
Timeline
2017 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 22, 2026, 4:55 PM EDT
Enrolling by invitation Not applicable Interventional

SMART-CPT for PTSD/Concussion Implementation

NCT06995612
View directory record Official record
Conditions
PTSD, Concussion, Mild
Interventions
SMART-CPT, CPT
Behavioral
Lead sponsor
San Diego Veterans Healthcare System
Federal
Eligibility
18 Years to 55 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 22, 2026, 4:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Telemedicine Brain Injury Coping Skills (BICS-T) Support Group for Brain Injury Survivors and Their Caregivers

NCT04371211
View directory record Official record
Conditions
Traumatic Brain Injury, Coping Skills
Interventions
Telemedicine Brain Injury Coping Skills
Behavioral
Lead sponsor
Rehabilitation Hospital of Indiana
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 22, 2026, 4:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Innovative Concussion Prevention Device

NCT02901028
View directory record Official record
Conditions
Concussion
Interventions
Laboratory testing, Blood and Urine Draws
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years to 25 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2016 · Synced Oct 22, 2026, 4:55 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Assessment of Traumatic Brain Injury Using Transcranial Magnetic Stimulated Evoked Potentials

NCT06963775
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Delphi-MD device (QuantalX Neuroscience Ltd., Saba Israel)
Device
Lead sponsor
Ramon Diaz-Arrastia
Other
Eligibility
18 Years and older
Enrollment
215 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 22, 2026, 4:55 PM EDT
Completed Not applicable Interventional

Building Emotional Self-Awareness Teletherapy (BEST)

NCT05623046
View directory record Official record
Conditions
Concussion, Mild, Concussion, Brain, Concussion, Severe, Concussion, Intermediate, Concussion; Syndrome, Concussion Injury of Cerebrum, Concussion with Brief Loss of Consciousness, Alexithymia
Interventions
Treatment
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Oct 22, 2026, 4:55 PM EDT
Not listed Not applicable Interventional

Theta Burst Stimulation for Headaches After Traumatic Brain Injury

NCT04906603
View directory record Official record
Conditions
Post-Traumatic Headache, Transcranial Magnetic Stimulation, Brain Injuries, Traumatic, Quality of Life
Interventions
Theta Burst Stimulation
Device
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Oct 22, 2026, 4:55 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of High-Intensity Gait Training Using a Treadmill on Locomotion Recovery in Traumatic Brain Injury Patients

NCT05622786
View directory record Official record
Conditions
Traumatic Brain Injury, Gait Disorders, Neurologic
Interventions
HIGT - physical rehab, Low intensity physical therapy
Other
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 19, 2024 · Synced Oct 22, 2026, 4:55 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Platelet Bioenergetics in TBI

NCT04271059
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
Not listed
Lead sponsor
Kevin Hatton
Other
Eligibility
18 Years to 50 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Oct 22, 2026, 4:55 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Remediation of Impaired Self-Regulation in Patients With Mild TBI

NCT02260570
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Tolcapone, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 50 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Oct 22, 2026, 4:55 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Disparity Driven Vergence in Mild Traumatic Brain Injury (mTBI)

NCT03529799
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
I-PAS Goggles
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 22, 2026, 4:55 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Imaging of Traumatic Brain Injury

NCT01196299
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 21, 2022 · Synced Oct 22, 2026, 4:55 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Speech in Noise Using Noninvasive Stimulation

NCT07176936
View directory record Official record
Conditions
Traumatic Brain Injury, Hearing Loss
Interventions
Cymba Conchae stimulation, Earlobe stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
25 Years to 55 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 22, 2026, 4:55 PM EDT