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ClinicalTrials.gov public records Last synced Oct 23, 2026, 10:45 AM EDT

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Showing 769–792 of 1,494 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: TBI Clear all
Not listed No phase listed Observational Accepts healthy volunteers

Cortical Excitability in Post-traumatic Epilepsy

NCT05517954
View directory record Official record
Conditions
Traumatic Brain Injury, Cortical Excitability, Epilepsy
Interventions
Not listed
Lead sponsor
Mid-Atlantic Epilepsy and Sleep Center, LLC
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 26, 2022 · Synced Oct 23, 2026, 10:45 AM EDT
Completed Phase 4 Interventional Results available

Simvastatin for mTBI

NCT01952288
View directory record Official record
Conditions
TBI-Traumatic Brain Injury
Interventions
simvastatin, Placebo Oral Tablet
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Oct 23, 2026, 10:45 AM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Heart Rate Variability Biofeedback Following Traumatic Brain Injury

NCT05913505
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
OSC-
Behavioral
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 23, 2026, 10:45 AM EDT
Completed Not applicable Interventional Results available

Enhanced Problem-Solving Training

NCT03759223
View directory record Official record
Conditions
Brain Concussion
Interventions
Enhanced Problem-Solving Training (E-PST), Healthy Living Messages (HLM), Enhanced Problem-Solving Training (E-PST) (non-randomized)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 23, 2026, 10:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Video Review of the Frequency and Assessment of Head Impacts During the FIFA World Cup 2022TM

NCT05629169
View directory record Official record
Conditions
Head Injury, Concussion, Brain Injuries, Traumatic Brain Injury
Interventions
No intervention applied - observational study only
Other
Lead sponsor
Federation Internationale de Football Association
Other
Eligibility
Male only
Enrollment
832 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Oct 23, 2026, 10:45 AM EDT
Completed No phase listed Observational

Testing Devices That Involve the Sense of Touch in Subjects With Traumatic Brain Injury

NCT01404494
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 23, 2026, 10:45 AM EDT
Completed Not applicable Interventional Results available

Brain Training to Enhance Frontal Lobe Reasoning

NCT01552473
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Brain Training Program 1, Brain Training Program 2
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
19 Years to 65 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 23, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Noninvasive Vagal Nerve Stimulation and Cognitive Rehabilitation

NCT06589362
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Transcutaneous auricular vagus active nerve stimulation, Transcutaneous auricular vagus sham nerve stimulation
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 23, 2026, 10:45 AM EDT
Enrolling by invitation Not applicable Interventional

Investigation of Neurocognitive Measures of Sport-Related Injury

NCT03414242
View directory record Official record
Conditions
Concussion, Brain
Interventions
Cervical spine musculature
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 30 Years
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 23, 2026, 10:45 AM EDT
Completed No phase listed Observational

Pilot Study of NeuroTriage Device in Patients with Potential Brain Injury And/or Impairment

NCT03761641
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Neurotriage
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 23, 2026, 10:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treatment Comparison for Undergraduate College Students With Traumatic Brain Injury

NCT04628741
View directory record Official record
Conditions
Traumatic Brain Injury, Concussion, Brain
Interventions
Dynamic Coaching Model, Apprenticeship Approach
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Oct 23, 2026, 10:45 AM EDT
Completed Not applicable Interventional

Home-Based, Online, Mindfulness and Cognitive Training for Soldiers and Veterans With TBI

NCT02922569
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training, Mindfulness Training, Traumatic Brain Injury Information Session
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 23, 2026, 10:45 AM EDT
Active, not recruiting Not applicable Interventional

Hypertonic Saline for Mild TBI in Pediatric Patients

NCT07060105
View directory record Official record
Conditions
Head Injury, Minor, Pediatric, Emergency Department Patient
Interventions
Hypertonic Saline ( 3% Sodium Chloride Saline), Normal Saline (0.9% NaCl)
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
8 Years to 17 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 23, 2026, 10:45 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Non-invasive Nerve Stimulation and Sleep

NCT04021537
View directory record Official record
Conditions
PTSD
Interventions
non-invasive nerve stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 23, 2026, 10:45 AM EDT
Completed Phase 2 Interventional

Peripheral Stem Cell Transplant, White Blood Cell Infusions, Chemotherapy, and Radiation Therapy in Treating Patients With Recurrent Metastatic Cervical or Vaginal Cancer

NCT00005941
View directory record Official record
Conditions
Cervical Cancer, Vaginal Cancer
Interventions
therapeutic allogeneic lymphocytes, cyclosporine, fludarabine phosphate, mycophenolate mofetil, peripheral blood stem cell transplantation, radiation therapy
Biological · Drug · Procedure + 1 more
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
Up to 64 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2005
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 2, 2010 · Synced Oct 23, 2026, 10:45 AM EDT
Completed No phase listed Observational

Evaluation and Diagnosis of Potential Research Subjects With Traumatic Brain Injury

NCT01287156
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
18 Years and older
Enrollment
1,328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 23, 2026, 10:45 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Bioness Integrated Therapy System (BITS) Touch Screen Technology to Improve Field Awareness

NCT04930822
View directory record Official record
Conditions
Stroke, Neurologic Disorder, Traumatic Brain Injury, Acquired Brain Injury
Interventions
Table Top Visual Intervention, Bioness Integrated Therapy System Visual Intervention
Other · Device
Lead sponsor
Gaylord Hospital, Inc
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Wallingford, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 23, 2026, 10:45 AM EDT
Completed No phase listed Observational

Evaluating a Novel Method of EEG Evoked Response Potential Analysis in Concussion Assessment

NCT03265912
View directory record Official record
Conditions
Concussion, Mild, TBI (Traumatic Brain Injury), Mild Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
ElMindA Ltd
Industry
Eligibility
15 Years to 50 Years
Enrollment
46 participants
Timeline
2017 – 2018
U.S. locations
2
States / cities
New York, New York • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Oct 23, 2026, 10:45 AM EDT
Completed Not applicable Interventional

Effectiveness of a Driving Intervention on Safe Community Mobility for Returning Combat Veterans

NCT02765672
View directory record Official record
Conditions
Traumatic Brain Injury (TBI), Post Traumatic Stress Disorder (PTSD)
Interventions
Driving Behavior Interview, Clinical Driving Assessment, Propensity for Angry Driving Scale, Community Integration Questionnaire, Satisfaction with Life, Fitness-to-Drive Screening Measure (FTDS), Simulated Driving Evaluation, Driving Safety Education, Occupational Therapy Driving Intervention (OT-DI), On-road driving test, Driving triggers evaluation
Behavioral · Other · Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 85 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 19, 2024 · Synced Oct 23, 2026, 10:45 AM EDT
Not yet recruiting Not applicable Interventional

Nature as Medicine for the Healing Brain: Utilization of a Nature-based Exposure Intervention for Decreasing Concussion Recovery Timeline and Symptom Load

NCT07642739
View directory record Official record
Conditions
Concussion (Diagnosis)
Interventions
Nature-based Guided Awareness Group, Standard Guided Awareness Group
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
14 Years to 35 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 23, 2026, 10:45 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Traumatic Brain Injury Feasibility Study (EPIC-011)

NCT02471625
View directory record Official record
Conditions
Traumatic Brain Injury, Controls
Interventions
ClearView Scanning
Device
Lead sponsor
Epic Research & Diagnostics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2015
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 20, 2015 · Synced Oct 23, 2026, 10:45 AM EDT
Completed Not applicable Interventional

rTMS for Cognitive Rehabilitation After TBI

NCT03642158
View directory record Official record
Conditions
Cognitive Impairment, Traumatic Brain Injury
Interventions
repetitive Transcranial Magnetic Stimulation
Device
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Oct 23, 2026, 10:45 AM EDT
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS) and Motor Training for Traumatic Brain Injury (TBI) Survivors

NCT01749735
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation, Armeo training
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Oct 23, 2026, 10:45 AM EDT
Completed Not applicable Interventional

Early Exercise to Improve Psychosocial Function After Pediatric Mild Traumatic Brain Injury

NCT04199247
View directory record Official record
Conditions
Brain Concussion, Pediatric, Mild Traumatic Brain Injury, Psychological
Interventions
Sub symptom aerobic exercise
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 18 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Oct 23, 2026, 10:45 AM EDT