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ClinicalTrials.gov public records Last synced Oct 24, 2026, 3:52 PM EDT

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Showing 913–936 of 1,494 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: TBI Clear all
Recruiting Not applicable Interventional

Remote Stimulation and Training to Advance Recovery From TBI in Seniors

NCT07332299
View directory record Official record
Conditions
Traumatic Brain Injury, Aging Related Cognitive Decline
Interventions
Active tDCS and Cognitive Training Intervention, Sham tDCS and Cognitive Training Intervention
Combination Product
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 24, 2026, 3:52 PM EDT
Completed Not applicable Interventional

Modified Story Memory Technique (mSMT) in Persons With TBI

NCT04056312
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Group Memory retraining exercises, Placebo controlled group memory exercise training
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 24, 2026, 3:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Concussion Prevention in Female Soccer Athletes

NCT03014492
View directory record Official record
Conditions
Concussion, Mild, Concussion, Brain
Interventions
Q Collar
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
14 Years to 19 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 24, 2026, 3:52 PM EDT
Terminated Not applicable Interventional Results available

Galvanic Vestibular Stimulation and Motor Training in Traumatic Brain Injury Survivors

NCT01749800
View directory record Official record
Conditions
TBI, Attention Deficits, Motor Impairments
Interventions
GVS, Sham GVS, Armeo Spring
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Oct 24, 2026, 3:52 PM EDT
Not yet recruiting No phase listed Observational

Deployment of a Novel National Institute of Neurological Disorders and Stroke Clinical, Biomarker, Imaging, and Modifiers (CBI-M) Classification Framework for Emergency Department Patients With Glasgow Coma Scale 15 Traumatic Brain Injury (PIONEER-Prognosis)

NCT07858266
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
5
States / cities
Torrance, California • Ann Arbor, Michigan • Clinton Township, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 24, 2026, 3:52 PM EDT
Not listed Phase 3 Interventional

Hyperbaric Oxygen Treatment to Treat Mild Traumatic Brain Injury (mTBI)/Persistent Post-Concussion Syndrome (PPCS)

NCT02089594
View directory record Official record
Conditions
Post-Concussion Syndrome, Traumatic Brain Injury
Interventions
Hyperbaric Oxygen, No Hyperbaric Oxygen
Drug
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 24, 2026, 3:52 PM EDT
Not listed Not applicable Interventional

Narrative Comprehension by People With Acquired Brain Injury

NCT03309930
View directory record Official record
Conditions
Aphasia, Traumatic Brain Injury
Interventions
Comprehension Acquired Brain Injury
Behavioral
Lead sponsor
Miami University
Other
Eligibility
19 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Oxford, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 16, 2017 · Synced Oct 24, 2026, 3:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Addressing Attitudes to Improve Use of Protective Headwear in Older Adults

NCT01582464
View directory record Official record
Conditions
Injury of Unknown Intent Due to Fall From Height, Traumatic Brain Injury
Interventions
Social Marketing for protective headgear
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
65 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Multiple, California
Source: ClinicalTrials.gov public record
Updated May 9, 2016 · Synced Oct 24, 2026, 3:52 PM EDT
Terminated Not applicable Interventional Results available

Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion

NCT01824576
View directory record Official record
Conditions
Head Injury, Intracranial Pathology, Compromised Cerebral Perfusion
Interventions
ITPR
Device
Lead sponsor
Advanced Circulatory Systems
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
Denver, Colorado • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 27, 2017 · Synced Oct 24, 2026, 3:52 PM EDT
Recruiting Phase 1 Interventional

TLI, TBI, ATG & Hematopoietic Stem Cell Transplantation and Recipient T Regs Therapy in Living Donor Kidney Transplantation

NCT03943238
View directory record Official record
Conditions
Living Donor Kidney Transplantation
Interventions
Infusion of Donor Hematopoetic Stem Cells and Recipient Tregs
Biological
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
2
States / cities
Palo Alto, California • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 24, 2026, 3:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bright Light Therapy for Treatment of Sleep Problems Following Mild Traumatic Brain Injury

NCT02374918
View directory record Official record
Conditions
Concussion, Mild, Post-Concussion Symptoms, Sleep Problems
Interventions
mTBI wavelength-1 bright light, mTBI wavelength-2 bright light, HC wavelength-1 bright light, HC wavelength-2 bright light
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 50 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 24, 2021 · Synced Oct 24, 2026, 3:52 PM EDT
Recruiting Not applicable Interventional

Promoting Neuroplastic Changes of Patients With TBI

NCT06465290
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Motor relearning training with wearable ankle robot, Passive stretching with wearable ankle robot, Gamed-based active movement training with wearable ankle robot, Passive movement with limited wearable ankle robot, Active movement training with limited wearable ankle robot, Ankle/Wrist torque and motion measurement with limited wearable ankle/wrist robot
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
30 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 24, 2026, 3:52 PM EDT
Recruiting Not applicable Interventional

Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic Brain Injury

NCT03655782
View directory record Official record
Conditions
MTBI - Mild Traumatic Brain Injury
Interventions
PATH + DigitMemory (DM) neurotraining
Behavioral
Lead sponsor
Perception Dynamics Institute
Industry
Eligibility
18 Years to 60 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
San Diego, California • Solana Beach, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 24, 2026, 3:52 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

mTBI Identification and Monitoring Through Retinal Scanning

NCT06142435
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
Head and Intraocular Trauma Tool
Device
Lead sponsor
Rebiscan, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 24, 2026, 3:52 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

A Feasibility Study in Combat Athletes With Mild Traumatic Brain Injury

NCT06901310
View directory record Official record
Conditions
Mild Traumatic Brain Injury (mTBI), Brain Injury, Concussion
Interventions
Hyberbaric Oxygen Therapy
Device
Lead sponsor
Michael Harl
Other
Eligibility
18 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Marshfield, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Oct 24, 2026, 3:52 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury

NCT05762796
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury, Motor Disorders, Cognitive Impairment
Interventions
tDCS in Youth with mild traumatic brain injury
Device
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
10 Years to 15 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 24, 2026, 3:52 PM EDT
Not yet recruiting Not applicable Interventional

Sleep MAPP in the Polytrauma/TBI System of Care

NCT07886398
View directory record Official record
Conditions
Insomnia Disorder, Mild Traumatic Brain Injury
Interventions
Sleep MAPP Care Pathway
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
2
States / cities
Aurora, Colorado • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 24, 2026, 3:52 PM EDT
Completed Not applicable Interventional Results available

Improving Functions in MTBI Patients With Headache by rTMS

NCT01948947
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 50 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2018 · Synced Oct 24, 2026, 3:52 PM EDT
Not listed No phase listed Observational

Advanced MRI in Blast-related TBI

NCT00785304
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Oct 24, 2026, 3:52 PM EDT
Completed Phase 1 Interventional

Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders

NCT00010335
View directory record Official record
Conditions
Systemic Sclerosis, Systemic Lupus Erythematosus, Dermatomyositis, Juvenile Rheumatoid Arthritis, Autoimmune Diseases
Interventions
Stem Cell Transplantation, CD34 selection
Procedure · Device
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
2 Years to 18 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2011
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 6, 2015 · Synced Oct 24, 2026, 3:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Integrated Eye Tracking and Neural Monitoring for TBI: Optimization

NCT03451058
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 55 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2022 · Synced Oct 24, 2026, 3:52 PM EDT
Recruiting Not applicable Interventional

Rapid Treatment of PTSD With Accelerated Non-Invasive Brain Stimulation

NCT06544408
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Traumatic Brain Injury
Interventions
Cool B70 AP Coil - Active (dl-PFC), Cool B70 AP Coil- Sham (dl-PFC), Cool D-B80 AP Coil - Active (dm-PFC), Cool D-B80 AP Coil - Sham (dm-PFC), Cool B70 Treatment Coil - Active Only
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 65 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 24, 2026, 3:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aerobic Exercise for Concussion

NCT02959216
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Acute Brain Injury, Brain Concussion
Interventions
Aerobic Exercise, Stretching Exercise
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
13 Years to 18 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
3
States / cities
Boston, Massachusetts • Buffalo, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Oct 24, 2026, 3:52 PM EDT
Completed No phase listed Observational

EyeBOX Concussion Study and Registry

NCT03966404
View directory record Official record
Conditions
Concussion, Brain, Mild Traumatic Brain Injury
Interventions
EyeBOX device
Diagnostic Test
Lead sponsor
Oculogica, Inc.
Industry
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced Oct 24, 2026, 3:52 PM EDT