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ClinicalTrials.gov public records Last synced Oct 26, 2026, 10:50 PM EDT

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Showing 1105–1128 of 1,494 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: TBI Clear all
Recruiting Not applicable Interventional

Emotional Awareness Therapy Study

NCT07624825
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
TREAT-A, TREAT-B
Behavioral
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Edison, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 26, 2026, 10:50 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Longitudinal Assessment of Traumatic Microvascular Injury-2

NCT05725993
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 26, 2026, 10:50 PM EDT
Completed Phase 2 Interventional Results available

Chemotherapy, Irradiation, Cell Infusions, and Interleukin-2 to Treat Metastatic Melanoma

NCT00314106
View directory record Official record
Conditions
Metastatic Melanoma
Interventions
Melanoma Reactive TIL, Cyclophosphamide, IL-2, Fludarabine, 1200 total body irradiation (TBI)
Biological · Drug · Radiation
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 18, 2012 · Synced Oct 26, 2026, 10:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predicting Cognitive and Emotional Health From Neurocircuitry Following TBI

NCT01803048
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Arizona
Other
Eligibility
20 Years to 45 Years
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 26, 2026, 10:50 PM EDT
Completed Not applicable Interventional Results available

Memantine for Neuroprotection and Cognitive Enhancement Following Traumatic Brain Injury

NCT02240589
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Memantine, Placebo
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Oct 26, 2026, 10:50 PM EDT
Completed No phase listed Observational

Structural and Functional Neuroimaging Studies of Combat Veterans

NCT01296126
View directory record Official record
Conditions
Traumatic Brain Injury, PTSD
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Oct 26, 2026, 10:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stroke and Traumatic Acute Brain Injury Line Indicator System for Emergent Recognition (STABILISER-I)

NCT02514902
View directory record Official record
Conditions
Ischemic Stroke, Hemorrhagic Stroke, Traumatic Brain Injury
Interventions
Lateral Flow Device
Device
Lead sponsor
Justin Fraser
Other
Eligibility
21 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 26, 2026, 10:50 PM EDT
Completed Not applicable Interventional

Fast MR for Young Children With Traumatic Brain Injury

NCT02392975
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
Fast MR, Computed Tomography
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Up to 72 Months
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 24, 2019 · Synced Oct 26, 2026, 10:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Community-based Implementation of Online EmReg

NCT05933629
View directory record Official record
Conditions
Traumatic Brain Injury, Emotion Regulation
Interventions
Online EmReg, Consultation Sessions
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 26, 2026, 10:50 PM EDT
Recruiting Phase 2 Interventional

Cannabidiol as a Treatment for PTSD and PTSD Comorbid With TBI

NCT04550377
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Traumatic Brain Injury
Interventions
Cannabidiol, Placebo
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 26, 2026, 10:50 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

The TCU Division I Collegiate Athlete Study

NCT07006051
View directory record Official record
Conditions
Orthopaedic Injuries, Concussion (Diagnosis)
Interventions
Exposed group
Other
Lead sponsor
Texas Christian University
Other
Eligibility
17 Years to 30 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 26, 2026, 10:50 PM EDT
Recruiting Not applicable Interventional

Postural Motor Activation Deficits After mTBI; Translating Laboratory Findings to Clinical Care

NCT07549529
View directory record Official record
Conditions
Mild Traumatic Brain Injury (mTBI), Concussion, Mild Traumatic Brain Injury
Interventions
Motor Activation Physical Therapy for mTBI, Standard of Care Physical Therapy for mTBI
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Portland, Oregon • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 26, 2026, 10:50 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Sildenafil for Cerebrovascular Dysfunction in Chronic Traumatic Brain Injury.

NCT01762475
View directory record Official record
Conditions
Traumatic Brain Injury, Post-concussive Syndrome
Interventions
Sildenafil
Drug
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 55 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 1, 2016 · Synced Oct 26, 2026, 10:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Evaluation of VA's Traumatic Brain Injury (TBI) Clinical Reminder and Comprehensive TBI Evaluation (CTBIE)

NCT00852527
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
456 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
3
States / cities
Tucson, Arizona • Hines, Illinois • Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 26, 2026, 10:50 PM EDT
Withdrawn Early Phase 1 Interventional

Evaluation of the Efficacy of Sodium Oxybate (Xyrem®) in Treatment of Post-traumatic Narcolepsy and Post-traumatic Hypersomnia

NCT03626727
View directory record Official record
Conditions
Hypersomnia, Narcolepsy, Traumatic Brain Injury
Interventions
Sodium Oxybate Oral Solution [Xyrem]
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Oct 26, 2026, 10:50 PM EDT
Recruiting Phase 1 Interventional

Targeted Immunotherapy After Myeloablative TBI-Based Conditioning & AlloHCT in CAYA With High Risk T-Cell ALL & Lymphoma

NCT04972942
View directory record Official record
Conditions
T-cell Acute Lymphoblastic Leukemia, T-Cell Acute Lymphoblastic Lymphoma
Interventions
Daratumumab
Drug
Lead sponsor
New York Medical College
Other
Eligibility
Up to 39 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
16
States / cities
Phoeniz, Arizona • Loma Linda, California • Los Angeles, California + 13 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 26, 2026, 10:50 PM EDT
Completed Not applicable Interventional Results available

Sub-Threshold Exercise Treatment for Adolescents With Sports Related Concussion

NCT02710123
View directory record Official record
Conditions
Brain Injury, Concussion
Interventions
Sub-Threshold exercise prescription, Structured stretching prescription
Other
Lead sponsor
University at Buffalo
Other
Eligibility
10 Years to 18 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 26, 2026, 10:50 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Effects of Multiple Concussions in Retired NHL Players

NCT02746523
View directory record Official record
Conditions
Cognitive Deficits, Proprioceptive Disorders
Interventions
Sensory Organization Test, Biomarkers, Conners' Adult ADHD Rating Scale (CAARS), Depression Scale, Cognitive Assessment
Other · Genetic
Lead sponsor
New York Institute of Technology
Other
Eligibility
40 Years to 80 Years · Male only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2017 · Synced Oct 26, 2026, 10:50 PM EDT
Completed Not applicable Interventional

Mindfulness and Yoga Training for Athletes With Concussion (MYTAC)

NCT03304327
View directory record Official record
Conditions
Concussion
Interventions
Mindfulness and Yoga Training
Behavioral
Lead sponsor
Duke University
Other
Eligibility
15 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Oct 26, 2026, 10:50 PM EDT
Completed Not applicable Interventional

Improving New Learning and Memory in School Aged Children

NCT04741360
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Modified Story Memory Technique
Other
Lead sponsor
Kessler Foundation
Other
Eligibility
9 Years to 17 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Oct 26, 2026, 10:50 PM EDT
Withdrawn Not applicable Interventional

Exercise Training in Depressed Traumatic Brain Injury Survivors

NCT01805479
View directory record Official record
Conditions
Depression, Traumatic Brain Injury
Interventions
aerobic exercise, stretching and flexibility program
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
14 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 21, 2015 · Synced Oct 26, 2026, 10:50 PM EDT
Recruiting No phase listed Observational

Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders

NCT07493096
View directory record Official record
Conditions
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder), Cerebral Palsy (CP), Cerebral Palsy Hemiparetic Cerebral Palsy Spasticity Gait Disorders, Neurologic Postural Balance Impairment, Cerebral Palsy Infantile, Cerebral Palsy Spastic Hemiplegic, Cerebral Palsy, Dyskinetic, Autism Spectrum Disorder, Autism Spectrum Disorder (ASD, Hypoxic Ischemic Encephalopathy, Hypoxic Ischemic Encephalopathy (HIE), Traumatic Brain Injury (TBI), Sensory Processing Disorder, Chromosomal Abnormalities, Genetic Disorders, Down Syndrome (Trisomy 21), Fragile X Syndrome (FXS), RETT Syndrome With Proven MECP2 Mutation, Williams Syndrome, 22q11.2 Deletion Syndrome, Sensorimotor Integration
Interventions
Not listed
Lead sponsor
Healing Hope International
Other
Eligibility
4 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2036
U.S. locations
1
States / cities
The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 26, 2026, 10:50 PM EDT
Not yet recruiting Phase 2 Interventional

Ketamine Treatment for PTSD and MDD in TBI

NCT06228391
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder, Major Depressive Disorder, Traumatic Brain Injury
Interventions
IV ketamine, Midazolam
Drug
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Oct 26, 2026, 10:50 PM EDT
Recruiting Phase 3 Interventional

Quetiapine to Reduce Post Concussive Syndrome After Mild Traumatic Brain Injury (mTBI)

NCT06333990
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Quetiapine Fumarate, TAU
Drug
Lead sponsor
Foundation for Advancing Veterans' Health Research
Other
Eligibility
18 Years to 65 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Albuquerque, New Mexico • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 26, 2026, 10:50 PM EDT