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ClinicalTrials.gov public records Last synced Oct 27, 2026, 12:41 AM EDT

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Showing 1129–1152 of 1,494 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: TBI Clear all
Completed Not applicable Interventional

Active Injury Management (AIM) After Pediatric Concussion

NCT03869970
View directory record Official record
Conditions
Brain Concussion
Interventions
REST, ACTIVITY, mHEALTH
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
11 Years to 24 Years
Enrollment
237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 15, 2023 · Synced Oct 27, 2026, 12:41 AM EDT
Completed Early Phase 1 Interventional

Ketogenic Diet for Traumatic Brain Injury

NCT03982602
View directory record Official record
Conditions
Traumatic Brain Injury, Ketogenic Dieting
Interventions
Ketogenic diet
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 27, 2026, 12:41 AM EDT
Terminated Phase 3 Interventional Results available

Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiation

NCT01366612
View directory record Official record
Conditions
Myeloid Malignancies, Acute Myelogenous Leukemia, Chronic Myelogenous Leukemia, Myeloproliferative Disorders, Myelodysplastic Syndrome
Interventions
Fludarabine and Busulfan plus/minus Total Body Irradiation (low dose), Fludarabine and Busulfan + Low Dose Total Body Irradiation (LD TBI)
Drug
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years to 70 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2020
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 27, 2026, 12:41 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

LearningRx Cognitive Training for Brain Injury

NCT02918994
View directory record Official record
Conditions
Traumatic Brain Injury (TBI), Acquired Brain Injury, Post COVID-19 Cognitive Impairment
Interventions
LearningRx cognitive training
Behavioral
Lead sponsor
Gibson Institute of Cognitive Research
Industry
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2027
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 27, 2026, 12:41 AM EDT
Not listed No phase listed Observational

Follow-up of MTBI Patients Discharged from the ED Using Standard Clinical Triage Including BrainScope One

NCT04279431
View directory record Official record
Conditions
TBI (Traumatic Brain Injury), Concussion, Brain, MTBI - Mild Traumatic Brain Injury, Closed Head Injury
Interventions
EEG Recording, Neurocognitive Tests, Clinician Evaluation, 22-item CSI
Device · Other
Lead sponsor
BrainScope Company, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
660 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
7
States / cities
Detroit, Michigan • Royal Oak, Michigan • Troy, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Oct 27, 2026, 12:41 AM EDT
Withdrawn Not applicable Interventional

Wii Fit Balance Training Compared to Traditional Balance Training in Patients With SCI/TBI/CVA

NCT01438671
View directory record Official record
Conditions
Distorted; Balance
Interventions
Nintendo Wii Fit, Traditional balance training
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Mount Vernon, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Oct 27, 2026, 12:41 AM EDT
Not listed Not applicable Interventional

Using Virtual Reality to Improve Job Reentry in Adults With TBI

NCT04820634
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Virtual Reality Job Interview Training, Wonderworks
Other
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 27, 2026, 12:41 AM EDT
Terminated Phase 2 Interventional Results available

Effects of Huperzine A in Treatment of Moderate to Severe TBI

NCT01676311
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Huperzine A, Placebo
Drug
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Oct 27, 2026, 12:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of Quality of Life Tool for TBI

NCT00714428
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
485 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
4
States / cities
Palo Alto, California • Tampa, Florida • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 7, 2015 · Synced Oct 27, 2026, 12:41 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Physiology of Interregional Connectivity in the Human Brain

NCT03723434
View directory record Official record
Conditions
Healthy, Stroke, Traumatic Brain Injury, Multiple Sclerosis
Interventions
Single-pulse transcranial magnetic stimulation (spTMS), Paired associative stimulation (PAS), Repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 29, 2018 · Synced Oct 27, 2026, 12:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessment and Rehabilitation of Central Sensory Impairments for Balance in mTBI

NCT02748109
View directory record Official record
Conditions
Brain Injury
Interventions
Vestibular Rehabilitation + audio biofeedback, Vestibular Rehabilitation
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 60 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 27, 2026, 12:41 AM EDT
Recruiting Not applicable Interventional

Goal-oriented Telehealth Rehabilitation of Executive Functioning for Veterans With Chronic TBI

NCT07190365
View directory record Official record
Conditions
Mild to Moderate Traumatic Brain Injury, Cognitive Rehabilitation, Veteran
Interventions
GOALS TH, EDU TH
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 27, 2026, 12:41 AM EDT
Completed Not applicable Interventional

Autologous Transplant Using Dose-Escalated Total Body Irradiation & Cyclophosphamide & Palifermin for NHL

NCT03042585
View directory record Official record
Conditions
Relapsed Non Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma
Interventions
Total body irradiation
Radiation
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Oct 27, 2026, 12:41 AM EDT
Completed Not applicable Interventional Results available

Traditional Balance vs Vibrotactile Feedback Training for Vestibular Rehabilitation

NCT01672658
View directory record Official record
Conditions
Traumatic Brain Injury, Vestibular Deficits
Interventions
Sensory Kinetics Balance System, Traditional Vestibular Rehabilitation
Device · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 4, 2016 · Synced Oct 27, 2026, 12:41 AM EDT
Terminated Phase 2 Interventional Results available

Flu,Alemtuzumab,and TBI Followed By Donor Stem Cell Chronic Phase CML

NCT00416884
View directory record Official record
Conditions
Leukemia
Interventions
Campath, Fludarabine, Total Body Irradiation (TBI), T-Cell Deplete
Drug · Radiation · Other
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
4 Years to 75 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 27, 2017 · Synced Oct 27, 2026, 12:41 AM EDT
Not listed Not applicable Interventional

PoNS Clinical Experience Program (TBI)

NCT03852732
View directory record Official record
Conditions
Mild to Moderate Traumatic Brain Injury
Interventions
PoNS Treatment
Device
Lead sponsor
Helius Medical Inc
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 27, 2026, 12:41 AM EDT
Not listed Not applicable Interventional

Online Treatment Recovery Assistance for Concussion in Kids

NCT05065099
View directory record Official record
Conditions
Concussion, MTBI - Mild Traumatic Brain Injury
Interventions
Online Treatment Recovery Assistance for Concussion in Kids (OnTRACK)
Device
Lead sponsor
Children's National Research Institute
Other
Eligibility
8 Years to 17 Years
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Oct 27, 2026, 12:41 AM EDT
Completed Phase 3 Interventional

Multicenter Evaluation of Memory Remediation After TBI With Donepezil

NCT02255799
View directory record Official record
Conditions
Traumatic Brain Injury, Memory Deficits
Interventions
Donepezil, Placebo
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
4
States / cities
Indianapolis, Indiana • Charlestown, Massachusetts • Elkins Park, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 27, 2026, 12:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hematopoietic Stem Cell Transplantation for Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using Total Body Irradiation, Cyclophosphamide and Fludarabine

NCT00595127
View directory record Official record
Conditions
Fanconi Anemia
Interventions
Cyclophosphamide, Fludarabine, Total body irradiation (TBI)
Drug · Radiation
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Oct 27, 2026, 12:41 AM EDT
Not yet recruiting No phase listed Observational

Safety and Outcomes of MUSE Stem Cell Therapy in Individuals With Traumatic Brain Injury

NCT07326059
View directory record Official record
Conditions
Traumatic Brain Injury, Traumatic Brain Injury (TBI) Patients, Traumatic Brain Injury (TBI); Concussion, Initial Encounter, Traumatic Brain Injury (TBI); Concussion, Subsequent Encounter, Traumatic Brain Injury With Brief Loss of Consciousness, Traumatic Brain Injury With Persistent Cognitive Deficits
Interventions
MUSE Stem Cell Therapy
Biological
Lead sponsor
Healing Hope International
Other
Eligibility
6 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2036
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 27, 2026, 12:41 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

CDP-Choline and Working Memory After TBI: A Neuroimaging Study

NCT00727246
View directory record Official record
Conditions
Brain Injuries
Interventions
CDP-Choline, Placebo
Drug
Lead sponsor
Patricia M. Arenth
Other
Eligibility
18 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 28, 2017 · Synced Oct 27, 2026, 12:41 AM EDT
Enrolling by invitation Not applicable Interventional

Investigation of Neurocognitive Measures of Sport-Related Injury

NCT03414242
View directory record Official record
Conditions
Concussion, Brain
Interventions
Cervical spine musculature
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 30 Years
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 27, 2026, 12:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Can Early Initiation of Rehabilitation With Wearable Sensor Technology Improve Outcomes in mTBI?

NCT03479541
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Balance; Distorted, Gait, Unsteady, Quality of Life, Veterans
Interventions
Timing of Rehabilitation, Biofeedback
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 60 Years
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Oct 27, 2026, 12:41 AM EDT
Terminated Not applicable Interventional

Improving Functional Ability in Chronic TBI With Intensive Rehabilitation Robotic Gait Training

NCT03438409
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
Robotic gait training
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 6, 2018 · Synced Oct 27, 2026, 12:41 AM EDT