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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: TEETH EXTRACTION Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Wound Healing Following Tooth Extraction and Ridge Preservation Using OsteoGen®

NCT07154693
View directory record Official record
Conditions
Tooth Extraction
Interventions
Combination 70% FDBA and 30% DFDBA, OsteoGen Plug
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 89 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®

NCT03659617
View directory record Official record
Conditions
Tooth Loss
Interventions
xenograft (BioOss Collagen)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 95 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Jul 23, 2026, 12:44 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

NCT07095556
View directory record Official record
Conditions
Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management, Tooth Extraction Site Healing
Interventions
Low-level laser therapy
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Healing Time on New Bone Formation Following Tooth Extraction and Ridge Preservation With Demineralized Freeze-Dried Bone Allograft

NCT02154386
View directory record Official record
Conditions
Bone Augmentation
Interventions
Ridge preservation using DFDBA
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 89 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Genetic Basis For Variation In NSAID Analgesia In A Clinical Model Of Acute Pain

NCT00115752
View directory record Official record
Conditions
Pain
Interventions
Valdecoxib, COX Inhibitor
Drug
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
7 Years to 35 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Study Testing Ketamine Sublingual Wafer After Wisdom Tooth Extraction

NCT02356965
View directory record Official record
Conditions
Pain
Interventions
Ketamine, Placebo (for Ketamine)
Drug
Lead sponsor
iX Biopharma Ltd.
Other
Eligibility
18 Years to 38 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 25, 2015 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Phase 2 Interventional Results available

Study of Long-Acting Acetaminophen in Postoperative Dental Pain

NCT01960114
View directory record Official record
Conditions
Dental Pain
Interventions
Acetaminophen ER, Placebo
Drug
Lead sponsor
McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.
Industry
Eligibility
17 Years to 45 Years
Enrollment
403 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 9, 2015 · Synced Jul 23, 2026, 12:44 PM EDT
Not yet recruiting Not applicable Interventional

NeuroCuple to Mitigate Post-Wisdom Teeth Extraction Opioid Risks

NCT07461506
View directory record Official record
Conditions
Wisdom Teeth, Wisdom Teeth Extraction or Jaw Implant
Interventions
NEUROCUPLE™ Patch, Sham Patch
Device
Lead sponsor
nCap Medical
Industry
Eligibility
18 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jul 23, 2026, 12:44 PM EDT
Terminated Phase 2 Interventional

Safety and Efficacy Study of NTC-510 to Treat Pain Following Dental Surgery of Third Molars

NCT02161354
View directory record Official record
Conditions
Dental Pain
Interventions
NTC-510 capsules, Placebo Capsules, NTC-510A Capsules
Drug
Lead sponsor
NanoSHIFT LLC
Industry
Eligibility
18 Years to 45 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 22, 2017 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Histological Comparison of Ridge Preservation Using Mineralized FDBA Alone Versus a Combined Mineralized-Demineralized Freeze Dried Bone Allograft

NCT01924390
View directory record Official record
Conditions
Tooth Extraction
Interventions
Mineralized freeze-dried bone allograft alone, Combination of Mineralized and demineralized freeze-dried bone allograft alone
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2014 · Synced Jul 23, 2026, 12:44 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Use of Dental Pulp Tissue as an Autogenous Graft for Ridge Augmentation

NCT03943849
View directory record Official record
Conditions
Tooth Loss
Interventions
Particulate bone graft, Autogenous dental pulp tissue, Resorbable collagen membrane, Suture
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Jul 23, 2026, 12:44 PM EDT
Withdrawn Not applicable Interventional

Study of Hemostatic Efficacy of the HemCon Dental Dressing in a Population Treated With Anticoagulant Medications

NCT00707564
View directory record Official record
Conditions
Tooth Extractions
Interventions
HemCon Dental Dressing, Gauze with pressure
Device
Lead sponsor
HemCon Medical Technologies, Inc
Industry
Eligibility
14 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
2
States / cities
Milwaukie, Oregon • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 23, 2012 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A 14 Weeks Longitudinal Study to Investigate the Effect of Leukocyte- Platelet Rich Fibrin Plug on the Quality of the Newly Formed Bone in Ridge Preservation Procedure Following a Tooth Extraction. It is a Clinical, Radiographic and Histomorphometric Study.

NCT03487718
View directory record Official record
Conditions
Alveolar Ridge Preservation, Tooth Extraction
Interventions
Leukocyte platelet rich fibrin plug + d-PTFE membrane, d-PTFE membrane
Biological · Device
Lead sponsor
Firas Al Yafi
Other
Eligibility
18 Years to 80 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 23, 2021 · Synced Jul 23, 2026, 12:44 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Evaluation of Implants Placed Immediately or Delayed Into Extraction Sites

NCT00067392
View directory record Official record
Conditions
Dental Caries
Interventions
Dental Implant
Procedure
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
21 Months to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 8, 2010 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Phase 2 Interventional

This is a Study Evaluating the Efficacy and Safety of LTG-001 for Acute Pain After Surgical Removal of Impacted Third Molars

NCT06774625
View directory record Official record
Conditions
Acute Pain, Postoperative
Interventions
LTG-001 High Dose, LTG-001 Mid Dose, LTG-001 Low Dose, Placebo, Suzetrigine
Drug · Other
Lead sponsor
Latigo Biotherapeutics
Industry
Eligibility
18 Years to 50 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Phase 1 Interventional

Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction

NCT03893175
View directory record Official record
Conditions
Impacted Third Molar Tooth, Pain, Acute
Interventions
Ibuprofen, Acetaminophen, Placebo, Oxycodone
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 64 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ridge Preservation Following Tooth Extraction Using Porcine and Bovine Xenograft Materials

NCT02802319
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
Porcine Xenograft (Zcore), Bovine Xenograft (Bio-Oss)
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 89 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Temporary Anchorage Devices for Ridge Preservation

NCT03205800
View directory record Official record
Conditions
Ridge Preservation
Interventions
Mini-screw
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Jul 23, 2026, 12:44 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Immediate Implant Placement Using Volume-Stable Collagen Matrix Combined With rhPDGF-BB

NCT06038695
View directory record Official record
Conditions
Tooth Extraction, Immediate Implant Placement
Interventions
Xenogeneic Volume-Stable Collagen (VCMX) graft with growth factor-BB
Device
Lead sponsor
I-Ching Wang
Other
Eligibility
18 Years to 95 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Jul 23, 2026, 12:44 PM EDT
Completed No phase listed Observational

Diagnosis, Evaluation and Treatment of Patients in Need of Third Molar Removal

NCT00316485
View directory record Official record
Conditions
Wisdom Teeth
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
18 Years to 50 Years
Enrollment
718 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Zimmer Puros® Allograft vs. Creos™ Allograft for Alveolar Ridge Preservation

NCT02444052
View directory record Official record
Conditions
Alveolar Bone Grafting, Allograft, Dental Extraction, Dental Implant, Socket Preservation
Interventions
Zimmer Puros Cancellous Allograft, Nobel Biocare Creos Cancellous Allograft
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 1, 2018 · Synced Jul 23, 2026, 12:44 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Comparative Volumetric Assessment of Alveolar Ridge Preservation Utilizing Different Bone Grafting Materials

NCT02532543
View directory record Official record
Conditions
Tooth Fractures, Tooth Injuries, Tooth Diseases
Interventions
Allograft, Membrane, Alloplast, Membrane, Xenograft, Membrane, Membrane
Biological
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 8, 2019 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Phase 2 Interventional

Local Flurbiprofen to Treat Pain Following Wisdom Tooth Extraction

NCT00001724
View directory record Official record
Conditions
Pain
Interventions
Flurbiprofen
Drug
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 23, 2026, 12:44 PM EDT
Completed Phase 3 Interventional

Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients

NCT04271917
View directory record Official record
Conditions
Pain, Acute
Interventions
cannabidiol, placebo, acetaminophen 500mg and ibuprofen 200mg combo
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 1, 2022 · Synced Jul 23, 2026, 12:44 PM EDT