Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 11, 2026, 3:59 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Pneumothorax, Pleural Effusion
Interventions
No drainage threshold, Drainage <2 mL/kg
Other
Lead sponsor
University of California, Davis
Other
Eligibility
14 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Sacramento, California
Conditions
Thoracotomy, Pain, Postoperative
Interventions
Gabapentin
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Pain, Postoperative, Opioid Use, Perioperative Complication, Heart Diseases
Interventions
bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New Brunswick, New Jersey
Conditions
Pulmonary Disease
Interventions
Progel® Pleural Air Leak Sealant
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
15
States / cities
Jacksonville, Florida • Jupiter, Florida • Miami, Florida + 11 more
Conditions
Tissue Plasminogen Activator
Interventions
early tPA and DNase
Combination Product
Lead sponsor
Prisma Health-Midlands
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Columbia, South Carolina
Conditions
Postoperative Pain
Interventions
TENS Unit
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional Results available

HW006 LATERAL Thoracotomy

NCT02268942
Conditions
Left Sided Heart Failure
Interventions
HeartWare HVAD, Thoracotomy
Device · Procedure
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
19 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
25
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 21 more
Conditions
Pain, Postoperative
Interventions
Ropivacaine infusion
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 4 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Trial Evaluating the Optimal Technique for Chest Tube Removal

NCT00873587
Conditions
Chest Tube Removal
Interventions
Chest tube pull on inspiration, Expiration
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
342 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Pain, Postoperative, Intrathoracic Procedure
Interventions
Atricure's crysoSPHERE probe, Standard of Care
Device · Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Parapneumonic Effusion, Empyema, Pleural, Coagulopathy
Interventions
VATS Decortication, Fibrinolytic Therapy
Procedure · Drug
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Denver, Colorado
Conditions
Pain, Postoperative
Interventions
Gabapentin, Placebo
Drug · Other
Lead sponsor
University of California, Davis
Other
Eligibility
Up to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Sacramento, California
Conditions
Laser Therapy, Post Thoracotomy Pain
Interventions
AvicennaTM class IV laser application
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
25 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
New York, New York
Conditions
Ipsilateral Shoulder Pain
Interventions
Sphenopalatine Ganglion (SPG) Block, lidocaine
Procedure · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
New York, New York
Conditions
Pain, Postoperative, Rib Fracture Multiple
Interventions
Cryoablation of Intercostal Nerves, Standard surgical treatment of patients with multiple rib fractures
Device · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Terminated Phase 3 Interventional

PleuraSeal Pivotal Study (US)

NCT00748124
Conditions
Open Thoracotomy
Interventions
PleuraSeal Sealant System, Standard Tissue Closure Techniques
Device · Procedure
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Bedford, Massachusetts
Conditions
Cardiovascular Disease, Healthcare Associated Infectious Disease, Sternal Superficial Wound Infection, Deep Sternal Infection, Mediastinitis, Thoracotomy, Conduit Harvest or Cannulation Site, Sepsis, Pneumonia
Interventions
There is no intervention. The investigators are interviewing cardiac surgery staff with knowledge of infection prevention.
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Pain
Interventions
Cryoanalgesia, Standard of Care
Device · Drug
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
5
States / cities
Los Angeles, California • Ann Arbor, Michigan • Royal Oak, Michigan + 2 more
Conditions
Healthcare Associated Infectious Disease, Sternal Superficial Wound Infection, Sepsis, Pneumonia, Deep Sternal Infection
Interventions
Not listed
Lead sponsor
Dr. Donald Likosky
Other
Eligibility
18 Years and older
Enrollment
911,754 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed No phase listed Observational

Resuscitative Thoracotomy Practices

NCT05944003
Conditions
Resuscitative Thoracotomy Practices
Interventions
Resuscitative thoracotomies
Procedure
Lead sponsor
Methodist Health System
Other
Eligibility
16 Years to 75 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Congenital Cystic Adenomatoid Malformation
Interventions
Fentanyl
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 6 Months
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma, Osteosarcoma
Interventions
Biospecimen Collection, Computed Tomography, Questionnaire Administration, Thoracoscopy, Thoracotomy
Procedure · Other
Lead sponsor
Children's Oncology Group
Network
Eligibility
Up to 50 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2031
U.S. locations
220
States / cities
Birmingham, Alabama • Anchorage, Alaska • Kingman, Arizona + 142 more
Active, not recruiting No phase listed Observational

Thoracostomy Tube Irrigation: a Multi-Center Trial

NCT05935267
Conditions
Thoracic Trauma
Interventions
thoracic irrigation
Procedure
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Pain Following Thoracotomy Surgery
Interventions
Epidural, Intercostal Bupivicaine (Exparel)
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota