Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Jul 21, 2026, 9:27 AM EDT

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Showing 1–24 of 357 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Death, Sudden, Cardiac, Ventricular Fibrillation, Tachycardia, Atrial Fibrillation, Sick Sinus Syndrome
Interventions
Not listed
Lead sponsor
Medtronic Corporate Technologies and New Ventures
Industry
Eligibility
40 Years and older
Enrollment
1,023 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Cardiac Arrhythmia
Interventions
Proton Particle Therapy
Radiation
Lead sponsor
Konstantinos Siontis
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Tachycardia, Ventricular
Interventions
CyberHeart System
Device
Lead sponsor
Varian, a Siemens Healthineers Company
Industry
Eligibility
60 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Austin, Texas
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias

NCT02413450
Conditions
Inherited Cardiac Arrythmias, Long QT Syndrome (LQTS), Brugada Syndrome (BrS), Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT), Early Repolarization Syndrome (ERS), Arrhythmogenic Cardiomyopathy (AC, ARVD/C), Hypertrophic Cardiomyopathy (HCM), Dilated Cardiomyopathy (DCM), Muscular Dystrophies (Duchenne, Becker, Myotonic Dystrophy), Normal Control Subjects
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2031
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Tachycardia, Atrioventricular Nodal Reentry
Interventions
Freezor® Cardiac Cryoablation Catheter CryoConsole System
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
4
States / cities
Minneapolis, Minnesota • Omaha, Nebraska • New York, New York + 1 more
Conditions
Postural Orthostatic Tachycardia Syndrome
Interventions
Plasma Volume, Exercise Capacity Test - Bicycle, Posture Study
Radiation · Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Subarachnoid Hemorrhage (SAH), Tachycardia
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
1,540 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
New York, New York
Completed Phase 4 Interventional Results available

RIGHT: Rhythm ID Going Head-to-Head Trial

NCT00148954
Conditions
Tachycardia
Interventions
VITALITY 2 Implantable Cardioverter Defibrillator, Medtronic Implantable Cardioverter Defibrillator
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
1,962 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Postural Tachycardia Syndrome
Interventions
Looming task
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
12 Years to 21 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Arrhythmias, Cardiac, Atrial Fibrillation, Atrial Flutter, Bradycardia, Tachycardia
Interventions
Vectorcardiography (VECG)
Device
Lead sponsor
HeartBeam, Inc.
Industry
Eligibility
18 Years and older
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
5
States / cities
Atlanta, Georgia • Tucker, Georgia • New York, New York + 2 more
Conditions
Long QT Syndrome
Interventions
Testosterone, Progesterone, Placebo, Ibutilide
Drug
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older · Male only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Results available

Effect of Exercise in OI

NCT00770484
Conditions
Orthostatic Intolerance, Postural Tachycardia Syndrome
Interventions
Propranolol then Placebo, Placebo then Propranolol
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Atrial Fibrillation
Interventions
Atrial fibrillation ablation
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Long Haul COVID, Postural Orthostatic Tachycardia Syndrome
Interventions
Ivabradine
Drug
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Active, not recruiting Early Phase 1 Interventional

Modafinil and Cognitive Function in POTS

NCT01988883
Conditions
Postural Tachycardia Syndrome
Interventions
Placebo, Modafinil, Propranolol
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Recruiting No phase listed Observational Accepts healthy volunteers

Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS)

NCT06292104
Conditions
Postural Orthostatic Tachycardia Syndrome
Interventions
multimodal diagnostic testing
Diagnostic Test
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
14 Years and older
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Paroxysmal Supraventricular Tachycardia
Interventions
Etripamil, Placebo, Etripamil Test Dose
Drug
Lead sponsor
Milestone Pharmaceuticals Inc.
Other
Eligibility
18 Years and older
Enrollment
1,097 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
54
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Cerritos, California + 44 more
Completed No phase listed Observational

NTX Wireless Patient Monitoring System

NCT00654693
Conditions
Desaturation, Bradycardia, Tachycardia, Hypertension, Hypotension
Interventions
Rapid Response Team
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Completed Not applicable Interventional Results available

Inappropriate Shock Reduction wIth PARAD+ Rhythm DiScrimination

NCT01410552
Conditions
Tachycardia
Interventions
PARADYM DR model 8550; PARADYM CRT model 8750; PARADYM RF DR model 9550; PARADYM RF CRT model 9750; PARADYM RF CRT SonR model 9770
Device
Lead sponsor
MicroPort CRM
Industry
Eligibility
18 Years and older
Enrollment
1,013 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
27
States / cities
Mesa, Arizona • Peoria, Arizona • Phoenix, Arizona + 23 more
Conditions
Tachycardia, Dyspnea, COVID-19
Interventions
Metoprolol Succinate
Drug
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Hackensack, New Jersey
Conditions
Postural Tachycardia Syndrome
Interventions
breathing exercise training
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Completed No phase listed Observational Accepts healthy volunteers

Assessment of Vascular Endothelial Function in Postural Tachycardia Syndrome

NCT01308099
Conditions
Postural Tachycardia Syndrome
Interventions
Blood Pressure and Blood Flow
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
2
States / cities
Nashville, Tennessee
Conditions
Ventricular Tachycardia, Sustained, Ventricular Tachycardia, Monomorphic
Interventions
Ultra Low Temperature Ablation (ULTA)
Device
Lead sponsor
Adagio Medical
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
8
States / cities
Phoenix, Arizona • Long Beach, California • Boston, Massachusetts + 5 more
Completed No phase listed Observational

Novel Cardiac Signal Processing System

NCT04112433
Conditions
Cardiac Arrhythmia
Interventions
PURE EP 2
Device
Lead sponsor
BioSig Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Jacksonville, Florida • Boston, Massachusetts • Austin, Texas