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ClinicalTrials.gov public records Last synced Oct 22, 2026, 10:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–13 of 13 matching trials from the live ClinicalTrials.gov search.

Conditions: Avascular Necrosis of the Talus, Talar Osteochondral Defect of Ankle, Talar Dysfunction
Interventions: Total Talus Replacement (TTR); Device
Lead sponsor: Restor3D; Industry
Eligibility: 22 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2031
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Osteochondral Lesions of Talus
Interventions: ankle arthroscopy with debridement and microfracture of the OLT, Bone Marrow Aspirate injection; Procedure · Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 95 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Chondral Defect, Articular Cartilage Defect
Interventions: autologous cultured chondrocytes on porcine collagen membrane, Bone Marrow Stimulation; Biological · Procedure
Lead sponsor: Vericel Corporation; Industry
Eligibility: 17 Years to 65 Years
Enrollment: 309 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 7
States / cities: Sacramento, California • Washington D.C., District of Columbia • Wichita, Kansas + 4 more

Conditions: Foot Deformities, Acquired, Disorder of Joint of Foot, Fracture of Foot, Deformity of Bone
Interventions: map3; Device
Lead sponsor: RTI Surgical; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Roslyn, New York

Conditions: Ankle Fracture, Calcaneus Fracture, Talus Fracture, Pilon Fracture
Interventions: Manual Therapy Group, Control Group; Other
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 18 Years to 70 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Osteochondral Lesion of Talus
Interventions: Microfracture with Bone Marrow Aspirate Concentrate, Microfracture; Procedure
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Congenital Vertical Talus, Familial Encephalopathy With Neuroserpin Inclusion Bodies, Idiopathic Generalised Epilepsy, Familial Dementia, X-linked Mental Retardation
Interventions: Not listed
Lead sponsor: State University of New York - Upstate Medical University; Other
Eligibility: 6 Months and older
Enrollment: 176 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2015
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: Avascular Necrosis of the Talus
Interventions: Patient Specific Talus Spacer; Device
Lead sponsor: Paragon 28; Industry
Eligibility: 21 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2033
U.S. locations: 5
States / cities: Santa Rosa, California • Fort Wayne, Indiana • Baltimore, Maryland + 2 more

Conditions: Defect of Articular Cartilage, Osteochondral Lesion of Talus, Osteochondritis Dissecans
Interventions: DeNovo NT Natural Tissue Graft; Other
Lead sponsor: Zimmer Orthobiologics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 205 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 8
States / cities: Sacramento, California • Honolulu, Hawaii • Baltimore, Maryland + 5 more

Conditions: Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia, Tibial Plateau Fracture, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Calcaneus Fractures, Talus Fracture, Wound Infection Deep, Wound Infection Post-Traumatic, Wound Dehiscence, Surgical
Interventions: Nitroglycerin Ointment 2%; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Talus, Ankle Arthropathy
Interventions: Total Talus Replacement (TTR), Total Ankle Total Talus Replacement (TATTR), Total Ankle Total Talus Replacement + Subtalar Fusion (TATTR + STJ), Total Talus Replacement + Subtalar Fusion (TTR + STJ); Procedure
Lead sponsor: Restor3D; Industry
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Paducah, Kentucky • Bellevue, Ohio

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