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ClinicalTrials.gov public records Last synced Jun 10, 2026, 1:35 PM EDT

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Showing 1–8 of 8 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Epiphora
Interventions
Sinopsys Lacrimal Stent
Device
Lead sponsor
Sinopsys Surgical
Industry
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
4
States / cities
Stanford, California • Aurora, Colorado • Sarasota, Florida + 1 more
Conditions
Epiphora, Dacryostenosis, Dacryocystitis
Interventions
Proparacaine Hydrochloride ophthalmic solution, USP 0.5%, Balanced salt solution
Drug
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Royal Oak, Michigan
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Bupivacaine Epiphora Trial

NCT03266081
Conditions
Epiphora, Ptosis
Interventions
0.75% bupivacaine
Drug
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
New York, New York
Conditions
Epiphora
Interventions
Botulinum Toxin Type A
Drug
Lead sponsor
Merbs, Shannath, M.D., Ph.D.
Individual
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Epiphora, Dacryocystorhinostomy
Interventions
Slit Stent II, BIKA for DCR
Device
Lead sponsor
Thomas Gardner
Other
Eligibility
22 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed No phase listed Observational

Lacrimal Drainage Resistance Study

NCT01766232
Conditions
Epiphora, Nasolacrimal Duct Obstruction, Canalicular Stenosis, Functional Tear Pump Failure, Ectropion
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Tears; Excess, Eyelid Spasm
Interventions
Botulinum toxin
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Miami, Florida
Conditions
Epiphora, Dacryostenosis, Dacryocystitis
Interventions
Proparacaine Hydrochloride ophthalmic solution, USP 0.5%, Balanced salt solution
Drug
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
New Orleans, Louisiana