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Showing 1–24 of 165 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Teen Sexual Health Clear all
Terminated Not applicable Interventional

Rigorous Evaluation of Yes and Know, a Fully Virtual Sexual Health and Well-Being Intervention for Youth

NCT06581536
View directory record Official record
Conditions
Pregnancy Related, Sexually Transmitted Diseases, Adolescent Behavior
Interventions
Yes and Know curriculum, Nutrition Education for Adolescents
Behavioral
Lead sponsor
ETR Associates
Other
Eligibility
14 Years to 19 Years
Enrollment
449 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Watsonville, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 10, 2026, 4:19 AM EDT
Completed Not applicable Interventional

A Mobile Gaming App to Improve ART Adherence for Youth

NCT03760211
View directory record Official record
Conditions
Medication Adherence, HIV/AIDS
Interventions
Multilevel Gaming Adherence Intervention, Treatment as Usual +
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
15 Years to 30 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
4
States / cities
Atlanta, Georgia • Boston, Massachusetts • Jackson, Mississippi + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Sep 10, 2026, 4:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Community and Physician Perspectives Regarding Male Youth Human Papillomavirus (HPV) Disease and Vaccination

NCT02897232
View directory record Official record
Conditions
Papillomavirus Infections, Health Behavior, Attitude of Health Personnel, Human Papilloma Virus, Male
Interventions
Survey
Other
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years and older
Enrollment
386 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Sep 10, 2026, 4:19 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Multi-level Interventions for STD Prevention Among Adolescents

NCT00146406
View directory record Official record
Conditions
Chlamydia
Interventions
Project Connect
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
11 Years to 20 Years
Enrollment
36,502 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2012 · Synced Sep 10, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PrEP2Prevent An Online PrEP Navigation and Activation Intervention

NCT05281393
View directory record Official record
Conditions
HIV Infections
Interventions
PrEPresent
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
16 Years to 26 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2024 · Synced Sep 10, 2026, 4:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Immunopathogenesis of Chlamydia

NCT00607659
View directory record Official record
Conditions
CHLAMYDIA INFECTIONS
Interventions
No intervention, only observational
Other
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
11 Years to 21 Years · Female only
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2016 · Synced Sep 10, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy Trial of a Brief Parent-Based Adolescent Sexual Health Intervention

NCT02600884
View directory record Official record
Conditions
Increase HPV Vaccination Uptake, Delay Sexual Debut
Interventions
Families Talking Together Plus (FTT+HPV), Brief motivational interviewing (BMI)
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
11 Years and older
Enrollment
1,183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Sep 10, 2026, 4:19 AM EDT
Completed No phase listed Observational

Health, Fitness, and Quality of Life in Adolescent Girls With Turner Syndrome

NCT03181230
View directory record Official record
Conditions
Turner Syndrome, Turner Syndrome Mosaicism, 45, X/46, XX or XY, Turner Syndrome Mosaicism 46,X,I(X)(Q10)/45,X, Turner Syndrome Karyotype 46,X With Abnormal Sex Chromosome , Except I(Xq)
Interventions
No intervention
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 21 Years · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 2, 2021 · Synced Sep 10, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lakota Family Acceptance Project

NCT07326748
View directory record Official record
Conditions
LGBTQ, Racial Disparities, Family Relationships, Minority Stress, Depression, Anxiety, Drug Use, Teen Dating Violence, Sexual Risk Reduction
Interventions
Adapted Lakota Family Acceptance Program
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Pine Ridge, South Dakota • Rapid City, South Dakota
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 10, 2026, 4:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Health Information Technology to Reduce Disparities in Adolescent Health Outcomes: A Pragmatic Trial

NCT04372875
View directory record Official record
Conditions
Sexually Transmitted Diseases
Interventions
SHS-derived CDS
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
15 Years to 21 Years
Enrollment
18,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 10, 2026, 4:19 AM EDT
Terminated Not applicable Interventional

Longitudinal Effects of a Sexual Health Intervention: HEART

NCT04156516
View directory record Official record
Conditions
STD, Adolescent Behavior
Interventions
HEART, HealthyMinds
Behavioral
Lead sponsor
North Carolina State University
Other
Eligibility
Not listed
Enrollment
457 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Sep 10, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PREVENT HPV-Related Cancers - BootCamp Translation

NCT06290206
View directory record Official record
Conditions
HPV Vaccination, Vaccine; Uptake, Vaccination; Series Completion
Interventions
PREVENT - BCT
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 17, 2025 · Synced Sep 10, 2026, 4:19 AM EDT
Completed No phase listed Observational

Evaluating Rewards-Based Adherence and Electronic Medication Monitoring in HIV-Positive Adolescents

NCT01849393
View directory record Official record
Conditions
Human Immunodeficiency Virus (HIV), Acquired Immunodeficiency Syndrome (AIDS)
Interventions
Questionnaire
Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
16 Years to 24 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 15, 2013 · Synced Sep 10, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Youth Mentoring Program

NCT00158353
View directory record Official record
Conditions
Self Concept
Interventions
GirlPOWER! mentoring program, Traditional mentoring
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
10 Years to 13 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Sep 10, 2026, 4:19 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Affect Management Intervention for Early Adolescents Wtih Mental Health Problems

NCT00741975
View directory record Official record
Conditions
HIV Infections
Interventions
Affect Management, General Health Promotion
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
12 Years to 16 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 12, 2012 · Synced Sep 10, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Digital Wellbeing Project

NCT05061966
View directory record Official record
Conditions
Mental Health
Interventions
immi, Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
13 Years to 19 Years
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Sep 10, 2026, 4:19 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Brief Interventions to Increase HPV Vaccine Acceptance in School-based Health Centers

NCT01087164
View directory record Official record
Conditions
Human Papillomavirus Infection
Interventions
Compliance, Message sidedness
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
11 Years to 15 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2014 · Synced Sep 10, 2026, 4:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Parent Toolkit 2.0 (Morehouse Family Health Study)

NCT06579781
View directory record Official record
Conditions
Sexual Behavior, Adolescent Behavior, Sexually Transmitted Diseases, Contraception Behavior, Parent-Child Relations
Interventions
Morehouse Family Health Study's Parent Toolkit 2.0, Morehouse Family Health Study's General Health Guide
Behavioral
Lead sponsor
Child Trends
Other
Eligibility
12 Years to 15 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Cairo, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 10, 2026, 4:19 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Training Community Members to Deliver HIV Prevention Programs to Urban Youth

NCT00859144
View directory record Official record
Conditions
HIV, HIV Infections
Interventions
Be Proud! Be Responsible!, Becoming A Responsible Teen (BART), Reducing the Risk
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
12 Years to 60 Years
Enrollment
901 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2012 · Synced Sep 10, 2026, 4:19 AM EDT
Completed No phase listed Observational

Long-Term Survival With HIV: Psychological and Behavioral Factors Associated With the Transition From Adolescence to Young Adulthood

NCT00026806
View directory record Official record
Conditions
HIV Infection
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 10, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Engaging Seronegative Youth to Optimize HIV Prevention Continuum

NCT03134833
View directory record Official record
Conditions
HIV, Mental Health, Substance Use, STI
Interventions
Automated Messaging & Monitoring, Peer Support, Coaching
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 24 Years
Enrollment
1,478 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
2
States / cities
Los Angeles, California • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 4, 2022 · Synced Sep 10, 2026, 4:19 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Wrap It Up Rigorous Evaluation

NCT06574321
View directory record Official record
Conditions
Pregnancy in Adolescence, Sexually Transmitted Diseases
Interventions
Wrap It Up (WIU)
Behavioral
Lead sponsor
ETR Associates
Other
Eligibility
16 Years to 19 Years
Enrollment
1,120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Scotts Valley, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 10, 2026, 4:19 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Health Education and Relationships Through Theater: An RCT of Promoting Awareness Through Live Movement and Sound for Youth With Autism Spectrum Disorder (PALMS-ASD)

NCT04005547
View directory record Official record
Conditions
Sexual Health, Education, Health
Interventions
Promoting Awareness through Live Movement and Sound for youth with Autism Spectrum Disorder
Behavioral
Lead sponsor
Public Health Management Corporation
Other
Eligibility
14 Years to 19 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 10, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol, Marijuana, and Risky Sex: Group Interventions With Detained Adolescents

NCT01170260
View directory record Official record
Conditions
Risk Reduction Behavior, Health Behavior, Sexual Behavior, Adolescent Behavior, Cannabis
Interventions
INFORMATION-ONLY SEXUAL RISK REDUCTION (INFO-ONLY), SEXUAL PLUS ALCOHOL RISK REDUCTION (SRRI+ETOH), SEXUAL + ALCOHOL + MARIJUANA RISK REDUCTION
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
14 Years to 18 Years
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Sep 10, 2026, 4:19 AM EDT