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ClinicalTrials.gov public records Last synced Oct 2, 2026, 6:37 AM EDT

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Showing 73–96 of 141 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Tetraplegia Clear all
Recruiting Not applicable Interventional

Virtual Peer Coaching in Manual Wheelchair Skills

NCT06295146
View directory record Official record
Conditions
Wheelchair, Paraplegia, Spinal Cord Injury, Tetraplegia/Tetraparesis, Spinal Cord Injuries (SCI)
Interventions
Intervention A: 1-on-1 wheelchair skills training by a peer coach, Intervention B: Training via educational videos
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 2, 2026, 6:37 AM EDT
Enrolling by invitation Not applicable Interventional

mindBEAGLE: Unlocking Functional Communication for Patients With Disorders of Consciousness

NCT06426602
View directory record Official record
Conditions
Disorders of Consciousness
Interventions
mindBEAGLE daily device use
Device
Lead sponsor
Amy Wagner
Other
Eligibility
16 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 2, 2026, 6:37 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Spinal Cord Injury Leg Rehabilitation

NCT01498991
View directory record Official record
Conditions
Spinal Cord Injury, Paraplegia, Quadriplegia, Tetraplegia
Interventions
AMES Treatment
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Atlanta, Georgia • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 24, 2019 · Synced Oct 2, 2026, 6:37 AM EDT
Recruiting Not applicable Interventional

Cortical Recording and Stimulating Array Brain-Machine Interface

NCT01894802
View directory record Official record
Conditions
Tetraplegia, Spinal Cord Injury, Brainstem Stroke, Brachial Plexus Injury, Above Elbow Amputation
Interventions
Implantation of CRS Arrays
Device
Lead sponsor
Michael Boninger
Other
Eligibility
22 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2029
U.S. locations
2
States / cities
Chicago, Illinois • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 2, 2026, 6:37 AM EDT
Completed Phase 1Phase 2 Interventional

A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries

NCT00500812
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Cethrin
Drug
Lead sponsor
Vertex Pharmaceuticals Incorporated
Industry
Eligibility
16 Years to 70 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
5
States / cities
Phoenix, Arizona • Cincinnati, Ohio • Philadelphia, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Oct 2, 2026, 6:37 AM EDT
Completed Not applicable Interventional Results available

Providing Brain Control of Extracorporeal Devices to Patients With Quadriplegia

NCT01849822
View directory record Official record
Conditions
Tetraplegia
Interventions
Neural Prosthetic System
Device
Lead sponsor
Richard A. Andersen, PhD
Other
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
3
States / cities
Downey, California • Los Angeles, California • Pasadena, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2021 · Synced Oct 2, 2026, 6:37 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Spinal Cord Associative Plasticity Study

NCT05163639
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
Interventions
Non-invasive pairing of cortical and spinal stimulation, Intraoperative pairing of cortical and spinal stimulation, Non-invasive repeated pairing of cortical and spinal stimulation (SCAP), Intraoperative repeated pairing of cortical and spinal stimulation (SCAP), Intraoperative repeated pairing of cortical and spinal stimulation (SCAP) at or below myelopathic region
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
3
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 2, 2026, 6:37 AM EDT
Recruiting No phase listed Observational

Nerve Transfers Plus Electrical Stimulation to Improve Hand Function in Cervical Spinal Cord Injury

NCT06541041
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Cervical Spinal Cord Paralysis, Tetraplegia, Tetraplegia/Tetraparesis, Tetraplegic Spinal Paralysis
Interventions
Brief intraoperative electrical stimulation, Temporary Postoperative Peripheral Nerve Stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 2, 2026, 6:37 AM EDT
Completed Not applicable Interventional

Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function

NCT04777149
View directory record Official record
Conditions
Spinal Cord Injuries, Tetraplegia, Cervical Spinal Cord Injury
Interventions
transcranial Random Noise Stimulation (tRNS), transcranial Direct Current Stimulation (tDCS), sham-stimulation
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 26, 2022 · Synced Oct 2, 2026, 6:37 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Body Temperature in Persons With Tetraplegia When Exposed to Cold

NCT01822535
View directory record Official record
Conditions
Tetraplegia, Hypothermia, Mild Cognitive Impairment
Interventions
Midodrine hydrochloride
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 68 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 4, 2016 · Synced Oct 2, 2026, 6:37 AM EDT
Not listed Phase 1 Interventional

Acute and Chronic Effects of Inhaled Steroids on Pulmonary Function in Persons With Spinal Cord Injury

NCT01353599
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Mometasone furoate
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
2
States / cities
West Orange, New Jersey • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 23, 2015 · Synced Oct 2, 2026, 6:37 AM EDT
Completed Not applicable Interventional

Mindfulness Meditation for Subjects With Severe Speech and Physical Impairments

NCT01964664
View directory record Official record
Conditions
Physical Impairments, Cerebral Palsy, Cerebral Ataxia, locked-in Syndrome
Interventions
Mindfulness Meditation Training, Audio Group
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Portland Metropolitan Area, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 2, 2026, 6:37 AM EDT
Completed Phase 1 Interventional

The Safety of ahSC in Chronic SCI With Rehabilitation

NCT02354625
View directory record Official record
Conditions
Spinal Cord Injury, Paraplegia, Quadriplegia, Tetraplegia
Interventions
Autologous human Schwann cells
Biological
Lead sponsor
W. Dalton Dietrich
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 2, 2026, 6:37 AM EDT
Withdrawn No phase listed Observational

Nerve Transfers to Restore Hand Function in Spinal Cord Injury

NCT02861612
View directory record Official record
Conditions
Quadriplegia, Spinal Cord Diseases, Spinal Cord Injuries
Interventions
Nerve Transfer Surgery
Procedure
Lead sponsor
Ottawa Hospital Research Institute
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Oct 2, 2026, 6:37 AM EDT
Completed Not applicable Interventional

Conditioning Neural Circuits to Improve Upper Extremity Function

NCT02611375
View directory record Official record
Conditions
Spinal Cord Injury, Tetraplegia
Interventions
transcranial direct current stimulation, peripheral nerve somatosensory stimulation, sham transcranial direct current stimulation
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Oct 2, 2026, 6:37 AM EDT
Recruiting Phase 1Phase 2 Interventional

Psilocybin to Treat Depression in Spinal Cord Injury

NCT07251491
View directory record Official record
Conditions
Spinal Cord Injury, Depression - Major Depressive Disorder, Veteran
Interventions
Psilocybin (Usona Institute)
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
22 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 2, 2026, 6:37 AM EDT
Completed No phase listed Observational

Follow up Study of Diaphragm Pacing for Patients With High Tetraplegia

NCT01815554
View directory record Official record
Conditions
Tetraplegia, Spinal Cord Injury
Interventions
Not listed
Lead sponsor
Craig Hospital
Other
Eligibility
Not listed
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Oct 2, 2026, 6:37 AM EDT
Withdrawn Not applicable Interventional

Virtual Reality and Spinal Stimulation to Improve Arm Function

NCT05065437
View directory record Official record
Conditions
Tetraplegia
Interventions
Active (Virtual reality and spinal stimulation)
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 1, 2022 · Synced Oct 2, 2026, 6:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of mindBEAGLE in Disorders of Consciousness or Locked-In Syndrome

NCT02772302
View directory record Official record
Conditions
Consciousness Disorders, Locked-In Syndrome
Interventions
mindBEAGLE EEG-based brain-computer interface
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Oct 2, 2026, 6:37 AM EDT
Completed Not applicable Interventional

Effects of Exercise in People With Tetraplegia

NCT01202019
View directory record Official record
Conditions
Spinal Cord Injury, Tetraplegia
Interventions
Circuit Resistance Training (CRT)
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 55 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 22, 2014 · Synced Oct 2, 2026, 6:37 AM EDT
Active, not recruiting Not applicable Interventional

COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis

NCT05035823
View directory record Official record
Conditions
Neurologic Disorder, Paralysis, Paralysis; Stroke, Amyotrophic Lateral Sclerosis, Muscular Dystrophies, Spinal Cord Injuries, Stroke, Lacunar, Stroke Brainstem, Cervical Spinal Cord Injury, Spinal Muscular Atrophy, Tetraplegic; Paralysis, Quadriplegia/Tetraplegia
Interventions
Motor Neuroprosthesis (MNP)
Device
Lead sponsor
Synchron Medical, Inc.
Industry
Eligibility
21 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
3
States / cities
Buffalo, New York • New York, New York • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 2, 2026, 6:37 AM EDT
Completed No phase listed Observational

Sleep Disordered Breathing

NCT01467856
View directory record Official record
Conditions
Sleep Disordered Breathing, Tetraplegia
Interventions
PAP Device Procedure
Procedure
Lead sponsor
Mark S. Nash, Ph.D., FACSM
Other
Eligibility
18 Years to 65 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 17, 2017 · Synced Oct 2, 2026, 6:37 AM EDT
Not listed Not applicable Interventional

Telehealth Implementation of Brain-Computer Interface

NCT05951556
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Stroke
Interventions
Use of BCI
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
16 Years to 100 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Oct 2, 2026, 6:37 AM EDT
Recruiting Not applicable Interventional

Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia

NCT07225582
View directory record Official record
Conditions
Spinal Cord Injury Cervical, Spinal Cord Injuries (Complete and Incomplete)
Interventions
Brain Computer Interface (BCI) - Functional Electrical Stimulation (FES) system
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
22 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Oct 2, 2026, 6:37 AM EDT