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ClinicalTrials.gov public records Last synced Oct 30, 2026, 11:13 AM EDT

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Showing 1–24 of 47 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Thermal Burns Clear all
Withdrawn Phase 2 Interventional

Vitamin C for Severe Thermal Injuries

NCT01587261
View directory record Official record
Conditions
Severe Thermal Injury, Greater Than 20% TBSA
Interventions
Vitamin C, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Oct 30, 2026, 11:13 AM EDT
Not listed Not applicable Interventional

Safety Study of a Novel Wearable Phototherapy System for the Management of Acute Burn Wounds

NCT03948360
View directory record Official record
Conditions
Burn Wound
Interventions
Low-Irradiance Monochromatic Biostimulation (LIMB) Device, Standard of Care
Device · Other
Lead sponsor
Rogers Sciences Inc.
Industry
Eligibility
Up to 21 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2019 · Synced Oct 30, 2026, 11:13 AM EDT
Completed No phase listed Observational

Chronology of Occult and Gross Coagulopathy in Burn Patients

NCT01638481
View directory record Official record
Conditions
Thermal Burns
Interventions
Not listed
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 16, 2022 · Synced Oct 30, 2026, 11:13 AM EDT
Completed No phase listed Observational

Feasibility of Obtaining ADRCs From Discarded Thermal Burn Eschar Tissue Using Investigational Celution® System

NCT02362386
View directory record Official record
Conditions
Thermal Burn
Interventions
Celution Device
Device
Lead sponsor
Cytori Therapeutics
Industry
Eligibility
Up to 80 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
4
States / cities
Phoenix, Arizona • San Diego, California • Galveston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2016 · Synced Oct 30, 2026, 11:13 AM EDT
Not listed Not applicable Interventional

Evaluation of the Effectiveness of PermeaDerm® (PD) as Compared to Mepilex Ag®

NCT05084183
View directory record Official record
Conditions
Thermal Burn
Interventions
PermeaDerm®, Mepilex Ag
Device
Lead sponsor
Stedical Scientific, Inc.
Industry
Eligibility
Up to 75 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced Oct 30, 2026, 11:13 AM EDT
Withdrawn Phase 4 Interventional

A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn Patients

NCT02336308
View directory record Official record
Conditions
Thermal Hyperalgesia, Anxiety, Pain
Interventions
Ketamine, Placebo, Normal Saline
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 26, 2015 · Synced Oct 30, 2026, 11:13 AM EDT
Completed Phase 3 Interventional Results available

StrataGraft® Skin Tissue Expanded Access at Specific Study Sites ( StrataCAT )

NCT04123548
View directory record Official record
Conditions
Deep Partial-thickness Burn
Interventions
StrataGraft skin tissue
Biological
Lead sponsor
Stratatech, a Mallinckrodt Company
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
10
States / cities
Orange, California • Washington D.C., District of Columbia • Gainesville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 9, 2023 · Synced Oct 30, 2026, 11:13 AM EDT
Completed Phase 3 Interventional Results available

A Study to Evaluate the Efficacy and Safety of NexoBrid in Subjects With Thermal Burns

NCT02148705
View directory record Official record
Conditions
Thermal Burns
Interventions
NexoBrid, Standard of Care (SOC), Gel Vehicle
Drug · Procedure
Lead sponsor
MediWound Ltd
Industry
Eligibility
18 Years to 77 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
18
States / cities
Mobile, Alabama • Phoenix, Arizona • Aurora, Colorado + 15 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced Oct 30, 2026, 11:13 AM EDT
Recruiting Phase 3 Interventional

Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Burn Wounds as an Alternative to Autografting

NCT06223269
View directory record Official record
Conditions
Burns Degree Third, Burn (Disorder), Burn Degree Second, Thermal Burn, Wound Heal
Interventions
Skin Xenotransplant, Autograft(ing)
Drug · Procedure
Lead sponsor
XenoTherapeutics, Inc.
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Phoenix, Arizona • Augusta, Georgia • Portland, Maine + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Oct 30, 2026, 11:13 AM EDT
Completed Not applicable Interventional

The Effects of Viscoelastometry Guided Resuscitation During Burn Excision on Post Resuscitation Infections

NCT03730415
View directory record Official record
Conditions
Burns
Interventions
Viscoelastic (VE) Guided Transfusion
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Oct 30, 2026, 11:13 AM EDT
Suspended Phase 3 Interventional

VItamin C in Thermal injuRY: The VICToRY Trial

NCT04138394
View directory record Official record
Conditions
Shock, Thermal Burn
Interventions
Ascorbic Acid, placebo
Drug
Lead sponsor
Clinical Evaluation Research Unit at Kingston General Hospital
Other
Eligibility
18 Years and older
Enrollment
666 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
10
States / cities
Phoenix, Arizona • Bridgeport, Connecticut • Washington D.C., District of Columbia + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 30, 2026, 11:13 AM EDT
Completed Not applicable Interventional

Study of Low Adherent Dressing Versus the Standard of Care for the Management of Skin Grafts Over Thermal Burns

NCT01654094
View directory record Official record
Conditions
Burns, Skin Burn Requiring Skin Graft
Interventions
P6 Low Adherent Dressing, Standard of Care (SOC)
Device · Other
Lead sponsor
Milliken Healthcare Products, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
4
States / cities
Gainesville, Florida • Chapel Hill, North Carolina • Winston-Salem, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2017 · Synced Oct 30, 2026, 11:13 AM EDT
Recruiting Phase 2 Interventional

Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

NCT01297400
View directory record Official record
Conditions
Burns
Interventions
Investigational Drug, MW-III, Silvadene® Cream 1% [Silver Sulfadiazine]
Drug
Lead sponsor
Skingenix, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Phoenix, Arizona • Sacramento, California • Washington D.C., District of Columbia + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 30, 2026, 11:13 AM EDT
Active, not recruiting Not applicable Interventional

STAT: Standard Therapy Plus Active Therapy

NCT04368117
View directory record Official record
Conditions
Burn Injury, Physical Injury, Thermal Burn
Interventions
Physical Therapy
Behavioral
Lead sponsor
American Burn Association
Other
Eligibility
18 Years to 65 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
7
States / cities
Phoenix, Arizona • Sacramento, California • Maywood, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 30, 2026, 11:13 AM EDT
Terminated No phase listed Observational

Evaluating MMPs in Burns

NCT03148977
View directory record Official record
Conditions
Burns, Thermal Burn, Thermal Injury
Interventions
Graft
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 98 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 26, 2021 · Synced Oct 30, 2026, 11:13 AM EDT
Not listed Phase 2 Interventional

Efficacy of R-Pdf/Gbb in Healing Wounds Caused by Third Degree Thermal and Electrical Burns

NCT00812513
View directory record Official record
Conditions
Burns, Electric Burns
Interventions
R-Pdf/Gbb 0.01% gel
Drug
Lead sponsor
American Scitech International
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Livingston, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 20, 2011 · Synced Oct 30, 2026, 11:13 AM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Pilot Studies Testing the Use of Oral Amitriptyline in Reducing Localized Burn Injury-induced Microvesicle Particle Release

NCT07640061
View directory record Official record
Conditions
Microvesicle Particles, Thermal Burn
Interventions
Amitriptyline, Placebo
Drug
Lead sponsor
Wright State University
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2033
U.S. locations
1
States / cities
Fairborn, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 30, 2026, 11:13 AM EDT
Not yet recruiting No phase listed Observational

Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Sepsis Digital Twin. Group 1

NCT07249762
View directory record Official record
Conditions
Sepsis, Burn Injury, Wound Healing, Critical Illness, Multiple Organ Dysfunction Syndrome
Interventions
Observational Cohort (No Intervention)
Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Tampa, Florida • Atlanta, Georgia • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 30, 2026, 11:13 AM EDT
Not listed Phase 1 Interventional

Applying Platelet Rich Plasma (PRP) Gel to Acute Deep Partial Thickness Thermal Injuries

NCT02169362
View directory record Official record
Conditions
Acute Deep Partial Thickness Thermal Burns
Interventions
Autologous Platelet Rich Plasma (PRP) Gel (Magellan® Bio-Bandage™)
Device
Lead sponsor
Arteriocyte, Inc.
Industry
Eligibility
18 Years to 86 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
8
States / cities
Phoenix, Arizona • Sacramento, California • Washington D.C., District of Columbia + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 30, 2026, 11:13 AM EDT
Recruiting Not applicable Interventional

VR-PMR for Post-Burn Symptoms

NCT07317271
View directory record Official record
Conditions
Burn, Chronic Pain Following Thermal Burn Injury, Non-Pharmacological Interventions, Virtual Reality, Sleep Disturbance, Anxiety, Depressive Symptoms, Fatigue Symptom, Pruritus, Burn Injury, Progressive Muscle Relaxation
Interventions
Virtual Reality-Enhanced Progressive Muscle Relaxation, Standard Progressive Muscle Relaxation
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 30, 2026, 11:13 AM EDT
Terminated Not applicable Interventional Results available

Single-Stage Integra Reconstruction in Burns

NCT03077087
View directory record Official record
Conditions
Thermal Burn
Interventions
thin Integra® (125 cm2)
Device
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 125 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 14, 2023 · Synced Oct 30, 2026, 11:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study in the Use of Virtual Reality as an Adjunct to Pain Control in Burn Patients

NCT00591448
View directory record Official record
Conditions
Burn
Interventions
Virtual Reality (VR)
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
6 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 17, 2012 · Synced Oct 30, 2026, 11:13 AM EDT
Withdrawn Phase 2 Interventional

Pilot Study to Compare Topical Voriconazole to Placebo as a Pain Reducing Agent

NCT02689713
View directory record Official record
Conditions
Pain, Thermal Injury, Burns, Hyperalgesia
Interventions
Voriconazole (topical), Topical Sterile Water Placebo Group
Drug
Lead sponsor
Kenneth Hargreaves
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 17, 2018 · Synced Oct 30, 2026, 11:13 AM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Pilot Studies Blocking Injury-Induced MVP Release in Skin Using Topical Amitriptyline

NCT07716722
View directory record Official record
Conditions
Thermal Burn, Amitriptyline
Interventions
Amitriptyline, Placebo
Drug · Other
Lead sponsor
Wright State University
Other
Eligibility
18 Years to 64 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Fairborn, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 30, 2026, 11:13 AM EDT