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ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:11 PM EDT

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Showing 121–144 of 231 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Thoracic Surgical Procedures Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Walking for Recovery From Surgery in Improving Quality of Life in Older Adults With Lung or Gastrointestinal Cancer and Their Family Caregivers

NCT03267524
View directory record Official record
Conditions
Adult Liver Carcinoma, Caregiver, Colorectal Carcinoma, Lung Carcinoma, Malignant Digestive System Neoplasm, Pancreatic Carcinoma
Interventions
Exercise Intervention, Quality-of-Life Assessment, Survey Administration
Behavioral · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
21 Years and older
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Oct 20, 2026, 6:11 PM EDT
Active, not recruiting Not applicable Interventional

A Study of ETHIZIA Versus SURGICEL Original in Controlling Soft Tissue Bleeding During Open Surgery

NCT06664788
View directory record Official record
Conditions
Hemostasis, Hemostatic Techniques
Interventions
ETHIZIA, SURGICEL Original
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
22 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
6
States / cities
Los Angeles, California • St Louis, Missouri • Pennington, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 20, 2026, 6:11 PM EDT
Completed Phase 4 Interventional

Evaluation of Surgical Treatment on Pain and Disability for Chronic, Non-healing Rib Fracture

NCT00774618
View directory record Official record
Conditions
Rib Fracture
Interventions
Resection with or without plate fixation
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 22, 2013 · Synced Oct 20, 2026, 6:11 PM EDT
Not listed Phase 2 Interventional

Exclusion of the Left Atrial Appendage (LAA) With the LAAx, Inc. TigerPaw System

NCT00962702
View directory record Official record
Conditions
Stroke
Interventions
LAAx TigerPaw System
Device
Lead sponsor
LAAx, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 20, 2009 · Synced Oct 20, 2026, 6:11 PM EDT
Completed Phase 2 Interventional Results available

Percutaneous Image Guided Video-Assisted Thoracic Surgery (VATS) Resection of Lung Lesions

NCT01847209
View directory record Official record
Conditions
Lung Cancer
Interventions
Video-Assisted Thoracic Surgery (VATS) wedge resection
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 20, 2026, 6:11 PM EDT
Not listed Not applicable Interventional

A Randomized Control Trial of ZEPHYRx Gamified Incentive Spirometry Compared to Traditional Spirometry

NCT04429009
View directory record Official record
Conditions
Thoracic Surgery, Respiratory Therapy
Interventions
ZEPHYRx Respiratory Therapy (RT) System, Standard Incentive Spirometer
Device
Lead sponsor
My Music Machines Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Oct 20, 2026, 6:11 PM EDT
Completed Phase 2 Interventional Results available

Fixed Versus Weight-Based Enoxaparin Dosing in Thoracic Surgery Patients

NCT03251963
View directory record Official record
Conditions
Venous Thromboembolism, Deep Venous Thrombosis, Surgery
Interventions
Fixed Dose Enoxaparin, Variable Dose Enoxaparin
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 20, 2026, 6:11 PM EDT
Terminated No phase listed Observational

AKI in Thoracic and Abdominal Surgery

NCT02553174
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 2, 2018 · Synced Oct 20, 2026, 6:11 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Efficacy Between Serratus Plane Block And Local Infiltration In Vats

NCT03642457
View directory record Official record
Conditions
Lung Cancer
Interventions
Bupivacaine, Bupivacaine liposome
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 75 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2020 · Synced Oct 20, 2026, 6:11 PM EDT
Terminated Phase 4 Interventional Results available

Post-Operative Urinary Retention (POUR) in Thoracic Surgery Patients Receiving Prophylactic Tamsulosin

NCT04994431
View directory record Official record
Conditions
Thoracic Diseases, Urinary Retention
Interventions
Tamsulosin Hydrochloride
Drug
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
60 Years and older · Male only
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Oct 20, 2026, 6:11 PM EDT
Recruiting Phase 3 Interventional

Erector Spinae Versus Intercostal Nerve Blocks With Liposomal Bupivacaine for Analgesia in Thoracic Surgery

NCT06810375
View directory record Official record
Conditions
Lung Cancers
Interventions
Erector Spinae (ESP) Block with Bupivacaine (Marcaine®), Intercostal nerve block
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 90 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 20, 2026, 6:11 PM EDT
Completed No phase listed Observational

Dysphagia in Thoracic Surgical Patients

NCT04487028
View directory record Official record
Conditions
Thoracic Diseases
Interventions
Fiberoptic Endoscopic Evaluation of Swallowing
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
3
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 24, 2021 · Synced Oct 20, 2026, 6:11 PM EDT
Active, not recruiting Phase 3 Interventional Results available

A Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Removal and Adjuvant Treatment With Nivolumab or Placebo for Participants With Surgically Removable Early Stage Non-small Cell Lung Cancer

NCT04025879
View directory record Official record
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
Nivolumab, Carboplatin, Cisplatin, Paclitaxel, Pemetrexed, Placebo, Docetaxel
Biological · Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years and older
Enrollment
461 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
15
States / cities
Tampa, Florida • Atlanta, Georgia • Augusta, Georgia + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 20, 2026, 6:11 PM EDT
Completed Not applicable Interventional

Fentanyl With or Without Bupivacaine in Reducing Pain in Patients Undergoing Video-Assisted Chest Surgery

NCT00538499
View directory record Official record
Conditions
Pain, Perioperative/Postoperative Complications
Interventions
Fentanyl citrate, Bupivacaine hydrocloride, videothoracoscopy
Drug · Procedure
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
Up to 120 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced Oct 20, 2026, 6:11 PM EDT
Completed Not applicable Interventional Results available

Pilot Testing a Home-Based Rehabilitation Intervention Designed to Improve Outcomes of Frail Veterans Following Cardiothoracic Surgery

NCT03299101
View directory record Official record
Conditions
Coronary Artery Bypass Graft, Non-cardiac Thoracic Surgery, Frailty
Interventions
Prehabilitation
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2021 · Synced Oct 20, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Improving Thoracic Surgical Care Using Electronic Patient-Reported Outcomes (ePROS)

NCT06075316
View directory record Official record
Conditions
Thoracic
Interventions
Symptom monitoring
Other
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 99 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 20, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Auricular Acupressure in Prehabilitation

NCT06516198
View directory record Official record
Conditions
Frailty, Thoracic, Prehabilitation, Lung Surgery, Wedge Resection, Segmentectomy, Lobectomy, Pneumonectomy; Status
Interventions
Auricular Acupressure
Other
Lead sponsor
University of Chicago
Other
Eligibility
50 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 20, 2026, 6:11 PM EDT
Completed No phase listed Observational

Single Site Thoracic Surgery for Pediatric Pneumothorax

NCT05034640
View directory record Official record
Conditions
Pediatric Disorder, Pneumothorax, Spontaneous, Thoracic Diseases, Thoracic Surgery
Interventions
Conventional multiport thoracoscopic surgery, Single port site thoracoscopic surgery
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
Up to 19 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Oct 20, 2026, 6:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

VivaSight Double Lumen Tube for Single Lung Ventilation

NCT03690284
View directory record Official record
Conditions
Double Lumen Endotracheal Tube, Single Lung Ventilation
Interventions
Conventional Double Lumen Tube, VivaSight Double Lumen Tube
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2022 · Synced Oct 20, 2026, 6:11 PM EDT
Completed No phase listed Observational

Percutaneous Localization: Open-label Registry of Thoracic Surgery

NCT04066699
View directory record Official record
Conditions
Lung Lesion(s) Requiring Evaluation, Pulmonary Metastasis, Pulmonary Nodule, Solitary, Peripheral Lung Lesions
Interventions
Percutaneous localization of suspicious lung lesion(s) using electromagnetic navigation and tools.
Procedure
Lead sponsor
Veran Medical Technologies
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
5
States / cities
Lone Tree, Colorado • Bangor, Maine • Poughkeepsie, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 17, 2024 · Synced Oct 20, 2026, 6:11 PM EDT
Withdrawn Phase 4 Interventional

The Effect of Decreasing the Inspired Oxygen Concentration on Post-Operative Oxygenation After Primary Lobectomy

NCT02509182
View directory record Official record
Conditions
Hyperoxia
Interventions
60% oxygen, 100% oxygen
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 12, 2018 · Synced Oct 20, 2026, 6:11 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Erector Spinae Plane vs. Paravertebral Nerve Block for Thoracic Surgery

NCT03758261
View directory record Official record
Conditions
Thoracic Surgical Procedures
Interventions
Paravertebral nerve block, Erector Spinae nerve block
Drug
Lead sponsor
Charles Luke
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 3, 2023 · Synced Oct 20, 2026, 6:11 PM EDT
Terminated Phase 2 Interventional Results available

Trial of Andexanet in Patients Receiving an Oral FXa Inhibitor Who Require Urgent Surgery

NCT04233073
View directory record Official record
Conditions
Surgery
Interventions
andexanet alfa
Drug
Lead sponsor
Alexion Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 84 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
20
States / cities
Phoenix, Arizona • Tucson, Arizona • Long Beach, California + 15 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 20, 2026, 6:11 PM EDT
Completed Phase 4 Interventional Results available

Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures

NCT03305666
View directory record Official record
Conditions
Drug Effect, Rib Fractures, Rib Trauma, Surgical Procedure, Unspecified, Pain; Catheter (Other), Nerve Pain, Local Infiltration, Anesthesia, Local, Intercostal Rib, Opioid Dependence, Chest Injury Trauma, Pneumonia
Interventions
Liposomal bupivacaine injection, Bupivacaine indwelling catheter
Drug
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Oct 20, 2026, 6:11 PM EDT