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ClinicalTrials.gov public records Last synced Oct 25, 2026, 7:55 AM EDT

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Showing 121–144 of 194 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Thoracic Trauma Clear all
Completed Not applicable Interventional

Thoracic Blocks Versus Thoracic Epidural and Patient Controlled Anesthesia in Traumatic Rib Fracture Patients

NCT01599403
View directory record Official record
Conditions
Traumatic Rib Fracture
Interventions
Paravertebral Block, Intercostal Nerve Block, Epidural Block
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2017 · Synced Oct 25, 2026, 7:55 AM EDT
Completed Not applicable Interventional

Thoraflex™ Hybrid IDE Study

NCT02724072
View directory record Official record
Conditions
Aortic Aneurysm, Aortic Dissection, Aortic Rupture
Interventions
Thoraflex™ Hybrid Device
Device
Lead sponsor
Bolton Medical
Industry
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
12
States / cities
Palo Alto, California • Atlanta, Georgia • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Oct 25, 2026, 7:55 AM EDT
Terminated Phase 4 Interventional Results available

Continuous Erector Spinae Plane Blocks for Rib Fractures

NCT04558281
View directory record Official record
Conditions
Rib Fractures, Trauma, Anesthesia, Anesthesia, Local
Interventions
Active ropivacaine 0.3% erector spinae plane perineural administration, Placebo erector spinae plane perineural administration
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 12, 2023 · Synced Oct 25, 2026, 7:55 AM EDT
Completed Not applicable Interventional

Suction Versus Water Seal for Initial Treatment of Traumatic Pneumothorax Trial

NCT06688734
View directory record Official record
Conditions
Pneumothorax, Trauma
Interventions
Inital water seal, Initial suction
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 25, 2026, 7:55 AM EDT
Recruiting Early Phase 1 Interventional

Post Operative Urinary Retention (POUR) Following Thoracic Oncological Surgery

NCT05657990
View directory record Official record
Conditions
Urinary Retention
Interventions
Tamsulosin
Drug
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
55 Years and older · Male only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Brick, New Jersey • Manahawkin, New Jersey • Neptune City, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 25, 2026, 7:55 AM EDT
Completed Not applicable Interventional

Translating ECHOS2 Into an mHealth Platform

NCT05923242
View directory record Official record
Conditions
Childhood Cancer, Cardiac Toxicity, Pediatric Cancer
Interventions
Computerized Intervention Authoring Software (CIAS)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Oct 25, 2026, 7:55 AM EDT
Completed Not applicable Interventional Results available

EZ-blocker Versus Left Sided Double Lumen Tube in Adult Patients for Thoracic Surgery

NCT03403192
View directory record Official record
Conditions
Thoracic Injuries
Interventions
EZ-Blocker, DLT
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 25, 2026, 7:55 AM EDT
Not listed Phase 2 Interventional

Amifostine to Prevent Side Effects in Patients Who Are Receiving Chemotherapy and Radiation Therapy for Limited-Stage Small Cell Lung Cancer

NCT00003583
View directory record Official record
Conditions
Drug/Agent Toxicity by Tissue/Organ, Lung Cancer, Radiation Toxicity
Interventions
amifostine trihydrate, cisplatin, etoposide, radiation therapy
Drug · Radiation
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1997
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 4, 2013 · Synced Oct 25, 2026, 7:55 AM EDT
Completed No phase listed Observational

Pharmacologic Impact on Sedation Assessments

NCT01105663
View directory record Official record
Conditions
Pediatric Acute Lung Injury
Interventions
Pharmacokinetic Sampling and pharmacogenetic analysis
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Year to 17 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 27, 2017 · Synced Oct 25, 2026, 7:55 AM EDT
Active, not recruiting No phase listed Observational

Imaging and Blood-Based Biomarkers for the Evaluation of Early Signs of Myocardial Injury After Thoracic Radiation Therapy

NCT05717998
View directory record Official record
Conditions
Lung Non-Small Cell Carcinoma, GastroEsophageal Cancer, Esophagus Cancer
Interventions
Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging of the Heart, Positron Emission Tomography
Procedure
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 25, 2026, 7:55 AM EDT
Terminated Not applicable Interventional

Effect of Bracing Versus No Bracing in Stable Thoracolumbar Compression and Burst Fractures

NCT03952182
View directory record Official record
Conditions
Thoracic Fracture, Lumbar Fracture, Compression Fracture of Thoracic Vertebral Body, Compression Fracture of Lumbar Spine, Burst Fracture of Thoracic Vertebra, Burst Fracture of Lumbar Vertebra
Interventions
Spinal Orthosis (LSO, TLSO), No orthosis
Other
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Oct 25, 2026, 7:55 AM EDT
Withdrawn Phase 1 Interventional

CLBS119 for Repair of COVID-19 Induced Pulmonary Damage

NCT04522817
View directory record Official record
Conditions
Covid-19
Interventions
CLBS119
Biological
Lead sponsor
Lisata Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Oct 25, 2026, 7:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-Interruptive Alerts for Improving Use of Clinical Decision Rules

NCT04702308
View directory record Official record
Conditions
Pulmonary Embolism, Deep Vein Thrombosis, Minor Head Injury, Chest Pain, Neck Trauma
Interventions
Clinical Decision Rule Alerts
Other
Lead sponsor
University of Utah
Other
Eligibility
16 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 25, 2026, 7:55 AM EDT
Completed Not applicable Interventional Results available

Zenith® Dissection Clinical Trial

NCT01568320
View directory record Official record
Conditions
Aortic Dissection
Interventions
Endovascular Treatment (Zenith)
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
23
States / cities
Los Angeles, California • Gainesville, Florida • Tampa, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Oct 25, 2026, 7:55 AM EDT
Terminated Early Phase 1 Interventional

Hyperpolarized Carbon 13-Based Metabolic Imaging to Detect Radiation-Induced Cardiotoxicity

NCT04044872
View directory record Official record
Conditions
Thoracic Cancer, Left Sided Breast Cancer
Interventions
[1-13C]pyruvate along with MRI imaging
Diagnostic Test
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 25, 2026, 7:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Multi-center:The Small (14F) Percutaneous Catheter vs. Large (28-40F) Open Chest Tube for Traumatic Hemothorax (P-CAT)

NCT03546764
View directory record Official record
Conditions
The Efficacy of Percutaneous Catheter vs. Open Chest Tube, Traumatic Hemothorax
Interventions
Percutaneous catheter
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
4
States / cities
Tucson, Arizona • Atlanta, Georgia • Omaha, Nebraska + 1 more
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Oct 25, 2026, 7:55 AM EDT
Recruiting Not applicable Interventional

Incentive Spirometry to Improve Outcomes in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy

NCT06688422
View directory record Official record
Conditions
Lung Cancer, Pneumonitis, Radiation-Induced Lung Injury, Immunotherapy-Induced Pneumonitis, Non-Small-Cell Lung Cancer (NSCLC)
Interventions
incentive spirometry
Device
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 25, 2026, 7:55 AM EDT
Recruiting Phase 2 Interventional

Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury

NCT04485286
View directory record Official record
Conditions
Lung Cancer, Radiation Fibrosis, Radiation Induced Lung Injury, Pancreas Cancer
Interventions
[68Ga]CBP8
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 25, 2026, 7:55 AM EDT
Not listed No phase listed Observational

Point-of-Care Ultrasound for Pediatric Thoracic Trauma: A Multi-Institutional Trial

NCT05025150
View directory record Official record
Conditions
Trauma Chest, Pediatric ALL
Interventions
Not listed
Lead sponsor
Sutter Health
Other
Eligibility
0 Years to 21 Years
Enrollment
1,020 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Oct 25, 2026, 7:55 AM EDT
Completed No phase listed Observational

Effects of Using E-Cigarettes on Lungs in People With HIV (HBS Ancillary)

NCT04794543
View directory record Official record
Conditions
Hiv, Lung Injury
Interventions
Not listed
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Baton Rouge, Louisiana • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Oct 25, 2026, 7:55 AM EDT
Completed Not applicable Interventional Results available

Evaluation of the GORE Conformable TAG® for Treatment of Traumatic Transection

NCT00917852
View directory record Official record
Conditions
Thoracic Injuries
Interventions
Gore Conformable TAG Thoracic Endoprosthesis
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
26
States / cities
Los Angeles, California • Stanford, California • Jacksonville, Florida + 23 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2017 · Synced Oct 25, 2026, 7:55 AM EDT
Terminated Phase 2 Interventional Results available

Nintedanib Compared With Placebo in Treating Against Radiation-Induced Pneumonitis in Patients With Non-small Cell Lung Cancer That Cannot Be Removed by Surgery and Are Undergoing Chemoradiation Therapy

NCT02452463
View directory record Official record
Conditions
Lung Non-Squamous Non-Small Cell Carcinoma, Radiation-Induced Pneumonitis, Stage II Lung Non-Small Cell Cancer AJCC v7, Stage IIA Lung Non-Small Cell Carcinoma AJCC v7, Stage IIB Lung Non-Small Cell Carcinoma AJCC v7, Stage III Lung Non-Small Cell Cancer AJCC v7, Stage IIIA Lung Non-Small Cell Cancer AJCC v7, Stage IIIB Lung Non-Small Cell Cancer AJCC v7, Stage IV Lung Non-Small Cell Cancer AJCC v7
Interventions
Durvalumab, Nintedanib, Placebo, Quality-of-Life Assessment
Biological · Drug · Other + 1 more
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Oct 25, 2026, 7:55 AM EDT
Completed Not applicable Interventional Results available

Clinical Study of the U-Plate Fracture Repair System to Treat Rib Fractures

NCT00556543
View directory record Official record
Conditions
Rib Fracture, Flail Chest
Interventions
U-plate fracture repair system
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 1, 2011 · Synced Oct 25, 2026, 7:55 AM EDT
Terminated Not applicable Interventional

Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma

NCT06626334
View directory record Official record
Conditions
Rib Fractures, Pain, Acute
Interventions
Bright Blue Light, Bright Full-Spectrum (White) Light, Usual Ambient Light
Device
Lead sponsor
Rebecca E Kotcher, MD
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 25, 2026, 7:55 AM EDT