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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
CMC Arthritis, Occupational Therapy, Hand Arthritis
Interventions
Occupational Therapy, Home Exercise Program
Behavioral
Lead sponsor
Julie Nuelle
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Basilar Thumb Arthritis
Interventions
Suture Tape Reconstruction
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Detroit, Michigan
Completed Phase 2 Interventional Results available

Mechanisms of a Dynamic Stability Approach

NCT05247398
Conditions
Thumb Carpometacarpal Osteoarthritis, Thumb Basal Joint Osteoarthritis
Interventions
Dynamic Stability Exercise Program
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Arthritis
Interventions
Theraworx, Placebo
Drug
Lead sponsor
John Fowler
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania
Conditions
Carpometacarpal Thumb Arthritis
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Not listed Not applicable Interventional Accepts healthy volunteers

The Prevalence of the Linburg-Comstock Variation

NCT06142370
Conditions
Anomaly; Hand
Interventions
Descriptive
Other
Lead sponsor
Russell Sage College
Other
Eligibility
35 Years to 89 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Albany, New York
Conditions
Osteoarthritis, Osteoarthritis Thumb Base Joint, Carpometacarpal Osteoarthritis, Thumb
Interventions
CTM, Placebo
Device · Other
Lead sponsor
Indiana Hand to Shoulder Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions
Arthroplasty
Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Pain, Osteoarthritis
Interventions
Standard of Care Hand Therapy
Other
Lead sponsor
Gannon University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ruskin, Florida
Conditions
Carpometacarpal (CMC) Osteoarthritis
Interventions
Triamcinolone Acetonide extended release suspension
Drug
Lead sponsor
Marie Badalamente
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Stony Brook, New York
Conditions
Carpometacarpal Sprain, Thumb Sprain, Clostridium; Botulinum
Interventions
Botulinum toxin, Standard-of-care corticosteroid injections
Drug
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Arthritis
Interventions
Micro-Fragmented Adipose Tissue (MFAT), Triamcinolone Acetonide 10mg/mL
Biological · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Function Following Thumb MP Fusion and IP Fusion

NCT03661281
Conditions
Osteoarthritis
Interventions
Jebsen Taylor Hand function test, Pinch strength, Grooved pegboard test
Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Thumb Osteoarthritis
Interventions
Ketorolac, Triamcinolone
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Arthritis
Interventions
Meniscal allograft arthroplasty of the carpometacarpal joint of the thumb
Procedure
Lead sponsor
Corewell Health East
Other
Eligibility
25 Years to 95 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Royal Oak, Michigan
Conditions
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
3
States / cities
Rochester, Minnesota • New York, New York • Nashville, Tennessee
Conditions
Osteoarthritis Thumb
Interventions
Trapeziectomy with ligament reconstruction (I; LRTI), Trapeziectomy with suture suspensionplasty (II; SS), Arthroscopic Trapeziectomy (III; AT)
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
21 Years and older
Enrollment
165 participants
Timeline
2020 – 2027
U.S. locations
1
States / cities
Lebanon, New Hampshire
Conditions
Carpometacarpal Osteoarthritis
Interventions
Synvisc (hylan G-F20)
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
45 Years to 95 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
New York, New York
Conditions
Carpometacarpal Osteoarthritis
Interventions
Acetaminophen, Placebo: Multivitamin
Drug · Other
Lead sponsor
Indiana Hand to Shoulder Center
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Osteoarthritis
Interventions
Cell injection
Procedure
Lead sponsor
Texas Plastic Surgery
Industry
Eligibility
25 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Arthritis, Joint Diseases
Interventions
Ligament reconstruction tendon interposition, Suspensionplasty with one-suture construct, Suspensionplasty with two-suture construct
Procedure
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Osteoarthritis
Interventions
Synvisc (Hylan G-F20; hyaluronan injection), Bupivicaine (local anesthesia injection), Kenalog (triamcinolone; corticosteroid injection)
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
45 Years to 95 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Results available

LRTI vs Internal Brace for CMC OA

NCT03971188
Conditions
Thumb Carpometacarpal Osteoarthritis
Interventions
Trapeziectomy with Internal Brace
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
50 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
St Louis, Missouri
Conditions
Arthritis of Carpometacarpal Joint of Left Thumb, Arthritis of Carpometacarpal Joint of Right Thumb
Interventions
Curcumin, Placebo
Drug
Lead sponsor
Brent DeGeorge
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia