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ClinicalTrials.gov public records Last synced Oct 26, 2026, 9:14 PM EDT

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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Thumb Arthritis Clear all
Recruiting Not applicable Interventional

Turmeric for Patients With Basal Joint Arthritis

NCT03017118
View directory record Official record
Conditions
Thumb Osteoarthritis
Interventions
Turmeric, Placebo
Dietary Supplement · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 26, 2026, 9:14 PM EDT
Completed Not applicable Interventional

Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition

NCT01425034
View directory record Official record
Conditions
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions
casts for the thumb, Motion group
Other
Lead sponsor
University of Utah
Other
Eligibility
40 Years to 80 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 26, 2026, 9:14 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Oval-8 Splinting Versus Standardized Treatment With Tee Pee or Forearm Based Thumb Spica Splinting

NCT02266095
View directory record Official record
Conditions
Carpometacarpal (CMC) Joint Arthritis
Interventions
Oval-8 Splint, Tee Pee Splint, Forearm Based Splint
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 4, 2016 · Synced Oct 26, 2026, 9:14 PM EDT
Completed No phase listed Observational

Allograft Meniscal Arthroplasty for the Treatment of Basal Joint Arthritis of the Thumb

NCT01542515
View directory record Official record
Conditions
Arthritis
Interventions
Meniscal allograft arthroplasty of the carpometacarpal joint of the thumb
Procedure
Lead sponsor
Corewell Health East
Other
Eligibility
25 Years to 95 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 25, 2014 · Synced Oct 26, 2026, 9:14 PM EDT
Not listed Not applicable Interventional

Use of Autologous Adipose-Derived Stromal Vascular Fraction To Treat Osteoarthritis of Hip, Knee, Ankle, and Thumb Joints

NCT03166410
View directory record Official record
Conditions
Osteoarthritis
Interventions
Cell injection
Procedure
Lead sponsor
Texas Plastic Surgery
Industry
Eligibility
25 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 26, 2026, 9:14 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Embo Registry; National Registry for Artery Embolization

NCT06477965
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder, Pain, Chronic, Tendonitis Elbow, Tendonitis Shoulder, Tendonitis;Achilles, Tenosynovitis
Interventions
Artery Embolization
Procedure
Lead sponsor
Vascular Solutions of North Carolina
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
2
States / cities
Cary, North Carolina • Winchester, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Oct 26, 2026, 9:14 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Is Topical CBD Effective in Treating Thumb Joint Arthritis

NCT04611347
View directory record Official record
Conditions
CBD, Hand Osteoarthritis
Interventions
CBD, Shea Butter
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 26, 2026, 9:14 PM EDT
Completed Phase 3 Interventional Results available

A Study of Hyaluronan for the Treatment of Osteoarthritis in the Thumb

NCT00398866
View directory record Official record
Conditions
Osteoarthritis
Interventions
Synvisc (Hylan G-F20; hyaluronan injection), Bupivicaine (local anesthesia injection), Kenalog (triamcinolone; corticosteroid injection)
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
45 Years to 95 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 26, 2026, 9:14 PM EDT
Not listed Not applicable Interventional

Psychosocial Factors a Prognostic Study of Pain in Patients With CMC Osteoarthritis

NCT03821298
View directory record Official record
Conditions
Pain, Osteoarthritis
Interventions
Standard of Care Hand Therapy
Other
Lead sponsor
Gannon University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ruskin, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Oct 26, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Function Following Thumb MP Fusion and IP Fusion

NCT03661281
View directory record Official record
Conditions
Osteoarthritis
Interventions
Jebsen Taylor Hand function test, Pinch strength, Grooved pegboard test
Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 26, 2026, 9:14 PM EDT
Completed No phase listed Observational

The Impact of Thumb Carpometacarpal Osteoarthritis on General Health

NCT01133197
View directory record Official record
Conditions
Thumb Arthritis
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 29, 2015 · Synced Oct 26, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional

Trapeziectomy and Suture Suspensionplasty for Thumb Carpometacarpal Arthritis - Is In-Clinic Therapy Needed?

NCT06820528
View directory record Official record
Conditions
CMC Arthritis, Occupational Therapy, Hand Arthritis
Interventions
Occupational Therapy, Home Exercise Program
Behavioral
Lead sponsor
Julie Nuelle
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 26, 2026, 9:14 PM EDT
Completed Not applicable Interventional Results available

Pulsed Electromagnetic Field (PEMF) Therapy in Thumb CMC Arthritis

NCT05315297
View directory record Official record
Conditions
Thumb Osteoarthritis
Interventions
PEMF device, Sham PEMF device
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 26, 2026, 9:14 PM EDT
Recruiting Phase 3 Interventional

NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis

NCT05992883
View directory record Official record
Conditions
Thumb Osteoarthritis
Interventions
Ketorolac, Triamcinolone
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 26, 2026, 9:14 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Prevalence of the Linburg-Comstock Variation

NCT06142370
View directory record Official record
Conditions
Anomaly; Hand
Interventions
Descriptive
Other
Lead sponsor
Russell Sage College
Other
Eligibility
35 Years to 89 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 26, 2026, 9:14 PM EDT
Recruiting No phase listed Observational

Study on Basal Joint Arthritis Prospective

NCT01376024
View directory record Official record
Conditions
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
3
States / cities
Rochester, Minnesota • New York, New York • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 26, 2026, 9:14 PM EDT
Completed Phase 1 Interventional

AP-011 Study to Evaluate the Safety of a Single Intra-articular Injection of Ampion™ for Arthritis of the Basal Thumb Joint

NCT02762760
View directory record Official record
Conditions
Osteoarthritis of the Hand
Interventions
AMPION™, Saline
Biological
Lead sponsor
Ampio Pharmaceuticals. Inc.
Industry
Eligibility
40 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 15, 2016 · Synced Oct 26, 2026, 9:14 PM EDT
Completed Not applicable Interventional

Suture Fixation System Versus Tendonous Reconstruction in Carpometacarpal (CMC) Arthroplasty

NCT01121874
View directory record Official record
Conditions
Thumb Carpometacarpal Arthritis
Interventions
Ligament reconstruction with suture fixation system, Ligament Reconstruction with Tendon Interposition (LRTI)
Procedure
Lead sponsor
J&M Shuler
Industry
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 26, 2026, 9:14 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Prolotherapy Versus Steroids for Thumb Carpo-metacarpal Joint Arthritis

NCT00685880
View directory record Official record
Conditions
Thumb Carpometacarpal Joint Osteoarthritis
Interventions
Prolotherapy (10% dextrose solution), Betamethasone
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
45 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 30, 2012 · Synced Oct 26, 2026, 9:14 PM EDT
Completed No phase listed Observational

CMC Arthritis - Neoprene Vs. Thermoplast Short Opponens Splinting

NCT00438763
View directory record Official record
Conditions
Carpometacarpal Thumb Arthritis
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 27, 2013 · Synced Oct 26, 2026, 9:14 PM EDT
Completed Phase 4 Interventional

Use of FlexHD as Post Trapeziectomy Spacer

NCT01998594
View directory record Official record
Conditions
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions
Arthroplasty
Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Oct 26, 2026, 9:14 PM EDT
Terminated Not applicable Interventional Results available

Trapeziectomy: Internal Brace vs. Ligament Reconstruction (Prospective)

NCT05753891
View directory record Official record
Conditions
Basilar Thumb Arthritis
Interventions
Suture Tape Reconstruction
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 26, 2026, 9:14 PM EDT
Completed Phase 3 Interventional Results available

Impact of TheraWorx Foam on Symptom Relief in Thumb Arthritis

NCT03770091
View directory record Official record
Conditions
Arthritis
Interventions
Theraworx, Placebo
Drug
Lead sponsor
John Fowler
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Oct 26, 2026, 9:14 PM EDT