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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Tissue Tightening Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Ultherapy® for Treating the Face and Neck Using Standard Versus Simulines Transducers

NCT02416076
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera Treatment at EL2, Ulthera Treatment at EL4
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
3
States / cities
Beverly Hills, California • Saratoga, California • Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2019 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Application of the Apsara Thermal Wand System

NCT00662389
View directory record Official record
Conditions
Tightening of Skin Laxity
Interventions
Apsara Thermal Wand System
Device
Lead sponsor
Apsara Medical Corporation
Industry
Eligibility
40 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2009 · Synced Sep 5, 2026, 10:53 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Evaluation of the Ulthera® System for Treatment of the Face and Neck

NCT01713907
View directory record Official record
Conditions
Wrinkles, Rhytids, Skin Laxity
Interventions
Ulthera® Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Evaluation of the Ulthera® System for Treatment of Abdominal Tissue

NCT01708499
View directory record Official record
Conditions
Skin Laxity, Skin Crepiness
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
25 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment of the Face and Neck With Lower Ulthera System Energy Settings

NCT01713998
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 10, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Quantitative Evaluation of Skin Shrinkage Caused by a Non-invasive Tightening Device

NCT00894244
View directory record Official record
Conditions
Healthy
Interventions
Radiofrequency device
Device
Lead sponsor
Northwestern University
Other
Eligibility
30 Years to 60 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 27, 2021 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Assessment of Skin Tightening and Contour Change of Submental Tissue Using Bipolar Radiofrequency Microneedling

NCT04477187
View directory record Official record
Conditions
Skin Laxity
Interventions
Dermal Handpiece
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lifting and Tightening of the Face and Neck Following an Increased Density Treatment

NCT01519206
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 10, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of a 2,910 nm Fractional Ablative Fiber Laser (UltraClear®) for Improvements of Skin Laxity and Lifting of the Lower Face, Submental, and Neck Treatment Areas

NCT07759817
View directory record Official record
Conditions
Skin Laxity (Submental and Neck), Skin Lifting and Tightening
Interventions
2910 nm fiber laser (UltraClear®)
Device
Lead sponsor
FA Corporation
Industry
Eligibility
35 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Prospect, Kentucky • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lifting and Tightening of the Face in Subjects With Skin of Darker Color

NCT01368965
View directory record Official record
Conditions
Facial Skin Laxity
Interventions
Ulthera® System treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
2
States / cities
Chevy Chase, Maryland • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Evaluation of Ulthera Versus Thermage for Treating the Face and Neck

NCT01713985
View directory record Official record
Conditions
Skin Laxity, Wrinkles
Interventions
Ulthera System Treatment, Thermage
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Treatment of Post-surgery and Surgery Naive Patients Who Failed to Respond to a Previous Ulthera Treatment

NCT01708252
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Ulthera Treatment of the Buttocks and Thighs

NCT01708460
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Higher Density Ulthera® System Treatment With Vectoring for Treatment of the Face and Neck

NCT01708512
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
25 Years to 60 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Lifting and Tightening Neck Skin in Patients

NCT01708928
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Fractional Ablative Laser Treatment for Skin Conditions

NCT05750901
View directory record Official record
Conditions
Skin Laxity
Interventions
Fractional ablative laser
Device
Lead sponsor
Sciton
Industry
Eligibility
18 Years to 85 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ultherapy™ Treatment Following Sculptra® Treatment

NCT01422538
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera® System, Sculptra®, Sculptra® treatment followed by Ultherapy™ treatment
Device · Drug · Other
Lead sponsor
Ulthera, Inc
Industry
Eligibility
35 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

A Retrospective Study to Evaluate the Effectiveness of the Ulthera System

NCT01519934
View directory record Official record
Conditions
Skin Laxity, Wrinkles
Interventions
Not listed
Lead sponsor
Ulthera, Inc
Industry
Eligibility
25 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Study of the TruSculpt Radiofrequency Device

NCT03018587
View directory record Official record
Conditions
Tissue Tightening
Interventions
TruSculpt
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Brisbane, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Evaluation of the Ulthera® System for Treatment of the Knees

NCT01708434
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera® System
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Histological Characterization After Treatment With the Ulthera® System

NCT01713569
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Enrolling by invitation Not applicable Interventional

UVA-1 for Treatment of Skin Tightening and Improvement of Hand Function in Scleroderma

NCT04875078
View directory record Official record
Conditions
Scleroderma
Interventions
UVA-1 Phototherapy
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Sep 5, 2026, 10:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Study: Heavy Water Tissue Labeling Protocol

NCT01708525
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera® System Treatment, Heavy Water
Device · Other
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2017 · Synced Sep 5, 2026, 10:53 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Mechanical Coring to Achieve Directional Skin Tightening

NCT04910945
View directory record Official record
Conditions
Skin Tightening, Healthy Volunteers
Interventions
VENUS AIME (RoboCor)
Device
Lead sponsor
Venus Concept
Industry
Eligibility
30 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
3
States / cities
Los Altos, California • San Jose, California • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Sep 5, 2026, 10:53 PM EDT