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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:13 AM EDT

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Showing 169–192 of 1,798 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Tobacco Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Randomized Controlled Trial Methods for Novel Tobacco Products Evaluation

NCT02342795
View directory record Official record
Conditions
Nontherapeutic
Interventions
e-cigarette, cigarette substitute
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years to 65 Years
Enrollment
520 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
2
States / cities
Hershey, Pennsylvania • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 7, 2018 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Empower Korean Families to End Tobacco Use & Smoking Exposure

NCT04079569
View directory record Official record
Conditions
Smoking Cessation, Lifestyle Risk Reduction
Interventions
Tobacco, Healthy Living
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Leandro, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Developing Smokers for Smoker (S4S): A Collective Intelligence Tailoring System

NCT02265354
View directory record Official record
Conditions
Tobacco Smoking
Interventions
Collective-Intelligence computer tailored health communication, Rule-based computer tailored health communication
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
19 Years and older
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 21, 2026, 10:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

DECIDE: Developing Tools for Lung Cancer Screening Discussion Improvement

NCT03891602
View directory record Official record
Conditions
Smoking, Smoking, Tobacco, Smoking, Cigarette, Lung Cancer
Interventions
Cataldo Lung Cancer Stigma Scale (Smoking-Related Subscale), Patient Trust in the Medical, Decision Conflict Scale (DCS) - Lung Cancer Screening, Shared Decision Making Questionnaire (SDM-Q)- Patient, Stage of Readiness for Smoking Cessation - Contemplation Ladder, Primary Care Clinicians' Lung Cancer Screening Survey
Behavioral
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years to 80 Years
Enrollment
654 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 23, 2024 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Phase 3 Interventional

Efficacy and Safety of Dianicline Treatment as an Aid to Smoking Cessation in Cigarette Smokers (AMERIDIAN)

NCT00387946
View directory record Official record
Conditions
Smoking Cessation, Tobacco Use Cessation
Interventions
SSR591813L (dianicline)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
630 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 17, 2012 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effectiveness of Using Tobacco Free Snuff in Reducing Negative Effects of Smokeless Tobacco Use

NCT00218270
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Tobacco free snuff
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 70 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Contingency Management for Smoking Abstinence With Adolescent Smokers

NCT01056588
View directory record Official record
Conditions
Cigarette Smoking
Interventions
CO-Contingent, Control condition
Behavioral
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
13 Years to 19 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Phase 4 Interventional

Combination Medications vs. Patch Alone for Medically-Ill Smokers

NCT00770666
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine patch, nicotine inhaler, bupropion, Nicotine patch
Drug
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 10, 2008 · Synced Oct 21, 2026, 10:13 AM EDT
Withdrawn Phase 1 Interventional

Trial of Computerized MET for Adolescent Substance Use

NCT01784653
View directory record Official record
Conditions
Drug Abuse, Alcohol Abuse, Nicotine Dependence
Interventions
iMET, MET
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Oct 21, 2026, 10:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Modulation of Genes Responsible for Cilia Length by Exposure to Cigarette Smoke

NCT02168673
View directory record Official record
Conditions
COPD, Smoking
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2016 · Synced Oct 21, 2026, 10:13 AM EDT
Recruiting Not applicable Interventional

Reach Through Equitable Implementation in Utah

NCT06881069
View directory record Official record
Conditions
Tobacco Use Cessation, Tobacco Use, Tobacco Smoking, Tobacco Chewing, Tobacco Dependence
Interventions
Clinic Level: AAC - SDOH, AAC - Tobacco, Non-Bundled, Bundled, Dose 1, Dose 3, Dose 6, Dose 9, Dose 12, RPN, PPN
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
1,560 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Strategies to Promote Cessation in Smokers Who Are Not Ready To Quit

NCT02905656
View directory record Official record
Conditions
Smoking Cessation
Interventions
Brief Advice, Motivational Interviewing, Rate Reduction, Pharmacological, MI+RR
Behavioral · Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
903 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 1, 2024 · Synced Oct 21, 2026, 10:13 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Primary Care iSBIRT to Reduce Serious Teen Health Risks

NCT00891631
View directory record Official record
Conditions
Substance-related Disorders, Depression, High-risk Sex
Interventions
iSBIRT, iSBIRT/TE
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2016 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Modern Nicotine Oral Product Abuse Liability

NCT06777784
View directory record Official record
Conditions
Smoking, Tobacco Use
Interventions
Product A, Product B, Product C, Product D, Product E, Product F, Product G, Product N
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Lexington, Kentucky • Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Smoker Utilization of the Minnesota Quitline Through Support Persons

NCT01311830
View directory record Official record
Conditions
Tobacco Use
Interventions
Telephone Counseling, Written Materials
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
534 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 23, 2011 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Consumer Perceptions of Waterpipe Tobacco Packaging and Digital Marketing Claims

NCT05439421
View directory record Official record
Conditions
Waterpipe Tobacco Smoking
Interventions
Package/Advertisement With Claim, Package/Advertisement Without Claim
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 29 Years
Enrollment
1,507 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Oct 21, 2026, 10:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Tobacco Use Among Arab American Youth

NCT00059514
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Modified Project Toward No Tobacco Use
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
14 Years to 18 Years
Enrollment
2,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2006
U.S. locations
1
States / cities
Dearborn, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 21, 2026, 10:13 AM EDT
Completed No phase listed Observational

Medical Marijuana Use in HIV+ Patients Prospective Cohort Study

NCT01536899
View directory record Official record
Conditions
HIV Positive, Marijuana Smoking
Interventions
Not listed
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 70 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CSD190202: Study to Assess Elements of Abuse Liability for Two Electronic Nicotine Delivery Systems

NCT04094363
View directory record Official record
Conditions
Smoking, Tobacco Smoking, Tobacco Use
Interventions
Product A, Product B, Product C, Product D
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
2
States / cities
Knoxville, Tennessee • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced Oct 21, 2026, 10:13 AM EDT
Not yet recruiting Not applicable Interventional

Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study

NCT07001371
View directory record Official record
Conditions
Cannabis Use Disorder, Stimulant Use Disorder, Opioid Use Disorder, Tobacco Use Disorder, Alcohol Use Disorder, Sedative, Hypnotic, or Anxiolytic Use Disorders
Interventions
Emotional Brain Training, Standard addiction counseling and medical therapy
Behavioral · Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Bernardino, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Reduced Nicotine Cigarette Purchasing Decisions

NCT04999644
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Full Nicotine Cigarettes, Reduced Nicotine Cigarettes, Average Nicotine Expectancy, Very Low Nicotine Expectancy
Drug · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 9, 2024 · Synced Oct 21, 2026, 10:13 AM EDT
Completed No phase listed Observational

Tobacco-Focused Patient Navigation to Address Barriers to Utilization of Community-Based Smoking Cessation Services in Primary Care

NCT01678118
View directory record Official record
Conditions
Minority Smokers
Interventions
Patient Navigator
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of New Standards for Tobacco Products Among Dual E-Cigarette/Combusted Cigarette Users - Project 2

NCT05473585
View directory record Official record
Conditions
Smoking, Smoking, Cigarette, E-Cig Use, Nicotine Dependence
Interventions
very low nicotine content cigarettes, normal nicotine content cigarettes, Study e-cigarette
Other
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Oct 21, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Quit and Win Contests to Improve Smoking Cessation Among College Students

NCT01096108
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Standard contest (1 month), Motivational and Problem-Solving, Extended Contests
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
1,318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 22, 2014 · Synced Oct 21, 2026, 10:13 AM EDT