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ClinicalTrials.gov public records Last synced Oct 13, 2026, 8:18 PM EDT

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Showing 289–312 of 1,795 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Tobacco Products Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Developing a Smartphone App With Mindfulness Training for Teen Smoking Cessation

NCT02218281
View directory record Official record
Conditions
Cigarette Smoking
Interventions
C2Q-Teen app, NCI's QuitSTART app, Written smoking cessation materials only
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
13 Years to 19 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 26, 2016 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Not applicable Interventional

Feasibility, Acceptability and Fidelity of Integrating a Navigation Intervention Into Tobacco Treatment Program

NCT07072312
View directory record Official record
Conditions
Cancer
Interventions
Adjuvant Patient Navigation for Tobacco Treatment
Behavioral
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 13, 2026, 8:18 PM EDT
Recruiting Not applicable Interventional

Neuroimaging of Adolescent Cannabis Use Treatment

NCT07340554
View directory record Official record
Conditions
Cannabis Use, Cannabis Dependence, Cannabis Use Disorder, Cannabis Abuse, Cannabis Intoxication, Cannabis Smoking, Cannabis Withdrawal, Cannabis-Related Disorder, Cannabis Abuse, in Remission, Cannabis Abuse, Episodic Use, Marijuana, Marijuana Abuse, Marijuana Use, Marijuana Smoking, Marijuana Dependence, Marijuana User, Marijuana-Related Disorder, Marijuana Use Disorder, Addiction, Addiction, Substance, Substance Use, Substance Use Disorders, Substance Dependence, Substance Abuse, Substance Related Problem, Substance Abuse Drug Chronic
Interventions
Contingency Management, Elastic Net Regression
Behavioral · Device
Lead sponsor
Indiana University
Other
Eligibility
14 Years to 17 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Clinical Trial to Reduce Harm From Tobacco

NCT02328794
View directory record Official record
Conditions
Smoking Cessation
Interventions
E-cigarette free access, E-cigarette/NRT/Zyban/Chantix Choice, Outcome Incentive arm, Loss framing incentive arm, Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
6,006 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CSD170401: Study to Assess Elements of Abuse Liability for Three Electronic Tobacco Vapor Products During an 11-Day In-Clinic Confinement

NCT03126357
View directory record Official record
Conditions
Smoking
Interventions
Product A, Product B, Product C, Product D, Product E
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 27, 2017 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Phase 2 Interventional Results available

Computer-Assisted Intervention for Smoking During Pregnancy

NCT01028131
View directory record Official record
Conditions
Smoking
Interventions
Computer-delivered brief intervention (5As), Contingency Management
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 10, 2013 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Not applicable Interventional Results available

E-cigarettes to Promote Smoking Reduction Among Individuals With Schizophrenia

NCT02918630
View directory record Official record
Conditions
Tobacco Smoking
Interventions
Nicotine Patch, E-cigarette
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Switching to a Vaping Device: Evaluating Risk Reduction Among Quitline Treatment Failures

NCT03502200
View directory record Official record
Conditions
Smoking, Cigarette
Interventions
JUUL, Treatment As Usual
Device · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 99 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 21, 2023 · Synced Oct 13, 2026, 8:18 PM EDT
Terminated Not applicable Interventional

Motivational Interviewing for Stroke

NCT06195007
View directory record Official record
Conditions
Acute Stroke, Transient Ischemic Attack
Interventions
Motivational Interview
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Phase 2 Interventional

N-Acetylcysteine and Smoking Reduction

NCT00751257
View directory record Official record
Conditions
Nicotine Dependence
Interventions
N-acetylcysteine, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 23, 2017 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Comparison of Standard Versus Extended Nicotine Patch Therapy for Smoking Cessation

NCT00364156
View directory record Official record
Conditions
TOBACCO USE CESSATION
Interventions
Standard Patch Treatment, 24-weeks of nicotine patch
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
568 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 28, 2018 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Learning-Theory-Based Smoking Cessation Strategies

NCT01368653
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Standard treatment, Standard treatment+practice quitting, Very low nicotine cigarettes
Behavioral · Drug
Lead sponsor
Rutgers University
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 13, 2026, 8:18 PM EDT
Completed No phase listed Observational

Tobacco Craving and Triggers in Persons With Schizophrenia

NCT01846065
View directory record Official record
Conditions
Smoker, Schizophrenia Diagnosis
Interventions
Not listed
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Oct 13, 2026, 8:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating the Relationship Between Tobacco Use, Anxiety Sensitivity, and Panic in Adolescents

NCT00535964
View directory record Official record
Conditions
Panic Disorder
Interventions
Not listed
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
12 Years to 17 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Nov 17, 2022 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Not applicable Interventional

Study on Sit to Quit Phone Intervention

NCT02840435
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Sit to Quit, Quit for Life
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 13, 2019 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing Legally Feasible Options Studies 2/3

NCT05604508
View directory record Official record
Conditions
Tobacco Use
Interventions
Many posters with prices, Many posters, no prices, Fewer posters, no price restrictions
Other
Lead sponsor
RAND
Other
Eligibility
18 Years to 20 Years
Enrollment
445 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pharmacokinetics and Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC)

NCT05658471
View directory record Official record
Conditions
Nicotine Dependence, Tobacco Toxicity, Cardiovascular Risk Factors
Interventions
Standardized Research E-Cigarette (SREC), Over the Counter E-Cigarette (EC), Biological Samples, Smoking-related Questionnaires
Other · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 70 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 13, 2026, 8:18 PM EDT
Active, not recruiting Phase 4 Interventional

Smoking Cessation Program in the Construction Sector

NCT06098144
View directory record Official record
Conditions
Smoking Cessation, Tobacco Use Cessation, Tobacco Smoking
Interventions
Nicorette, Tobacco Quit-line, Brief Behavioral Counseling, Intensive Behavioral Counseling
Drug · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
608 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Biomarker Feedback for Smoking Cessation

NCT02206971
View directory record Official record
Conditions
Cigarette Smoking
Interventions
urine analyses feedback
Other
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 10, 2020 · Synced Oct 13, 2026, 8:18 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Veteran Social Support for Enhancing Use of Smoking Cessation Treatment

NCT05868421
View directory record Official record
Conditions
Smoking Cessation, Veterans Health
Interventions
Support Person Coaching Call, SP written materials, Written Smoking Cessation Materials
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
2,376 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 13, 2026, 8:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Nicotinic Modulation of the Default Network of Resting Brain Function

NCT01240616
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
21 Years to 55 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
2
States / cities
Baltimore, Maryland • Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

The Interaction of Flavor With Nicotine Form in Adult Smokers

NCT04262817
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Nicotine form, E-cigarette experimental flavor
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 26, 2023 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Creating Smokefree Living Together for Chinese Household Pairs

NCT01592682
View directory record Official record
Conditions
Smoking, Smoke Exposure
Interventions
Smokefree counseling
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Oct 13, 2026, 8:18 PM EDT
Completed Not applicable Interventional Results available

Goal2Quit + NRT Sampling

NCT03837379
View directory record Official record
Conditions
Cigarette Smoking, Smoking Cessation, Depression
Interventions
Treatment as Usual, Goal2Quit + NRT Sampling
Behavioral · Combination Product
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Oct 13, 2026, 8:18 PM EDT