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ClinicalTrials.gov public records Last synced Oct 9, 2026, 5:34 AM EDT

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Showing 73–96 of 1,795 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Tobacco Products Clear all
Completed Phase 4 Interventional

Young Hearts, Strong Starts

NCT01893593
View directory record Official record
Conditions
Cardiovascular Risk Reduction
Interventions
Intervention, Control
Other
Lead sponsor
RTI International
Other
Eligibility
3 Years to 11 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Chicago, Illinois • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2014 · Synced Oct 9, 2026, 5:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Abuse Liability for Five Modern Oral Nicotine Products

NCT07132814
View directory record Official record
Conditions
Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking
Interventions
Product A, Product B, Product C, Product D, Product E, Product F, Product N
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Phase 4 Interventional Results available

Post-Discharge Smoking Cessation Strategies: Helping HAND 4

NCT03603496
View directory record Official record
Conditions
Smoking Cessation
Interventions
Transitional Tobacco Care Management (TTCM), eReferral to State Tobacco Quitline (QL), Nicotine replacement therapy
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
1,416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Boston, Massachusetts • Pittsburgh, Pennsylvania • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 5, 2022 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Phase 3 Interventional Results available

Hutchinson Smoking Prevention Project

NCT00115869
View directory record Official record
Conditions
Smoking Among Youth
Interventions
Social-influences
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
7 Years to 9 Years
Enrollment
8,388 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1984 – 1999
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 29, 2012 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional Results available

Implementation of HIT-Enhanced Tobacco Treatment for Hospitalized Smokers

NCT01691105
View directory record Official record
Conditions
Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
Interventions
AD + Integrated Tobacco Order Set
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
1,044 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing Financial Incentive Interventions in Dyadic-Smoker Couples

NCT04832360
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Financial Incentives
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 24, 2025 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional

Computer Delivered and Community Health Worker Supported Smoking Cessation Intervention

NCT04566159
View directory record Official record
Conditions
Tobacco Smoking
Interventions
CBI-CHW, Standard Care
Behavioral · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CSD201204 An Actual Use Study of P12 Electronic Nicotine Delivery System Among U.S. Adult Smokers

NCT05960305
View directory record Official record
Conditions
Smoking, Tobacco
Interventions
P1213416, P1213422, P1213716, P1213722, P1211216, P1211222, P1213616, P1213622, P1213816, P1213822, P1211916, P1211922
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
1,845 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
12
States / cities
Phoenix, Arizona • Fort Lauderdale, Florida • Orlando, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2024 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers

NCT05023096
View directory record Official record
Conditions
Electronic Nicotine Delivery System Flavors
Interventions
Tobacco product administration and assessment
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years and older
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 9, 2026, 5:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Multi-Site Study to Assess the Effect of Availability of a Heated Tobacco Product on Smoking Abstinence Among Current Primary Cigarette Smokers

NCT07710820
View directory record Official record
Conditions
Smoking, Tobacco
Interventions
31237616, 31237617, 31237571, 31237581
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 65 Years
Enrollment
1,060 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
9
States / cities
Brandon, Florida • Coral Springs, Florida • Aurora, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healthier Hearts and Brains in Treating Smoking: The HABITS Study

NCT00581464
View directory record Official record
Conditions
Smoking
Interventions
Standard Behavioral Therapy, Mindfulness Based Addiction Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional Results available

Smoking Cessation Pilot for People Living With HIV (PLWH)

NCT04808609
View directory record Official record
Conditions
Smoking Cessation, Smoking, Smoking Behaviors, Smoking Reduction, Smoking, Tobacco, Smoking, Cigarette, Hiv, HIV/AIDS
Interventions
Lumme mobile phone application, Standard of Care
Device · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reactions to Reduced Nicotine Cigarettes in Young Adult Low-Frequency Smokers

NCT02989038
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Very Low Nicotine Content Cigarettes, Intermediate Nicotine Content Cigarettes, Normal Nicotine Content Cigarettes
Other
Lead sponsor
Duke University
Other
Eligibility
15 Years to 25 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional Results available

Examining the Generality of Laboratory-based Findings and Their Moderators in the ITC Study

NCT06456671
View directory record Official record
Conditions
Cigarette Smoking, Nicotine Vaping
Interventions
All nicotine/ tobacco products at market price, Nicotine vaping products at 1/2 market price, Heated tobacco products at 1/2 market price., Nicotine pouch products at 1/2 market price.
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
21 Years and older
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional

A Study of Tobacco Smoke and Children With Respiratory Illnesses

NCT03062709
View directory record Official record
Conditions
Bronchiolitis, Pneumonia, Reactive Airway Disease, Asthma, Tobacco Smoking, Tobacco Cessation, Bronchopulmonary Dysplasia
Interventions
Breathe Easy Coalition written materials, Maine Tobacco Helpline, Urine cotinine testing
Behavioral · Diagnostic Test
Lead sponsor
MaineHealth
Other
Eligibility
Up to 10 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional

Clinical Effort Against Smoke Exposure in Cystic Fibrosis

NCT04777344
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Tobacco Treatment Specialist (TTS) intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Oct 9, 2026, 5:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Support and Outreach to Increase Screening for Lung Cancer in Patients With a History of Smoking

NCT05679349
View directory record Official record
Conditions
Lung Carcinoma, Tobacco-Related Carcinoma
Interventions
Survey Administration, Educational Activity, Electronic Health Record Review, Counseling
Other
Lead sponsor
Ronald Myers
Other
Eligibility
50 Years to 77 Years
Enrollment
822 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing Legally Feasible Options: Study 1

NCT04259749
View directory record Official record
Conditions
Tobacco Use
Interventions
Flavor Ban, Menthol Ban, All flavored and mentholated products available
Other
Lead sponsor
RAND
Other
Eligibility
11 Years to 20 Years
Enrollment
267 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

High Impact E-cigarette Advertisement Features

NCT06704295
View directory record Official record
Conditions
Vaping Behavior
Interventions
Control ad with dark gray product with tobacco flavor name, Dark gray product with strawberry flavor name, Colorful (strawberry color) product with strawberry flavor name, Colorful (strawberry color) product with strawberry flavor name and image, Colorful (strawberry color) product with strawberry flavor features, Colorful (strawberry color) product with strawberry flavor features and choice claim
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 30 Years
Enrollment
3,083 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional Results available

Testing the Impact of Smartphone-based Messaging to Support Young Adult Smoking Cessation - Pilot

NCT05991934
View directory record Official record
Conditions
Tobacco Cigarette Smoking
Interventions
Smartphone-based intervention messages
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 30 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Oct 9, 2026, 5:34 AM EDT
Recruiting Phase 2 Interventional

Cannabidiol for Reducing Cigarette Use

NCT06218056
View directory record Official record
Conditions
Tobacco Use Disorder, Tobacco Smoking, Tobacco Dependence
Interventions
Cannabidiol (CBD) 800 mg, Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
North Hollywood, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Low Dose Aspirin Inhibition of COX-2 Derived PGE2 in Male Smokers

NCT01796951
View directory record Official record
Conditions
Tobacco Use Disorder, Smoking
Interventions
Aspirin 325 mg daily, Celecoxib 200 mg BID
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
35 Years to 90 Years · Male only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 9, 2026, 5:34 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Perceptions of E-Cigarettes and Synthetic Cooling Agents, The ICE Study

NCT06208202
View directory record Official record
Conditions
Abuse Tobacco, Exposure
Interventions
Behavioral Intervention, Biospecimen Collection, Survey Administration
Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 29 Years
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 9, 2026, 5:34 AM EDT
Completed Not applicable Interventional

Short Term Effects of Electronic Cigarettes in Tobacco Dependent Adults

NCT02498145
View directory record Official record
Conditions
Smoking, Nicotine Dependence
Interventions
Nicotine e-cigarette, Non-nicotine e-cigarette
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 9, 2026, 5:34 AM EDT