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Showing 1–24 of 2,051 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Tobacco Smoking Behavior Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

FRESH Delivers: An Innovative Approach to Reducing Tobacco Use Among Rural Smokers

NCT05429892
View directory record Official record
Conditions
Tobacco Cessation, Tobacco Dependence, Food Security
Interventions
Smoking cessation counseling and food delivery, Smoking cessation counseling, Food delivery
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
21 Years to 75 Years
Enrollment
540 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Behavioral Economic Analysis of Demand for Marijuana

NCT03518567
View directory record Official record
Conditions
Marijuana Smoking
Interventions
Smoked marijuana cigarettes: High THC dose (6% THC)
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years to 50 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 11, 2024 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family-Skills Training to Prevent Tobacco and Other Substance Use in Latino Youth

NCT01442753
View directory record Official record
Conditions
Tobacco Use Disorder, Alcohol Use Disorder, Drug Use Disorder, Smoking, Alcohol Drinking, Drug Abuse
Interventions
Family-Skills Training
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional

Text Messaging to Engage and Retain Veterans in Smoking Cessation Counseling

NCT03177265
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Text messaging prior to first counseling call, Text-to-Enhance, Mail Notice, Telephone Counseling
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
432 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
San Diego, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Jul 23, 2026, 7:05 PM EDT
Not listed Phase 3 Interventional

Implementing Tobacco Control in Dental Practice

NCT00297700
View directory record Official record
Conditions
Smoking
Interventions
Active referral
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years and older
Enrollment
2,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional Results available

Puff Biofeedback to Reduce Smoking Reinforcement

NCT05644002
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Puff Topography Biofeedback Training, Control
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
19 Years to 55 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 23, 2025 · Synced Jul 23, 2026, 7:05 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Resistance Training on Tobacco-Related Cardiovascular Disease Risk

NCT01705951
View directory record Official record
Conditions
Smoking, Cardiovascular Disease Risk
Interventions
Resistance Training (RT), Nicotine Replacement Therapy (NRT)
Other · Biological
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 11, 2012 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional Results available

Comparing Smoking Cessation Interventions Among Underserved Patients Referred for Lung Cancer Screening

NCT04798664
View directory record Official record
Conditions
Smoking Cessation
Interventions
Removal of Financial Barriers, Financial Incentives, Mobile Health Application
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
3,228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
5
States / cities
Oakland, California • Detroit, Michigan • Danville, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intervention Study to Increase Smoking Cessation Rates Among Public Housing Residents

NCT01651611
View directory record Official record
Conditions
Tobacco Cessation
Interventions
Motivational interviewing, Smoking cessation counseling, Navigation to smoking cessation resources, Social support
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 79 Years
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 28, 2016 · Synced Jul 23, 2026, 7:05 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Use of a Smartphone Mobile Application (App) to Enhance Smoking Cessation Treatment

NCT03519451
View directory record Official record
Conditions
Depression, Tobacco Use Disorder, Current Every Day Smoker
Interventions
Internet-Based Intervention, Questionnaire Administration
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional

A Usability Study of a Smoking Cessation Decision Aid in People With a Recent First Episode of Psychosis

NCT01399112
View directory record Official record
Conditions
Smoking, Psychosis
Interventions
Web-based computer program
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
15 Years to 30 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Glen Oaks, New York
Source: ClinicalTrials.gov public record
Updated Jan 2, 2013 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional

Technology and Telephone-Based Smoking Cessation

NCT03492645
View directory record Official record
Conditions
Smoking Cessation
Interventions
Telephone-and technology-facilitated treatment protocol, Office-based treatment protocol
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 69 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2019 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Trial of Using SmokeBeat to Monitor and Increase Smoking Abstinence in Pregnant Women

NCT03209557
View directory record Official record
Conditions
Tobacco Use Cessation, Pregnancy Related
Interventions
SmartWatch SmokeBeat Application
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2019 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional Results available

'Questions About Quitting' Smoking Cessation Trial

NCT00992264
View directory record Official record
Conditions
Smoking
Interventions
Message Tone, Navigation, Proactive Outreach, Testimonials
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,865 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Recruitment Messages for Current Smokers Recently Diagnosed With Cancer

NCT05471284
View directory record Official record
Conditions
Tobacco Smoking, Health Behavior
Interventions
Proximal, Distal, Cost, Benefit, Loss, Gain, Control
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 21, 2022 · Synced Jul 23, 2026, 7:05 PM EDT
Completed No phase listed Observational

Organochlorine Exposure in Relation to Timing of Natural Menopause

NCT00353171
View directory record Official record
Conditions
Menopause
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
Not listed
Enrollment
514 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2019
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 16, 2019 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

eCEASE to Support Treatment for Parental Tobacco Use

NCT04974736
View directory record Official record
Conditions
Tobacco Smoking, Second Hand Tobacco Smoke, Smoking Cessation
Interventions
iEHR + Navigator
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
817 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2025 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Phase 3 Interventional

Theory-Based Interventions for Smoking and Obesity (Challenge) Trial

NCT00040287
View directory record Official record
Conditions
Smoking, Obesity
Interventions
smoking cessation program, weight control program
Behavioral
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 60 Years
Enrollment
1,778 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1999
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 16, 2007 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional Results available

Quit For Life (QFL): Smoking Cessation Among Chinese Smokers Living With HIV

NCT05020899
View directory record Official record
Conditions
Smoking Cessation, HIV Infections
Interventions
Sessions with a trained counselor, Cell phone messages, Offered nicotine replacement therapy, Self-help guide for quitting smoking
Behavioral · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2024 · Synced Jul 23, 2026, 7:05 PM EDT
Terminated Phase 3 Interventional Results available

Simvastatin Therapy for Moderate and Severe COPD

NCT01061671
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
simvastatin, Placebo
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
40 Years to 80 Years
Enrollment
885 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
35
States / cities
Birmingham, Alabama • Los Angeles, California • San Francisco, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jan 1, 2018 · Synced Jul 23, 2026, 7:05 PM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Centralized Lung Cancer EARly Detection Among Smokers (CLEAR Study)

NCT04200534
View directory record Official record
Conditions
Smoking, Lung Cancer
Interventions
Best Practice, Nicotine Patch, Quality-of-Life Assessment, Questionnaire Administration, Tobacco Cessation Counseling
Other · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
55 Years to 77 Years
Enrollment
358 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
3
States / cities
Galveston, Texas • Houston, Texas • Tyler, Texas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Jul 23, 2026, 7:05 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Smoke Free SafeCare: Establishing a Smoke Free Home in CPS-involved Families

NCT05000632
View directory record Official record
Conditions
Child Maltreatment, Smoking Behaviors
Interventions
Smoke Free SafeCare, Standard SafeCare
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
18 Years to 89 Years
Enrollment
268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving the Delivery of Smoking Cessation Guidelines in Hospitalized Veterans

NCT00816036
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Smoking Cessation Guideline Implementation
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
898 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
4
States / cities
Denver, Colorado • Iowa City, Iowa • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2015 · Synced Jul 23, 2026, 7:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers

NCT06644664
View directory record Official record
Conditions
Tobacco-Related Carcinoma
Interventions
Health Education, Interview, Smoking Cessation Intervention, Survey Administration, Text Message-Based Navigation Intervention
Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 35 Years
Enrollment
292 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Jul 23, 2026, 7:05 PM EDT