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ClinicalTrials.gov public records Last synced Oct 9, 2026, 6:14 AM EDT

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Showing 73–96 of 1,296 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Tobacco Smoking Cessation Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neural Basis of Eating Behavior in Abstinent Smokers

NCT03438188
View directory record Official record
Conditions
Nicotine Use Disorder
Interventions
Practice Quit Attempt
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Progesterone & Postpartum Relapse to Smoking

NCT01798394
View directory record Official record
Conditions
Tobacco Use Cessation, Tobacco Use Disorder
Interventions
Progesterone, Placebo
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 9, 2017 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Smoking Cessation for American Indians

NCT01106456
View directory record Official record
Conditions
Smoking Cessation
Interventions
All Nations Breath of Life (ANBL), Nontailored program (NT), Pharmacotherapy
Behavioral · Drug
Lead sponsor
Won Choi, PhD, MPH
Other
Eligibility
18 Years and older
Enrollment
463 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
2
States / cities
Kansas City, Kansas • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 26, 2017 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Combining a Smoke Ending Aid With Behavioral Treatment - 1

NCT00006151
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Behavioral Therapy
Behavioral
Lead sponsor
Peter Gariti
Other
Eligibility
21 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 3, 2015 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Randomized Controlled Trial of a Smart Phone-Based Smoking Cessation Program

NCT04955639
View directory record Official record
Conditions
Smoking Cessation
Interventions
Control, Pivot
Other
Lead sponsor
Jennifer Marler, MD
Industry
Eligibility
21 Years and older
Enrollment
188 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Carlos, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2024 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindset Intervention for Nicotine Dependence

NCT03174730
View directory record Official record
Conditions
Psychology, Social, Smoking Cessation, Smoking (Tobacco) Addiction
Interventions
Growth Mindset, SmartQuit
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
398 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 6, 2018 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Smoking Cessation for Veterans With Severe and Persistent Mental Illness

NCT00960375
View directory record Official record
Conditions
Schizoaffective Disorder, Schizophrenia, Affective Psychosis, Bipolar, Affective Disorders, Psychotic
Interventions
BTSCS, StSST
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 75 Years
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 18, 2015 · Synced Oct 9, 2026, 6:14 AM EDT
Withdrawn Phase 2 Interventional

Electronic Nicotine Delivery Systems as a Smoking Cessation Treatment

NCT02487953
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Nicotine patch, ENDS, Placebo patch, Placebo ENDS
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Bupropion Treatment for Youth Smoking Cessation

NCT00344695
View directory record Official record
Conditions
Nicotine Dependence
Interventions
bupropion SR
Drug
Lead sponsor
University of Arizona
Other
Eligibility
14 Years to 17 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
Ends 2003
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 27, 2006 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Not applicable Interventional

Quit IT: Preliminary Testing of a Web-based, 3D Coping Skills Game to Increase Quitting Self-Efficacy for Maintaining Smoking Abstinence Following Hospitalization

NCT02099097
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
web-based video game (Quit IT), Questionnaires, Salvia sample
Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 30, 2020 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Testing a Computer Delivered Tobacco Cessation Intervention in Outpatient Clinical Settings: A Feasibility Study

NCT05145738
View directory record Official record
Conditions
Tobacco Smoking
Interventions
C-Raven with avatar, C-Raven without avatar
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Oct 9, 2026, 6:14 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Equitable Smoking Relapse Prevention

NCT05625685
View directory record Official record
Conditions
Tobacco Use Disorder, Tobacco Dependence
Interventions
Quitbuddy, Control, SDoH Augmentation, SDoH Control
Other
Lead sponsor
Bryan W. Heckman
Other
Eligibility
21 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exploratory Study of Switching From Combustible Cigarettes to the BIDI E-cigarette

NCT05855343
View directory record Official record
Conditions
Smoking Cessation
Interventions
BIDI Stick e-cigarette
Other
Lead sponsor
Rose Research Center, LLC
Industry
Eligibility
22 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Charlotte, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Not applicable Interventional

Pediatric Emergency Department Decision Support System to Reduce Secondhand Smoke

NCT02489708
View directory record Official record
Conditions
Asthma, Smoking Cessation
Interventions
Cessation Counseling
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Day and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 9, 2021 · Synced Oct 9, 2026, 6:14 AM EDT
Terminated Not applicable Interventional

Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia

NCT05724810
View directory record Official record
Conditions
Schizophrenia, Smoking Cessation, Tobacco Use
Interventions
Active deep transcranial magnetic stimulation (dTMS), Sham dTMS
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 60 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smoking Prevention Through Social Connections Among Adolescents - ASPIRE

NCT02703597
View directory record Official record
Conditions
Tobacco Use Behavior
Interventions
Surveys, ASPIRE, GSA-ASPIRE-Network
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
11 Years to 18 Years
Enrollment
393 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Not applicable Interventional Results available

An Intervention to Reduce Second Hand Smoke Exposure Among Pediatric Emergency Patients

NCT02531594
View directory record Official record
Conditions
Smoking Cessation
Interventions
SBIRT, HHC
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
770 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Oct 9, 2026, 6:14 AM EDT
Terminated Phase 2 Interventional Results available

Pre to Postoperative Smoking Cessation

NCT02683161
View directory record Official record
Conditions
Cigarette Smoking, Obesity
Interventions
Varenicline, Contingency Management, Behavioral Counseling
Drug · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Smoking Cessation Aid for Young Smokers

NCT00340483
View directory record Official record
Conditions
Smoking Cessation
Interventions
Smoking cessation
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 22 Years
Enrollment
291 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 9, 2026, 6:14 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

NCT05452772
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Psilocybin, Niacin
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
3
States / cities
Birmingham, Alabama • Baltimore, Maryland • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Incentives for Oklahoma Tobacco Helpline Engagement in Persistent Poverty Counties

NCT05095779
View directory record Official record
Conditions
Cigarette Smoking, Nicotine Dependence
Interventions
Coaching calls, Nicotine replacement therapy, Financial Incentives
Behavioral · Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Not applicable Interventional

Increasing Cessation Motivation and Treatment Engagement Among Smokers in Pain

NCT03996902
View directory record Official record
Conditions
Chronic Pain, Smoking, Smoking Cessation
Interventions
Tailored intervention, Ask-Advise-Refer
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jun 25, 2019 · Synced Oct 9, 2026, 6:14 AM EDT
Active, not recruiting Not applicable Interventional

Post Acute Cardiac Event Smoking (PACES) Study

NCT03413423
View directory record Official record
Conditions
Acute Coronary Syndrome, Tobacco Use
Interventions
BAT-CS, Smoking Cessation and Health & Wellness
Behavioral
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Oct 9, 2026, 6:14 AM EDT
Completed Not applicable Interventional

Impact of Smoking and Its Cessation on Systemic and Airway Immune Activation

NCT02836067
View directory record Official record
Conditions
HIV, Smoking
Interventions
Counseling, Smoking Cessation drugs, Bronchoscopy, Blood Draw, Questionnaires
Behavioral · Other · Procedure
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2024 · Synced Oct 9, 2026, 6:14 AM EDT