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ClinicalTrials.gov public records Last synced Oct 9, 2026, 10:54 PM EDT

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Showing 97–120 of 1,296 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Tobacco Smoking Cessation Clear all
Completed Phase 1 Interventional

Enhanced Quitline Intervention in Smoking Cessation for Patients With Non-Metastatic Lung Cancer

NCT01457469
View directory record Official record
Conditions
Limited Stage Small Cell Lung Cancer, Recurrent Small Cell Lung Cancer, Stage IA Non-small Cell Lung Cancer, Stage IB Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lung Cancer, Stage IIB Non-small Cell Lung Cancer, Stage IIIA Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Tobacco Use Disorder
Interventions
questionnaire administration, quality-of-life assessment, counseling intervention, internet-based intervention, telephone-based intervention, educational intervention, nicotine replacement therapy
Other · Procedure · Behavioral + 1 more
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smokers

NCT00843622
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Low-nitrosamine smokefree tobacco product for oral use, Non-tobacco, non-nicotine placebo product
Drug · Other
Lead sponsor
Swedish Match AB
Industry
Eligibility
25 Years to 65 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
4
States / cities
Daytona Beach, Florida • Evansville, Indiana • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2014 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Varenicline For Smokers In Recovery From Alcohol Dependence

NCT01092702
View directory record Official record
Conditions
Tobacco Abstinence
Interventions
Varenicline
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 25, 2023 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Not applicable Interventional Results available

Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers

NCT01259466
View directory record Official record
Conditions
Smoking Cessation, Overweight, Obesity
Interventions
Nicotine patch
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 28, 2015 · Synced Oct 9, 2026, 10:54 PM EDT
Terminated Not applicable Interventional

Incentives to Promote Smoking Cessation in Low SES Women

NCT03173274
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Brief Motivational Intervention, Contingency Management, Non-Contingent Reinforcement
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 4, 2019 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Phase 4 Interventional Results available

Post-Discharge Smoking Cessation Strategies: Helping HAND 4

NCT03603496
View directory record Official record
Conditions
Smoking Cessation
Interventions
Transitional Tobacco Care Management (TTCM), eReferral to State Tobacco Quitline (QL), Nicotine replacement therapy
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
1,416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Boston, Massachusetts • Pittsburgh, Pennsylvania • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 5, 2022 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Internet Stop Smoking Study - Phase VI

NCT00721786
View directory record Official record
Conditions
Smoking
Interventions
UCSF/SFGH Internet Stop Smoking Study site
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
18,154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 15, 2018 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Framing Messages for Smoking Cessation With Bupropion - 6

NCT00104598
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Bupropion, Smoking Abstinence Program
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
252 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2006
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 9, 2013 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Smoking Cessation Intervention for Thoracic Patients

NCT00580398
View directory record Official record
Conditions
Lung Cancer
Interventions
Smoking cessation counseling, varenicline
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 9, 2026, 10:54 PM EDT
Recruiting Not applicable Interventional

Shaping Habitual Impulses For a Tobacco-free Style

NCT07025772
View directory record Official record
Conditions
ST+ABR, ST+SHAM, ST-only
Interventions
ST+ABR, ST+Sham, ST Only
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Phase 2 Interventional Results available

Acetylsalicylic Acid Compared to Placebo in Treating High-Risk Patients With Subsolid Lung Nodules

NCT02169271
View directory record Official record
Conditions
Current Smoker, Former Smoker, Multiple Pulmonary Nodules, Tobacco Use Disorder
Interventions
Aspirin, Laboratory Biomarker Analysis, Placebo
Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
50 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Phase 2 Interventional

Tobacco Treatment Optimization and Preferences During Concurrent Cancer Treatment

NCT04634071
View directory record Official record
Conditions
Smoking Cessation, Cancer, Treatment-Related
Interventions
Varenicline, Bupropion, Long-acting nicotine replacement therapy, Low-intensity counseling, High-intensity counseling, No nicotine replacement therapy, Nicotine Replacement Products
Drug · Behavioral · Other
Lead sponsor
Joseph Valentino, MD
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Bowling Green, Kentucky • Lexington, Kentucky • Owensboro, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Not applicable Interventional

Smoking Cessation for Low-Income Pregnant Women

NCT02211430
View directory record Official record
Conditions
Pregnancy, Smoking
Interventions
Cognitive-Behavioral Counseling (CBC), Best Practice (BC) Control
Behavioral
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
277 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2014 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating a Telephone-Based Smoking Cessation Program Among People in the Military (The AFIII Study)

NCT00632411
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
Nicotine Patch, Tobacco Quit Line Program
Drug · Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
1,298 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
2
States / cities
Memphis, Tennessee • Lackland Air Force Base, Texas
Source: ClinicalTrials.gov public record
Updated Mar 14, 2018 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healthier Hearts and Brains in Treating Smoking: The HABITS Study

NCT00581464
View directory record Official record
Conditions
Smoking
Interventions
Standard Behavioral Therapy, Mindfulness Based Addiction Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing a Novel Smartphone Application for Smoking Cessation With the Oklahoma Helpline

NCT05539209
View directory record Official record
Conditions
Smoking Cessation
Interventions
OKquit, Standard Helpline Care
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
512 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Phase 4 Interventional Results available

Behaviorally Enhanced Counseling on Nicotine Dependence (BEACON) Trial.

NCT00991081
View directory record Official record
Conditions
Smoking
Interventions
Counseling, Self-help guide, Pharmacotherapy, Genetic feedback, verbal, Genetic feedback, printed
Behavioral · Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
Menlo Park, California • Stanford, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 19, 2012 · Synced Oct 9, 2026, 10:54 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Measurement of Cancer-Related Risk Perception in Smokers

NCT00588211
View directory record Official record
Conditions
Cancer Related-Risks, Risk Perception, Survey, Focus Group
Interventions
Interviews, focus group, Survey
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
1,514 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2022
U.S. locations
4
States / cities
Jamaica, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2022 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Not applicable Interventional Results available

Hospital-based Patient Navigation and Smoking Cessation

NCT03452371
View directory record Official record
Conditions
Smoking Cessation
Interventions
Patient Navigation, Enhanced Traditional Care
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 31, 2020 · Synced Oct 9, 2026, 10:54 PM EDT
Not listed Not applicable Interventional

Smoking Cessation for People Living With HIV/AIDS

NCT01965405
View directory record Official record
Conditions
HIV, AIDS, Nicotine Dependence
Interventions
Bupropion, Brief Counseling, High-magnitude prize contingency management, Monitored support to quit smoking, No additional treatment, Prize contingency management for abstinence, Low intensity prize contingency management
Drug · Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 2, 2021 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Not applicable Interventional Results available

An Intervention to Reduce Second Hand Smoke Exposure Among Pediatric Emergency Patients

NCT02531594
View directory record Official record
Conditions
Smoking Cessation
Interventions
SBIRT, HHC
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
770 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Utilizing Augmented Reality as an Adjunct for Smoking Cessation

NCT04101422
View directory record Official record
Conditions
Smoking
Interventions
Augmented Reality 1, Augmented Reality 2, Augmented Reality 3, Augmented Reality 4
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
197 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Oct 9, 2026, 10:54 PM EDT
Recruiting Phase 2 Interventional

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

NCT06609369
View directory record Official record
Conditions
Tobacco Use, Tobacco Cessation, Insomnia
Interventions
Experimental health intervention, Varenicline
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 9, 2026, 10:54 PM EDT
Completed Not applicable Interventional Results available

Small Financial Incentives to Promote Smoking Cessation

NCT02737566
View directory record Official record
Conditions
Smoking Cessation
Interventions
Standard Care + Financial Incentives, Standard Care
Behavioral · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 9, 2026, 10:54 PM EDT