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ClinicalTrials.gov public records Last synced Nov 4, 2026, 1:07 PM EST

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Showing 1–24 of 706 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Tobacco Use Cessation Clear all

Conditions: Smoking Cessation, Tobacco Cessation
Interventions: Brochure, Counseling; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older · Female only
Enrollment: 212 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Tobacco Use Cessation
Interventions: Real-Time Smoking Intervention, Standard Treatment; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking Cessation
Interventions: Nicotine Patches, Telephone Counseling, Brief Hospital Counseling; Drug · Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 1,270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 6
States / cities: Chula Vista, California • Davis, California • La Jolla, California + 1 more

Conditions: Smoking Cessation, Smoking Behaviors, Smoking Reduction, Smoking, Cigarette, Smoking, Nicotine Dependence
Interventions: Clickotine®; Device
Lead sponsor: Click Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Tobacco-Related Carcinoma, Smoking Cessation
Interventions: Smoking cessation education, Survey Administration, Telephone-Based Intervention, Urine Specimen Collection, Silicone Wrist Band, Interview, Focus Group; Other · Behavioral · Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 760 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Nicotine Dependence
Interventions: Varenicline, placebo; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 14 Years to 21 Years
Enrollment: 157 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Cigarette Smoking
Interventions: Smoking counseling, Text messaging, Nicotine patch; Behavioral · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 24 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Nicotine Dependence
Interventions: Smoking Cessation Counseling; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Adherence, Tobacco Use Cessation, Alcohol & Drug Use, Nicotine Transdermal System
Interventions: Lifestyle counseling; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 25 Years
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 3
States / cities: Jacksonville, Florida • Rochester, Minnesota

Conditions: Tobacco Use, Smoking Cessation, Nicotine Dependence
Interventions: Ketamine Hydrochloride, Motivational enhancement therapy; Drug · Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years to 65 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Smoking Reduction, Tobacco Use, Tobacco Smoking, Tomography, Lung Diseases, Lung Neoplasms
Interventions: Unsigned note to provider about cessation medication prescription, Proactive Telephone Counseling from VA Quitline; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Up to 80 Years
Enrollment: 944 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 3
States / cities: New York, New York • Providence, Rhode Island • Seattle, Washington

Conditions: Tobacco Use Disorder
Interventions: nicotine transdermal system; Drug
Lead sponsor: New York University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 585 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 13
States / cities: Los Angeles, California • Tarzana, California • Miami, Florida + 8 more

Conditions: Smoking, Tobacco Use, Lung Cancer
Interventions: Nicotine patch and lozenges, Telephone counseling sessions, Access to a web-based video, Florida Tobacco Quitline; Drug · Behavioral
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Cigarette Smoking, Tobacco Use, Cigarette Smoking Behavior
Interventions: HRP Sampling period, NPL Sampling period; Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 21 Years and older
Enrollment: 472 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Nicotine Addiction, Smoking Cessation
Interventions: Computer Tablet; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 100 Years
Enrollment: 961 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 2
States / cities: San Francisco, California

Conditions: Smoking Cessation
Interventions: MoMba Live Long app & Sensordrone™ carbon-monoxide sensor, Office contingency management, Sensordrone™ carbon-monoxide sensor, MoMba Live Long Smartphone application; Behavioral · Device
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking, HIV Infections, AIDS
Interventions: Positively Smoke Free, Standard care; Behavioral
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 147 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Bipolar Disorder
Interventions: Bupropion, Placebo; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Tobacco Use Cessation, Tobacco Use, Tobacco Smoking, Tobacco Chewing, Tobacco Dependence
Interventions: Clinic Level: AAC - SDOH, AAC - Tobacco, Non-Bundled, Bundled, Dose 1, Dose 3, Dose 6, Dose 9, Dose 12, RPN, PPN; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 1,560 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Cigarette Smoking, Nicotine Dependence
Interventions: Coaching calls, Nicotine replacement therapy, Financial Incentives; Behavioral · Drug
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Schizophrenia, Smoking Cessation, Tobacco Use
Interventions: Active deep transcranial magnetic stimulation (dTMS), Sham dTMS; Device
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Smoking Cessation, Smoking Behaviors, Smoking, Tobacco, Smoking, Cigarette, Smoking (Tobacco) Addiction
Interventions: ACT Lung Health Intervention; Behavioral
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 18 Years to 100 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Cigarette Smoking
Interventions: Standard Treatment, Behavioral Activation Treatment for Smoking, Transdermal Nicotine Patch; Behavioral · Drug
Lead sponsor: University of Maryland, College Park; Other
Eligibility: 18 Years to 65 Years
Enrollment: 184 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: College Park, Maryland

Conditions: Nicotine Use Disorder, Smoking Cessation, Smoking Cessation Intervention
Interventions: Enhanced Courage to Quit; Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 26 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Search by objective public record fields.

P60 Program Project Grant-Outreach for Smoke-Free Homes

Evaluating the Feasibility and Efficacy of a Real-time Smoking Intervention Using Wearable Technology

Smoking Cessation in Hospitalized Smokers

Clinical Learning Study for a Mobile Smoking Cessation Program

Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities

Varenicline for Adolescent Smoking Cessation

Text Messaging for Smoking Cessation in College Health Clinics

Brain Activity and Smoking Cessation

Smoking Cessation for Young Adults Who Binge Drink - 1

Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder

Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment

Smoking Cessation Treatment With Transdermal Nicotine Replacement Therapy - 1

Project HEALS (Helping and Empowering pAtients for Living a Life Smoke-free

Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit

Computer-Facilitated 5A's for Smoking Cessation in Primary Care

Harnessing the Power of Technology: MOMBA for Postpartum Smoking

A Trial to Test the Efficacy of a Tailored Intensive Smoking Cessation Intervention in Persons With HIV (PWHs)

A Preliminary Study of Sustained-Release Bupropion for Smoking Cessation in Bipolar Affective Disorder

Reach Through Equitable Implementation in Utah

Incentives for Oklahoma Tobacco Helpline Engagement in Persistent Poverty Counties

Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia

ACT Lung Health Intervention: Phase Two

Behavioral Activation Intervention for Smoking Cessation in Smokers With Depressive Symptoms

Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites