Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 4, 2026, 6:24 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 677 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Tooth Disease Clear all
Completed Early Phase 1 Interventional

Intensive Preventative Dental Program Pilot Study

NCT07218068
View directory record Official record
Conditions
Dental Diseases
Interventions
Fluoride varnish, Regular Care, Medical Oncology Care Team
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Bacteria Entering the Blood Stream From Tooth Extractions and Tooth Brushing

NCT00454285
View directory record Official record
Conditions
Bacteremia
Interventions
Effect of Amoxicillin on bacteremia following a single-tooth extraction
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
290 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Sep 4, 2026, 6:24 AM EDT
Recruiting No phase listed Observational

Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)

NCT06669949
View directory record Official record
Conditions
Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)
Interventions
no intervention
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Not applicable Interventional

Wheelchair Maintenance Training Program

NCT03909061
View directory record Official record
Conditions
Remote Maintenance Training Program
Interventions
Wheelchair Maintenance Training
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
Not listed
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Not applicable Interventional Results available

Clinical Performance of Chairside CAD/CAM Restorations

NCT04279574
View directory record Official record
Conditions
Dental Cements, Caries,Dental
Interventions
Lithium disilicate onlays (IPS emaxCAD/Ivoclar), Chairside zirconia crowns (3M)
Device
Lead sponsor
Solventum US LLC
Industry
Eligibility
18 Years to 89 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Glass Ionomer Sealant and Fluoride Varnish Study to Prevent Early Childhood Caries

NCT01129440
View directory record Official record
Conditions
Dental Caries
Interventions
Fluoride Varnish, Glass Ionomer Sealant
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
2 Years to 3 Years
Enrollment
597 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
San Ysidro, California
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental Erosion

NCT01657903
View directory record Official record
Conditions
Dental Erosion, Acid Wear
Interventions
Sodium Fluoride, Potassium nitrate
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 25, 2015 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Not applicable Interventional Results available

A Prospective Study Evaluating the Performance of Nanotite Osseotite Implants When Placed by Graduate Student Programs

NCT00726063
View directory record Official record
Conditions
Tooth Disease, Partial Edentulism
Interventions
Nanotite dental implant, Osseotite dental implant
Device
Lead sponsor
ZimVie
Industry
Eligibility
18 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Evaluate Bone and Gum Dimension Changes Around Dental Implants Placed in Different Positions in Bone.

NCT01759537
View directory record Official record
Conditions
Mouth, Edentulous
Interventions
Ankylos dental endosseous implants-Sub-crestal, Ankylos dental endosseous implants-Epi-crestal
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years to 70 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 28, 2022 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Phase 3 Interventional Results available

Prevention of Adult Caries Study (PACS)

NCT00357877
View directory record Official record
Conditions
Caries, Dental
Interventions
10% w/v chlorhexidine acetate coating FDA IND #45466, Placebo
Drug · Other
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
983 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
4
States / cities
Tuba City, Arizona • Boston, Massachusetts • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain

NCT00631111
View directory record Official record
Conditions
Pain
Interventions
effervescent ibuprofen tablets, effervescent Aspirin plus Vitamin C tablets, ibuprofen tablets, placebo
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
16 Years to 40 Years
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 9, 2009 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Not applicable Interventional Results available

A Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity

NCT01727258
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Mouth Rinse, Fluoride Toothpaste, Potassium Nitrate Toothpaste
Device · Drug
Lead sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 9, 2015 · Synced Sep 4, 2026, 6:24 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

OrthoPulse 2.0 and 2.1 Feasibility Evaluation

NCT03683017
View directory record Official record
Conditions
Malocclusion
Interventions
OrthoPulse 2.0, OrthoPulse 2.1, Invisalign 3.5 Day Wear, Fixed Orthodontic Appliances (Braces)
Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
11 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
6
States / cities
Chandler, Arizona • Peoria, Arizona • Phoenix, Arizona + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2019 · Synced Sep 4, 2026, 6:24 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control

NCT06890676
View directory record Official record
Conditions
Periodontitis, Gingivitis, Periodontal Disease, Periodontal Infections, Oral Infections, Periapical Infections, Pneumonia, Diabetes
Interventions
Comprehensive Oral Evaluation, Intraoral Complete Radiographic Series, • Teledentistry-synchronous and asynchronous, Periodontal Therapy, Periodontal Maintenance Procedure, Application of Caries Arresting Medicament, Oral Hygiene Assistance, Referral for Treatment of Acute Oral Infection
Other · Procedure
Lead sponsor
Missouri Department of Health and Senior Services
Other
Eligibility
60 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Jefferson City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)

NCT02366689
View directory record Official record
Conditions
Dental Plaque, Gingivitis
Interventions
Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride only toothpaste, Cetylpyridinium chloride mouthwash, Fluoride only mouthwash
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Cedar Knolls, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 29, 2016 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Xylitol Disk Use in Adults With Dry Mouth

NCT01823445
View directory record Official record
Conditions
Mutans Streptococci, Xerostomia
Interventions
Xylitol disk
Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 2, 2013 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Phase 2 Interventional Results available

Study of Diclofenac Capsules to Treat Dental Pain

NCT00985439
View directory record Official record
Conditions
Dental Pain
Interventions
Diclofenac Test (lower dose), Diclofenac Test (upper dose), Celecoxib 400 mg, Placebo
Drug
Lead sponsor
Iroko Pharmaceuticals, LLC
Industry
Eligibility
18 Years to 50 Years
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2012 · Synced Sep 4, 2026, 6:24 AM EDT
Recruiting Not applicable Interventional

Effect of Collagen Membrane on Ridge Preservation

NCT07580495
View directory record Official record
Conditions
Dehiscence, Tooth Extraction, Alveolar Bone Loss
Interventions
Minimally Invasive tooth extraction, Alveolar ridge preservation with ABCC, Resorbable collagen membrane (InterCollagen® Guide)
Procedure · Device
Lead sponsor
Debora Dias
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 4, 2026, 6:24 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparing Stainless Steel Crowns With Prefabricated Resin Crowns in Primary Molar Teeth

NCT06713330
View directory record Official record
Conditions
Dental Caries
Interventions
BioFLX crown, 3M Stainless Steel Crown
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
2 Years to 5 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 4, 2026, 6:24 AM EDT
Recruiting Not applicable Interventional

Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease

NCT07478172
View directory record Official record
Conditions
Neuromuscular Diseases (NMD), Amyotrophic Lateral Sclerosis, Myasthenia Gravis, Lambert-eaton Myasthenic Syndrome, Primary Lateral Sclerosis, Spinal Muscular Atrophy, Charcot Marie Tooth Disease (CMT), Fascioscapulohumeral Muscular Dystrophy, Inclusion Body Myositis, Mitochondrial Myopathy, Nemaline Myopathy, Centronuclear Myopathy, Postpolio Syndrome, Pompe Disease (Late-onset), Chronic Inflammatory Demyelinating Polyneuropathy, Hereditary Spastic Paraplegia, Postural Orthostatic Tachycardia Syndrome (POTS), Progressive Muscular Atrophy
Interventions
Whole-body Electrical Muscle Stimulation Exercise
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Sep 4, 2026, 6:24 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

IOA Preventing Occlusal Changes With MAD Use

NCT07103941
View directory record Official record
Conditions
Sleep Related Breathing Disorder, Snoring, Obstructive Sleep Apnea (OSA), Open Bite, Occlusal Changes, Tooth Migration, Posterior Open Bite
Interventions
AM Aligner, Exercise
Device · Behavioral
Lead sponsor
Isabel Moreno Hay
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 4, 2026, 6:24 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Microderm for Root Coverage Procedures

NCT07203326
View directory record Official record
Conditions
Connective Tissue Graft, Gum Recession
Interventions
Alloderm, MicroDerm
Biological
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Sep 4, 2026, 6:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cold Plasma for Dental Restoration and Caries Prevention

NCT01529606
View directory record Official record
Conditions
Dental Restoration, Caries
Interventions
Composite restoration and tooth cleaning, Plasma treatment
Other · Procedure
Lead sponsor
Nanova, Inc
Industry
Eligibility
18 Years to 35 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 15, 2020 · Synced Sep 4, 2026, 6:24 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Happy Teeth for Hopi Tots: Cultural Adaptation of an Oral Health Entertainment-Education Intervention

NCT05297526
View directory record Official record
Conditions
Early Childhood Caries
Interventions
Culturally adapted children's book, Standard informational brochure on children's oral health
Behavioral
Lead sponsor
Northern Arizona University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Flagstaff, Arizona
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Sep 4, 2026, 6:24 AM EDT