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Showing 217–240 of 692 matching trials from the live ClinicalTrials.gov search.
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Investigation of Dental Plaque and Gingival Index

NCT00759031
Conditions
Dental Plaque
Interventions
Sodium Monofluorophosphate, Triclosan/Fluoride/Copolymer
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
New York, New York
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride

NCT01563172
Conditions
Dental Caries
Interventions
Sodium fluoride / silica and carbopol, 0.5g, Sodium fluoride / silica and carbopol, 1.5g, Fluoride free dentifrice
Drug · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 80 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Indianapolis, Indiana
Recruiting No phase listed Observational

Bite Force Measurements

NCT06843525
Conditions
Irreversible Pulpitis, Apical Periodontitis, Pulpal Necrosis
Interventions
Not listed
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 89 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Newark, New Jersey
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Study of Naproxen Capsules to Treat Dental Pain

NCT01229228
Conditions
Dental Pain
Interventions
Naproxen Test, Naprosyn, Placebo
Drug
Lead sponsor
Iroko Pharmaceuticals, LLC
Industry
Eligibility
18 Years to 50 Years
Enrollment
254 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Austin, Texas
Not listed No phase listed Observational Accepts healthy volunteers

Early Caries Lesion Management Observational Study

NCT04933331
Conditions
Initial Caries, Arrested Dental Caries, Cavitated Caries, Dental Caries, Dental Caries in Children
Interventions
Curodont Repair Fluoride Plus, Silver Diamine Fluoride, Glass Ionomer Sealant, Fluoride varnish, Fluoride toothpaste
Drug · Device
Lead sponsor
CareQuest Institute for Oral Health
Other
Eligibility
4 Years and older
Enrollment
744 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
4
States / cities
Dothan, Alabama • Westborough, Massachusetts • Bend, Oregon + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Analysis for Caries Prevention in Children Using a Computer Software

NCT02375763
Conditions
Dental Caries
Interventions
Software instruction
Other
Lead sponsor
Marquette University
Other
Eligibility
3 Years to 13 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Completed Phase 4 Interventional Results available

Benzocaine Gel Toothache Dose-Response Study

NCT00474175
Conditions
Toothache
Interventions
Placebo gel, benzocaine
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
12 Years and older
Enrollment
577 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
8
States / cities
Baltimore, Maryland • Boston, Massachusetts • Detroit, Michigan + 5 more
Completed Not applicable Interventional Accepts healthy volunteers

TEACH: Technology Evaluation to Address Child Health

NCT02912000
Conditions
Smoking, Obesity, Dental Caries
Interventions
TEACH intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Dental Pulp Diseases, Dental Pulp Necrosis, Nerve Root Pain Nec
Interventions
Nanodiamond reinforced Gutta Percha, Gutta Percha
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Charcot Marie Tooth Disease
Interventions
Not listed
Lead sponsor
Michael Shy
Other
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2030
U.S. locations
18
States / cities
Los Angeles, California • Palo Alto, California • Aurora, Colorado + 14 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Use of Clear Aligners With Movement Enhancement Techniques

NCT02087163
Conditions
Malocclusion
Interventions
Movement Enhancement Technique, Clear Aligner
Device
Lead sponsor
Align Technology, Inc.
Industry
Eligibility
16 Years to 46 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Jose, California
Conditions
Charcot Marie Tooth Disease
Interventions
Coenzyme Q10, Coenzyme Q10
Drug · Dietary Supplement
Lead sponsor
Memorial Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Johnstown, Pennsylvania
Completed Not applicable Interventional Results available

Effect of Buffered Numbing Solution on Patients With Toothaches

NCT01868776
Conditions
Irreversible Pulpitis (Toothache)
Interventions
buffered lidocaine, nonbuffered lidocaine
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Dental Plaque, Gingivitis
Interventions
Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride only toothpaste, Cetylpyridinium chloride mouthwash, Fluoride only mouthwash
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Cedar Knolls, New Jersey
Completed Not applicable Interventional Results available

Clinical Performance of Chairside CAD/CAM Restorations

NCT04279574
Conditions
Dental Cements, Caries,Dental
Interventions
Lithium disilicate onlays (IPS emaxCAD/Ivoclar), Chairside zirconia crowns (3M)
Device
Lead sponsor
Solventum US LLC
Industry
Eligibility
18 Years to 89 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Accepts healthy volunteers

RCT Comparing Invisalign and Traditional Orthodontic Treatment

NCT04556448
Conditions
Malocclusion, Angle Class II
Interventions
Aligners, Clear braces
Other
Lead sponsor
Texas A&M University
Other
Eligibility
17 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Tooth Whitening, Tooth Discoloration
Interventions
Vitamin C toothpaste, Matching placebo
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Melbourne, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bone Remodeling After Immediate Implant Placement With and Without Bone Grafting

NCT02174198
Conditions
Tooth Loss
Interventions
BioOss Collagen at the time of implant placement
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
New York, New York
Recruiting Phase 3 Interventional Accepts healthy volunteers

Building Adaptive School-based Interventions for Caries

NCT07265830
Conditions
Dental Caries
Interventions
Silver Diamine Fluoride (38%), Glass Ionomer Sealant, Fluoride Varnishes, Hygiene Intervention
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
5 Years to 13 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Glenwood Springs, Colorado
Completed Not applicable Interventional Accepts healthy volunteers Results available

Analysis of Orthodontic Tooth Movement Using 3D Imaging

NCT03398798
Conditions
Tooth Crowding, Dental Crowding, Malocclusion
Interventions
.014", .016", Twin brackets, Self-ligating brackets
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
10 Years to 45 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Huntersville, North Carolina
Conditions
Dental Disorders Hard Tissues of Teeth, Dental Diseases
Interventions
Crowns self-adhesively luted, Crowns conventionally cemented
Device
Lead sponsor
Ivoclar Vivadent AG
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Accepts healthy volunteers Results available

Older Adult Effectiveness of 2 Treatments

NCT03916926
Conditions
Dental Caries
Interventions
A "simple medical strategy" consisting of silver diamine fluoride (SDF), B "typical dental strategy" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride varnish (FV)
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
62 Years and older
Enrollment
568 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Terminated No phase listed Observational Accepts healthy volunteers

Three-dimensional Assessment of Craniofacial Structures

NCT01210547
Conditions
Malocclusion
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Terminated Early Phase 1 Interventional Accepts healthy volunteers

N-Acetyl Cysteine Protects Pulpal Stem Cells in Endodontic Revascularization

NCT03451435
Conditions
Endodontic Disease
Interventions
N acetyl cysteine
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
6 Years to 18 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Los Angeles, California