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ClinicalTrials.gov public records Last synced Nov 15, 2026, 4:41 AM EST

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Showing 553–576 of 692 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Tooth Diseases Clear all

Conditions: AMPD3, OMIM*102772, AMP Deaminase Deficiency, AK1, OMIM *103000, Adenylate Kinase Deficiency, AMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency, TPMT, OMIM *187680, Thoipurines, Poor Metabolism of, IMPDH1, OMIM *146690, Retinitis Pigmentosa Type 10, Leber Congenital Amauriosis Type 11, APRT, OMIM *102600, Adenine Phosphoribosyltransferase Deficiency, HPRT1, OMIM *308000 Lesch-Nyhan Disease, XDH, OMIM *607633, Xanthinuria Type 1, SLC2A9, OMIM *606142 Hypouricemia, SLC22A12, OMIM *607096 Hypouricemia, PRPS1 Def, OMIM *311850, Arts Syndrome; Charcot-Marie-Tooth Disease, PRPS1 SA, OMIM *311850 Gout, PRPS-related Phosphoribosylpyrophosphate Synthetase Superactivity, AMPD2, OMIM *102771, Spastic Paraplegia 63; Pontocerebellar Hypoplasia, ITPA, OMIM *147520, Inosine Triphosphatase Deficiency; Developmental and Epileptic Encephalopathy 35, ADSL, OMIM *608222, Adenylosuccinate Lyase Deficiency, PNP, OMIM *164050, Nucleoside Phosphorylase Deficiency, ADA2, OMIM *607575,Sneddon Syndrome; VAIHS, CAD, *1140120, Developmental and Epileptic Encephalopathy, UPB1, OMIM *606673, Beta-ureidopropionase Deficiency, DPYS, OMIM *613326, Dihydropyrimidinase Deficiency, DPYD, OMIM *274270, Dihydropyrimidine Dehydrogenase Deficiency, DHODH, OMIM *126064, Miller Syndrome (Postaxial Acrofacial Dysostosis), UMPS, OMIM *613891, Orotic Aciduria, NT5C3A<TAB>, OMIM *606224, Anemia, Hemolytic, Due to UMPH1 Deficiency, UNG, OMIM *191525, Hyper-IgM Syndrome 5, AICDA, OMIM *605257, Immunodeficiency With Hyper-IgM, Type 2; HIGM2, Purine-Pyrimidine Metabolism, Metabolic Disease
Interventions: Not listed
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: 1 Month to 100 Years
Enrollment: 999 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2099
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Dental Plaque, Oral Health, Periodontal Disease and Caries, Periodontal Disease
Interventions: Not listed
Lead sponsor: National Institute of Dental and Craniofacial Research (NIDCR); NIH
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Angina Pectoris, Coronary Artery Disease, Chest Pain, Cardiovascular Diseases, Coronary Heart Disease, CAD, CVD, CHD
Interventions: Corus CAD (ASGES); Diagnostic Test
Lead sponsor: CardioDx; Industry
Eligibility: 21 Years to 99 Years
Enrollment: 171 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Dental Caries
Interventions: Resin infiltration, Caries management; Device · Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 14 Years to 35 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Toledo, Ohio

Conditions: Caries, Salivary Function, Tooth Sensitivity
Interventions: Resin infiltration, Mock treatment; Device · Other
Lead sponsor: DMG Dental Material Gesellschaft mbH; Industry
Eligibility: 19 Years and older
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Preventive Oral Health
Interventions: Hands on training, Web based training; Other
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: 22 Years to 50 Years
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Tooth Erosion
Interventions: Sodium fluoride, Sodium monoflurophosphate, Sterile water; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Malocclusion
Interventions: Motion View, Conventional Orthodontic Treatment; Procedure
Lead sponsor: Harvard School of Dental Medicine; Other
Eligibility: Up to 60 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tooth Movement, Malocclusion
Interventions: AcceleDent, Vibrational Device; Device
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Jaw, Edentulous, Partially
Interventions: Astra Tech Fixture ST; Device
Lead sponsor: Dentsply Sirona Implants and Consumables; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2000
U.S. locations: 2
States / cities: New York, New York

Conditions: Tooth Erosion
Interventions: Experimental Dentifrice, Placebo Control Dentifrice, Reference Dentifrice; Drug
Lead sponsor: HALEON; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Dentin Hypersensitivity
Interventions: Stannous fluoride and Potassium nitrate Dentifrice, Stannous fluoride Dentifrice, Potassium nitrate Dentifrice, Vehicle Dentifrice; Drug
Lead sponsor: HALEON; Industry
Eligibility: 12 Years to 65 Years
Enrollment: 688 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 3
States / cities: Melbourne, Florida • Fort Wayne, Indiana • Las Vegas, Nevada

Conditions: Malocclusion
Interventions: Movement Enhancement Technique, Clear Aligner; Device
Lead sponsor: Align Technology, Inc.; Industry
Eligibility: 16 Years to 46 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: San Jose, California

Conditions: Dentin Sensitivity
Interventions: Control toothpaste containing Novamin® technology, Control toothpaste containing 1500 ppm fluoride as MFP, Test toothpaste with nano-HAP (high concentration), Test toothpaste with nano-HAP (low concentration), Test toothpaste with nano-HAP and (Potassium Nitrate) KNO3, Control toothpaste without nano-HAP, Test toothpaste with nano-HAP (medium concentration), Test cream with nano-HAP (higher concentration), Control cream without nano-HAP; Drug
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 80 Years
Enrollment: 203 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Periodontitis, Dental Plaque
Interventions: ADA approved Manual Toothbrush, Marketed Power Toothbrush; Device
Lead sponsor: Philips Clinical & Medical Affairs Global; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 346 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Apical Periodontitis, Endodontically Treated Teeth, Endodontic Disease, Apical Cyst, Apical Granuloma, Periradicular Disease, Previous Endodontic Treatment
Interventions: PBM treatment, PBM sham treatment, EMS; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Overweight
Interventions: CHICA GIS (enhanced electronic medical record); Other
Lead sponsor: Indiana University; Other
Eligibility: 1 Year to 21 Years
Enrollment: 1,076 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Dental Pulp Disease
Interventions: Not listed
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 16 Years to 80 Years
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2015
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Gingivitis, Plaque, Calculus, Dental
Interventions: RF-utilizing powered toothbrush, Control placebo with no RF; Device
Lead sponsor: Home Skinovations Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Dental Caries
Interventions: Educational Intervention, Referral Intervention; Behavioral
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: Not listed
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Dental Caries, Oral Cavity Cancer, Oral Complications of Chemotherapy and Head/Neck Radiation
Interventions: Tray, Brush; Other
Lead sponsor: A.T. Still University of Health Sciences; Other
Eligibility: 18 Years to 100 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Mesa, Arizona

Conditions: Tooth Loss
Interventions: BioOss Collagen at the time of implant placement; Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Dental Pain
Interventions: Maxigesic 325, Acetaminophen, Ibuprofen, Placebo; Drug
Lead sponsor: AFT Pharmaceuticals, Ltd.; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 408 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Jaw, Edentulous, Partially
Interventions: ASTRA TECH Implant System, OsseoSpeed™; Device
Lead sponsor: Dentsply Sirona Implants and Consumables; Industry
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2012
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Search by objective public record fields.

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Bacterial Arrangement on the Teeth

Utility of a Molecular Personalized Coronary Gene Expression Test (Corus CAD or ASGES) on Cardiology Practice Pattern

Radiographic Progression of Infiltrated Caries Lesions In-vivo

Lesion Progression After Icon Treatment in Young Adults

Oral Health Training Program for Pediatric Residents

Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion

A Comparison of the Alignment Achieved Using Computer-guided Indirect Bonding of Orthodontic Brackets to Conventional Appliance Placement

Accelerated Tooth Movement With AcceleDent® and Aligners - a Pilot Project

Study to Evaluate Implant Survival Rate of Astra Tech Fixture ST in the Posterior Maxilla With One-stage Surgery and Early Loading

An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel

Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice

The Use of Clear Aligners With Movement Enhancement Techniques

Clinical Efficacy in Relieving Dentin Hypersensitivity of Nanohydroxyapatite-Containing Toothpastes and Cream

At-Home Care for Subjects With Periodontitis

Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery

Delivering Geospatial Intelligence to Health Care Providers

Sodium Channel Expression in Human Teeth

ToothWave Calculus Reduction and Accumulation Prevention Study

Waukesha Smiles: Dental Outreach to Low-income Waukesha Children

Impact of Compliance With Fluoride Use on Caries Incidence After Cancer Therapy

Bone Remodeling After Immediate Implant Placement With and Without Bone Grafting

Maxigesic 325 Acute Dental Pain Study

Study to Compare Survival for ASTRA TECH Implant System, OsseoSpeed™ Implants Following Immediate Loading in Extraction Sockets Versus Immediate Loading in Healed Ridges